4.4 Article

PROlocalizer: integrated web service for protein subcellular localization prediction

Journal

AMINO ACIDS
Volume 40, Issue 3, Pages 975-980

Publisher

SPRINGER WIEN
DOI: 10.1007/s00726-010-0724-y

Keywords

Protein localization prediction; Cell compartments; Mutations; Disease-causing mutations; Prediction method

Funding

  1. Biocenter Finland
  2. Finnish Academy [213462]
  3. Tampere University Hospital
  4. Sigrid Juselius Foundation
  5. Tampere Graduate School in Information Science and Engineering (TISE)
  6. Otto A. Malm Foundation

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Subcellular localization is an important protein property, which is related to function, interactions and other features. As experimental determination of the localization can be tedious, especially for large numbers of proteins, a number of prediction tools have been developed. We developed the PROlocalizer service that integrates 11 individual methods to predict altogether 12 localizations for animal proteins. The method allows the submission of a number of proteins and mutations and generates a detailed informative document of the prediction and obtained results. PROlocalizer is available at http://bioinf.uta.fi/PROlocalizer/.

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