Article
Immunology
Robert E. Snyder, Gail Sondermeyer Cooksey, Vicki Kramer, Seema Jain, Duc J. Vugia
Summary: WNV-associated hospitalizations in California were substantial and costly, with higher incidence in males, elderly persons, and patients with underlying conditions. WNV remains a costly and severe public health threat in California.
CLINICAL INFECTIOUS DISEASES
(2021)
Letter
Immunology
Gino Arcilla, Antoine Nguyen, Antonio Liu
Summary: We encountered a patient with HIV who showed rapid deterioration in mental status and was positive for both acute West Nile encephalitis and amphiphysin antibodies. After reviewing the literature, we found Dr. Moutsopoulos's paper from your journal highly interesting (Karagianni et al., 2019 [1]). Although autoimmune encephalitis following West Nile encephalitis is not uncommon, there are several intriguing aspects in our patient's case. Firstly, the coexistence of amphiphysin antibodies with West Nile encephalitis has not been reported before. Secondly, the monophasic clinical course suggests that autoimmune encephalitis triggered by or coexisting with West Nile encephalitis may be significantly underrecognized. Lastly, our patient was HIV positive but not severely immunocompromised, which may have contributed to the autoimmune status.
CLINICAL IMMUNOLOGY
(2023)
Letter
Medicine, General & Internal
Claire Waller, Marianne Tiemensma, Bart J. Currie
Summary: A patient diagnosed with Japanese encephalitis in February 2021 has been identified as a likely sentinel human case of the 2022 outbreak of the disease in Australia.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Letter
Medicine, General & Internal
Claire Waller, Marianne Tiemensma, Bart J. Currie
Summary: A patient diagnosed with Japanese encephalitis in February 2021 is identified as a likely sentinel human case of the 2022 outbreak of the disease in Australia, raising alerts.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Multidisciplinary Sciences
Sebastien Lamontagne, Axel Suckow, Christoph Gerber, Alec Deslandes, Cornelia Wilske, Steven Tickell
Summary: The study evaluated the source of groundwater in the Mataranka Springs Complex in northern Australia, finding that it is mainly influenced by groundwater from the Daly and Georgina basins, with implications for unconventional gas development in the Beetaloo Sub-basin.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Raymond A. Soto, Emily McDonald, Pallavi Annambhotla, Jason O. Velez, Janeen Laven, Amanda J. Panella, Kimberly D. Machesky, Jennifer L. White, Judie Hyun, Emily Freuck, Janice Habel, David Oh, Marilyn Levi, Rick Hasz, Elling Eidbo, J. Erin Staples, Sridhar Basavaraju, Carolyn Gould
Summary: West Nile virus, the most common domestic arbovirus in the United States, can be transmitted through solid organ transplantation and cause neuroinvasive disease. Organ procurement organizations should consider screening during region-specific WNV transmission months due to increased illness and death in transplant recipients.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Julia Schneider, Friederike Bachmann, Mira Choi, Lille Kurvits, Marie Luisa Schmidt, Leon Bergfeld, Iris Meier, Marta Zuchowski, Dirk Werber, Joerg Hofmann, Klemens Ruprecht, Kai-Uwe Eckardt, Terry C. Jones, Christian Drosten, Victor Max Corman
Summary: The West Nile Virus (WNV) infections are increasingly detected in central Europe, with the first mosquito-borne autochthonous human infection detected in Germany in 2019. This case study described a WNV-encephalitis case in a 33-year-old kidney transplant recipient, which highlighted the importance of considering WNV in cases of meningoencephalitis, especially in immunocompromised patients. Proper education, communication, and revised diagnostic strategies are essential in raising awareness and detecting future WNV infections.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Immunology
Yoshua Colyn Collins-Sawaragi, Patra Koletsi, Eleanor Elizabeth Donlevy, Simon Bruce Drysdale
Summary: This article presents a case of initial seronegative West Nile virus encephalitis in an immunocompromised child and highlights that diagnostic guidelines may not be applicable to immunocompromised patients.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Multidisciplinary Sciences
Yanping Zhang, Wenwen Lei, Yali Wang, Haitian Sui, Bo Liu, Fan Li, Ying He, Zhaoxia Li, Shihong Fu, Lu Wang, Limin Xu, Muti Mahe, Zhenguo Gao, Tuerxun Mamutijiang, Zhi Lv, Nijuan Xiang, Lei Zhou, Daxin Ni, Guodong Liang, Qun Li, Huanyu Wang, Zijian Feng
Summary: The research investigated WNV infection in Kashgar Region, Xinjiang from 2013 to 2016, revealing that WNV mainly occurs between August and September each year, with a higher proportion of male patients. The study also found that Culex pipiens is the dominant mosquito species responsible for transmission, emphasizing the importance of continued surveillance of mosquitoes and avian species.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Pham-Tue-Hung Tran, Urban Hoglund, Olivia Larsson, Sofia Appelberg, Ali Mirazimi, Magnus Johansson, Wessam Melik
Summary: In this study, the use of RVPs based on the Kunjin strain of WNV (WNVKUN) as a potential WNV vaccine candidate was characterized. It was found that the inclusion of CCHFV Gn and Gc proteins in WNVKUN RVPs enhanced the immunogenicity, providing a possibility for the development of a future WNV vaccine.
Article
Multidisciplinary Sciences
Shih-Ching Lin, Fang R. Zhao, Hana Janova, Adrian Gervais, Summer Rucknagel, Kristy O. Murray, Jean-Laurent Casanova, Michael S. Diamond
Summary: This study investigates the ability of West Nile virus (WNV) to directly infect gastrointestinal (GI) tract cells and contribute to disease severity. The results show that GI tract cells become infected when STAT1 or type I interferon responses are absent, leading to increased gut and blood-brain barrier permeability, accumulation of gut-derived molecules in the brain, and more severe WNV disease.
NATURE COMMUNICATIONS
(2023)
Article
Virology
Shannon E. Ronca, Sarah M. Gunter, Rebecca Berry Kairis, Allison Lino, Jonathan Romero, Robia G. Pautler, Alan Nimmo, Kristy O. Murray
Summary: This study found a correlation between substance P and its receptor Neurokinin-1 in West Nile neuroinvasive disease. Blocking this interaction from disease onset modestly improved survival and prolonged time to death. The study has important implications for the development of new therapeutic options.
Article
Multidisciplinary Sciences
Anna Nagy, Nikolett Csonka, Maria Takacs, Eszter Mezei, Eva Barabas
Summary: A comprehensive serosurvey conducted in Hungary in 2019 revealed a seroprevalence of 4.32% for West Nile virus (WNV) and confirmed five cases of Usutu virus (USUV) infection among blood donors. The study also found a spatial pattern of seroprevalence, with Central, Eastern, and Southern Hungary having the highest rates. These findings highlight the importance of increased surveillance and awareness for high-risk areas.
Article
Virology
Guohua Li, Xianyong Meng, Zhiguang Ren, Entao Li, Feihu Yan, Jing Liu, Ying Zhang, Zhanding Cui, Yuetao Li, Hongli Jin, Zengguo Cao, Le Yi, Pei Huang, Hang Chi, Hualei Wang, Weiyang Sun, Tiecheng Wang, Yuwei Gao, Yongkun Zhao, Songtao Yang, Xianzhu Xia
Summary: West Nile virus disease is caused by the arthropod-borne West Nile virus, posing a significant public health risk. The constructed ChiVax-WN01 chimera exhibits distinct characteristics compared to other strains, with moderate safety and immunogenicity demonstrated in animal studies.
Article
Public, Environmental & Occupational Health
Eron G. Manusov, Amalia Mora Campuzano, Omar Ahmed, Samantha Macias, Carolina Gomez de Ziegler, Gerardo Munoz Monaco
Summary: West Nile virus infections have surged in South Texas, with varying clinical manifestations leading to diagnostic challenges. Additionally, pandemics like SARS-CoV-2 can overwhelm the healthcare system and result in medical decision bias errors.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Nivanka De Silva, Justin Jackson, Christopher Steer
INTERNAL MEDICINE JOURNAL
(2018)
Review
Infectious Diseases
Justin Jackson, Caroline Chen, Kirsty Buising
CURRENT OPINION IN INFECTIOUS DISEASES
(2013)
Article
Cardiac & Cardiovascular Systems
Luke Bonavia, Justin Jackson, Jennifer Pui-Yee Law, Michael Yii, Dhaval Joshi
CARDIOVASCULAR PATHOLOGY
(2019)
Editorial Material
Clinical Neurology
Luke Bonavia, Justin Jackson
JOURNAL OF NEURO-OPHTHALMOLOGY
(2022)
Editorial Material
Clinical Neurology
Luke Bonavia, Benjamin McOwan, Justin Jackson
JOURNAL OF CLINICAL NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
Samuel Thorburn, Deborah Friedman, John Burston, Paul M. Kinsella, Genevieve E. Martin, Deborah A. Williamson, Justin Jackson
Summary: Prior to January 2022, there was only one reported case of Japanese encephalitis virus (JEV) infection on the Australian mainland, acquired in the northern extremity on Cape York. We present the clinical characteristics of a cluster of cases confirming the local acquisition of JEV in southern Australia along the Murray River bordering New South Wales and Victoria.
INTERNAL MEDICINE JOURNAL
(2023)
Article
Multidisciplinary Sciences
Nompilo J. Moyo, Ee Laine C. Tay, James P. Trauer, Leona T. Burke, Justin F. Jackson, Robert F. Commons, Sarah F. Boyd, Kasha F. Singh, Justin F. Denholm
Summary: Background regionality plays a significant role in tuberculosis management and outcomes. This study compared TB treatment in regional and metropolitan areas, and observed that regional areas had a slightly longer treatment delay but similar outcomes compared to metropolitan areas.
Article
Medicine, General & Internal
Luke John Bonavia, Justin Jackson, Richard Jurevics
Article
Immunology
Justin Jackson, Alistair McGregor, Louise Cooley, Jimmy Ng, Mitchell Brown, Chong Wei Ong, Catharine Darcy, Vitali Sintchenko
EMERGING INFECTIOUS DISEASES
(2012)