Protein scaffold-based molecular probes for cancer molecular imaging

Generation of tumour-necrosis-factor-α-specific affibody molecules capable of blocking receptor bindingin vitro

(2009) Andreas Jonsson et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects

(2009) R. H. Kimura et al.   CANCER RESEARCH

Biosynthesis and Biological Screening of a Genetically Encoded Library Based on the Cyclotide MCoTI-I

(2009) Jeffrey Austin et al.   CHEMBIOCHEM

Engineered Two-Helix Small Proteins for Molecular Recognition

(2009) Jack M. Webster et al.   CHEMBIOCHEM

Potent Inhibitors of β-Tryptase and Human Leukocyte Elastase Based on the MCoTI-II Scaffold

(2009) Panumart Thongyoo et al.   JOURNAL OF MEDICINAL CHEMISTRY

A 2-Helix Small Protein Labeled with 68Ga for PET Imaging of HER2 Expression

(2009) G. Ren et al.   JOURNAL OF NUCLEAR MEDICINE

Affibody Molecules for Epidermal Growth Factor Receptor Targeting In Vivo: Aspects of Dimerization and Labeling Chemistry

(2009) V. Tolmachev et al.   JOURNAL OF NUCLEAR MEDICINE

Changes in HER2 Expression in Breast Cancer Xenografts After Therapy Can Be Quantified Using PET and 18F-Labeled Affibody Molecules

(2009) G. Kramer-Marek et al.   JOURNAL OF NUCLEAR MEDICINE

Targeting of HER2-Expressing Tumors with a Site-Specifically 99mTc-Labeled Recombinant Affibody Molecule, ZHER2:2395, with C-Terminally Engineered Cysteine

(2009) S. Ahlgren et al.   JOURNAL OF NUCLEAR MEDICINE

On the Selection of a Tracer for PET Imaging of HER2-Expressing Tumors: Direct Comparison of a 124I-Labeled Affibody Molecule and Trastuzumab in a Murine Xenograft Model

(2009) A. Orlova et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of a Maleimido Derivative of CHX-A′′ DTPA for Site-Specific Labeling of Affibody Molecules

(2008) Vladimir Tolmachev et al.   BIOCONJUGATE CHEMISTRY

Affibody Molecules for In vivo Characterization of HER2-Positive Tumors by Near-Infrared Imaging

(2008) S. B. Lee et al.   CLINICAL CANCER RESEARCH

Development and preclinical characterisation of 99mTc-labelled Affibody molecules with reduced renal uptake

(2008) Torun Ekblad et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Construction of a Large Phage-Displayed Human Antibody Domain Library with a Scaffold Based On a Newly Identified Highly Soluble, Stable Heavy Chain Variable Domain

(2008) Weizao Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Small-Animal PET Imaging of Human Epidermal Growth Factor Receptor Type 2 Expression with Site-Specific 18F-Labeled Protein Scaffold Molecules

(2008) Z. Cheng et al.   JOURNAL OF NUCLEAR MEDICINE

Comparison of the Biodistribution and Tumor Targeting of Two 99mTc-Labeled Anti-EGFR Nanobodies in Mice, Using Pinhole SPECT/Micro-CT

(2008) L. O. T. Gainkam et al.   JOURNAL OF NUCLEAR MEDICINE

SPECT Imaging with 99mTc-Labeled EGFR-Specific Nanobody for In Vivo Monitoring of EGFR Expression

(2008) Lieven Huang et al.   MOLECULAR IMAGING AND BIOLOGY

Engineering of a femtomolar affinity binding protein to human serum albumin

(2008) A. Jonsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Evaluation of Maleimide Derivative of DOTA for Site-Specific Labeling of Recombinant Affibody Molecules

(2007) Sara Ahlgren et al.   BIOCONJUGATE CHEMISTRY