Editorial Material
Medicine, General & Internal
Mario Puerta-Pena, Alba Calleja Algarra
Summary: This is a case report of a 64-year-old male who developed mild diarrhea and an itchy, migratory, serpiginous rash after receiving glucocorticoid therapy.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Respiratory System
Jonathan M. Czeresnia, Louis M. Weiss
Summary: Strongyloidiasis is a parasitic disease caused by Strongyloides stercoralis, affecting over 600 million people worldwide. It can be transmitted through skin penetration or ingestion. Self-infection can lead to chronic asymptomatic infection, while hyperinfection can cause life-threatening diseases. Diagnosis can be done through direct visualization or serology, and treatment with ivermectin is highly effective.
Article
Parasitology
Ghazanfar Abbas, Abdul Ghafar, Anson Koehler, Jenni Bauquier, Edwina J. A. Wilkes, Caroline Jacobson, Anne Beasley, John Hurley, Lucy Cudmore, Peter Carrigan, Brett Tennent-Brown, Charles El-Hage, Martin K. Nielsen, Charles G. Gauci, Kristopher J. Hughes, Ian Beveridge, Abdul Jabbar
Summary: This study successfully detected Strongyloides sp. DNA in the feces of foals using molecular phylogenetic methods, providing a new way for future molecular epidemiological studies on Strongyloides westeri in horses.
PARASITES & VECTORS
(2021)
Letter
Immunology
Jani M. Kim, Geetha Sivasubramanian
Summary: The widespread use of corticosteroids for COVID-19 treatment has resulted in the reactivation of Strongyloides and the occurrence of severe disease in patients from endemic areas. We report a case of a US patient with COVID-19 and Strongyloides hyperinfection syndrome, and review other reported cases. Our findings emphasize the importance of Strongyloides screening and treatment in high-risk populations.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Margaret M. Chapman, Victorine V. Muse, James E. Mojica, Melis N. Anahtar
Summary: A 50-year-old woman with sarcoidosis presented with pain in the left upper quadrant and hypoxemia. Chest radiography revealed consolidations in the middle and lower lobes with diffuse ground-glass opacities. A diagnostic test was performed to further evaluate the condition.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Parasitology
Maria Sophia Unterkoefler, Iris Eipeldauer, Sophie Merz, Nikola Pantchev, Josef Hermann, Rene Brunthaler, Walter Basso, Barbara Hinney
Summary: This article presents two cases of severe canine Strongyloides stercoralis infection in Austria. The authors emphasize that the infection may be overlooked in Austria and the Baermann funnel technique is necessary for diagnosis. In addition, treatment with moxidectin may not always eliminate the infection, and ivermectin should be considered.
PARASITES & VECTORS
(2022)
Article
Computer Science, Artificial Intelligence
Xiang Bai, Hanchen Wang, Liya Ma, Yongchao Xu, Jiefeng Gan, Ziwei Fan, Fan Yang, Ke Ma, Jiehua Yang, Song Bai, Chang Shu, Xinyu Zou, Renhao Huang, Changzheng Zhang, Xiaowu Liu, Dandan Tu, Chuou Xu, Wenqing Zhang, Xi Wang, Anguo Chen, Yu Zeng, Dehua Yang, Ming-Wei Wang, Nagaraj Holalkere, Neil J. Halin, Ihab R. Kamel, Jia Wu, Xuehua Peng, Xiang Wang, Jianbo Shao, Pattanasak Mongkolwat, Jianjun Zhang, Weiyang Liu, Michael Roberts, Zhongzhao Teng, Lucian Beer, Lorena E. Sanchez, Evis Sala, Daniel L. Rubin, Adrian Weller, Joan Lasenby, Chuangsheng Zheng, Jianming Wang, Zhen Li, Carola Schonlieb, Tian Xia
Summary: Artificial intelligence shows promise in streamlining COVID-19 diagnoses, but concerns around security and trustworthiness hinder the collection of large-scale medical data. The Unified CT-COVID AI Diagnostic Initiative (UCADI) introduces a federated learning framework for training AI models without data sharing, achieving comparable performance with professional radiologists. This study, based on data from 23 hospitals in China and the UK, advances the use of federated learning for privacy-preserving AI in digital health.
NATURE MACHINE INTELLIGENCE
(2021)
Article
Genetics & Heredity
Astra S. Bryant, Stephanie F. DeMarco, Elissa A. Hallem
Summary: Approximately 1 billion people worldwide are infected with soil-transmitted gastrointestinal parasitic nematodes, with skin-penetrating Strongyloides nematodes emerging as model organisms for research. To facilitate genomics studies of Strongyloides species, a web-based application called the Strongyloides RNA-seq Browser has been developed to provide an open source portal for accessing and analyzing genomic expression data.
G3-GENES GENOMES GENETICS
(2021)
Article
Health Care Sciences & Services
Scott Claxton, Paul Porter, Joanna Brisbane, Natasha Bear, Javan Wood, Vesa Peltonen, Phillip Della, Claire Smith, Udantha Abeyratne
Summary: The study developed a smartphone-based algorithm for rapid and accurate diagnosis of AECOPD, utilizing patient-reported features and cough sound data. The algorithm showed high diagnostic accuracy in primary care settings, aiding in early identification of AECOPD.
NPJ DIGITAL MEDICINE
(2021)
Article
Critical Care Medicine
Sujith Cherian, Dhara Patel, Stephen Machnicki, David Naidich, Diane Stover, William D. Travis, Kevin K. Brown, Jason J. Naidich, Akhilesh Mahajan, Michael Esposito, Bushra Mina, Viera Lakticova, Stuart L. Cohen, Nestor L. Muller, Jenna Schulner, Rakesh Shah, Suhail Raoof
Summary: Organizing pneumonia is a lung disease characterized by the filling of alveoli and bronchioles with loose connective tissue. It can be caused by various factors, and its clinical and radiographic presentations are diverse. Histopathologic confirmation and exclusion of other causes may be necessary for diagnosis. Treatment usually involves long-term steroid use, but relapses are common.
Article
Oncology
Jesus Fuentes-Antras, Aranzazu Manzano, Gloria Marquina, Mateo Paz, Carlos Aguado, Monica Granja, Javier Benitez, Justo Ortega, Araceli Priego, Carlos Gonzalez, Julia Tejerina-Peces, Paloma Flores, Alfonso Lopez de Sa, Carmen Toledano, Jennifer Olalla, Alicia de Luna, Jorge Bartolome, Pedro Perez-Segura
Summary: The COVID-19 pandemic has a significant impact on cancer patients, especially when symptoms such as dyspnea and low oxygen saturation levels present. Study findings show that patients with features on admission such as dyspnea, higher qSOFA score, higher C-reactive protein levels, and abnormal neutrophil count are at higher risk of in-hospital death.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Biochemistry & Molecular Biology
Stefania Pane, Anna Sacco, Andrea Iorio, Lorenza Romani, Lorenza Putignani
Summary: This study investigated the gut microbiota of a pediatric case of strongyloidiasis, revealing an increase in microbial diversity during infection and one month post-infection, followed by a decrease two months post-infection. Functional prediction highlighted an enrichment of microbial glycan and carbohydrate metabolisms in the infected sample compared to healthy controls.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Branson Taheri, Huai-Ching Kuo, Nicole Hockenbury, Dan Lu, Edward Mitre, Patrick W. Hickey
Summary: This study examines the impact of occupational risk and immigration status on Strongyloides stercoralis infections in the Military Health System (MHS) over an 8-year period. The results indicate that military service members, particularly those in healthcare occupations, as well as immigrant patients and individuals aged 65 and older, are at increased risk of infection.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Jeremy Grossman, Jun Fan, Felicia Allard, Jane Moon, Luis A. Marcos
Summary: This article reports a fatal case of S. stercoralis hyperinfection in an immigrant from rural Ecuador and emphasizes the importance of screening for this parasite in the appropriate clinical scenarios. Various diagnostic methods are introduced to make the diagnosis of S. stercoralis more accessible to practitioners.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Immunology
Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Haruko Saito, Yuko Abe, Eri Akiba, Kako Haduki, Tadayoshi Nitta, Akira Kawano, Michio Tanaka, Yumi Hattori, Takahiro Kawasaki, Takanori Matsuki, Takayuki Shiroyama, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Masahide Mori, Seigo Kitada, Shota Nakamura, Tetsuya Iida, Atsushi Kumanogoh, Hiroshi Kida
Summary: We identified a novel Tsukamurella species, Tsukamurella toyonakaense, which was misdiagnosed as nontuberculous mycobacterial pulmonary disease caused by unidentified mycobacteria. Genomic identification of this Tsukamurella species helped clarify its clinical characteristics and epidemiology.
EMERGING INFECTIOUS DISEASES
(2022)
