Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development

The Role of Polyamines in Supporting Growth of Mammalian Cells Is Mediated through Their Requirement for Translation Initiation and Elongation

(2010) Guy Landau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice

(2010) Bernhard Maier et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence for conformational changes in the yeast deoxyhypusine hydroxylase Lia1 upon iron displacement from its active site

(2009) Veridiana S. P. Cano et al.   AMINO ACIDS

Functional significance of eIF5A and its hypusine modification in eukaryotes

(2009) M. H. Park et al.   AMINO ACIDS

eIF5A has a function in the elongation step of translation in yeast

(2009) Ana P.B. Gregio et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TheDrosophiladeoxyhypusine hydroxylase homologueneroand its target eIF5A are required for cell growth and the regulation of autophagy

(2009) Prajal H. Patel et al.   JOURNAL OF CELL BIOLOGY

Hypusine-containing protein eIF5A promotes translation elongation

(2009) Preeti Saini et al.   NATURE

Crystal structure of human eIF5A1: Insight into functional similarity of human eIF5A1 and eIF5A2

(2009) Yufeng Tong et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A

(2009) Mainul Hoque et al.   Retrovirology

Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine

(2008) M. K. Chattopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma

(2007) Dan Xie et al.   HUMAN PATHOLOGY