Article
Clinical Neurology
P. H. Espino, R. G. Couper, J. G. Burneo
Summary: Neurocysticercosis (NCC) is a global public health problem and a preventable cause of epilepsy in developing countries. Epileptic seizures are the most common manifestation of NCC and can occur at any stage of the disease. The exact mechanisms underlying NCC-related epilepsy are still poorly understood, with potential explanations including direct causality, initial injury, external factors, and coincidence.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2022)
Review
Infectious Diseases
Roberto Pineda-Reyes, A. Clinton White
Summary: This review provides updated information on the diagnosis, management, and prevention of neurocysticercosis (NCC). Advances in the treatment of subarachnoid NCC, including prolonged antiparasitic and anti-inflammatory courses, as well as new diagnostic and follow-up methods are discussed. Calcified neurocysticercosis remains a burden. Field studies demonstrate the feasibility of elimination using a combination of different treatment methods.
CURRENT OPINION IN INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Nnennaya U. Opara
Summary: Neurocysticercosis is a common cause of recent-onset seizures in tropical areas, and can also lead to bilateral cortical blindness. It remains unclear whether healthy adolescents without pre-existing health problems are vulnerable to such sequelae. We report a case of a 14-year-old Nigerian boy with bilateral cortical blindness caused by neurocysticercosis, despite appropriate treatment most symptoms resolved, but the patient remained permanently blind.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2022)
Review
Clinical Neurology
Teresa Julieta Simoes Steyn, Amalia Naita Awala, Anja de Lange, Joseph Valentino Raimondo
Summary: Neurocysticercosis (NCC) is the most prevalent parasitic infection of the central nervous system caused by Taenia solium larvae. Seizures are the most common symptom of NCC and it is considered the leading cause of preventable epilepsy worldwide. However, a thorough understanding of seizure generation in NCC is still lacking.
Article
Clinical Neurology
Charles E. Makasi, Andrew M. Kilale, Bernard J. Ngowi, Yakobo Lema, Victor Katiti, Michael J. Mahande, Elizabeth F. Msoka, Dominik Stelzle, Andrea S. Winkler, Blandina T. Mmbaga
Summary: This study aimed to explore the knowledge, perceptions, and experiences of epilepsy among people with epilepsy (PWE) and their caregivers attending mental health clinics. The results showed that there were misconceptions about epilepsy, with participants commonly defining it as a falling disease caused by witchcraft, and they were unaware of the association between neurocysticercosis (NCC) and epilepsy. Stigmatization of epilepsy was reported as a problem, highlighting the need for improved health education.
Article
Medicine, General & Internal
Sheyla Gonzalez, Richard Medina-Perez, Danay Herrera, Jose Mario Acosta Rullan, Jose L. Lopez
Summary: Neurocysticercosis (NCC) is the most common parasitic infection of the CNS in humans, caused by the cystic larvae Taenia solium. Clinical presentation varies, and radiological imaging plays a crucial role in determining the disease stage.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
John F. Vargas Urbina, Raul E. Martinez Silva, Fernando Palacios Santos
Summary: Neurocysticercosis is a neurological disease, with the subarachnoid subtype being a severe form that can cause strokes. Diagnosis is primarily done through serology and imaging, with treatment mainly consisting of medication. This case report highlights the experience of a 28-year-old male who suffered from multiple strokes and showed improvement with medical treatment.
REVISTA DEL CUERPO MEDICO DEL HOSPITAL NACIONAL ALMANZOR AGUINAGA ASENJO
(2023)
Article
Medicine, General & Internal
Elumalai Arthi, R. Selvi
Summary: Neurocysticercosis (NCC) is a leading cause of epilepsy in developing countries and is a major neglected disease according to WHO. A study conducted in Southern India found that around 20% of epilepsy patients may have NCC, suggesting a prevalent exposure in the population and the need for its consideration in treatment of epilepsy cases. The study revealed the most common disease stage and the detection rates of anti-cysticercal antibodies, providing insights into the epidemiology of NCC in the region.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
(2021)
Article
Immunology
Carrie E. Lasky, Kara E. Jamison, Darcie R. Sidelinger, Carmela L. Pratt, Guoquan Zhang, Charles R. Brown
INFECTION AND IMMUNITY
(2015)
Article
Immunology
Carrie E. Lasky, Rachel M. Olson, Charles R. Brown
INFECTION AND IMMUNITY
(2015)
Article
Immunology
Carolyn A. Lacey, Lauren L. Keleher, William J. Mitchell, Charles R. Brown, Jerod A. Skyberg
JOURNAL OF INFECTIOUS DISEASES
(2016)
Article
Immunology
Carrie E. Lasky, Carmela L. Pratt, Kinsey A. Hilliard, John L. Jones, Charles R. Brown
FRONTIERS IN IMMUNOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Yan Zhang, Rachel M. Olson, Charles R. Brown
JOURNAL OF LIPID RESEARCH
(2017)
Article
Immunology
Kinsey A. Hilliard, Charles R. Brown
JOURNAL OF IMMUNOLOGY
(2019)
Article
Pharmacology & Pharmacy
Khanh-Van Ho, Kathy L. Schreiber, Danh C. Vu, Susan M. Rottinghaus, Daniel E. Jackson, Charles R. Brown, Zhentian Lei, Lloyd W. Sumner, Mark V. Coggeshall, Chung-Ho Lin
FRONTIERS IN PHARMACOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Kinsey A. Hilliard, Victoria A. Blaho, Christa D. Jackson, Charles R. Brown
Article
Pharmacology & Pharmacy
Khanh-Van Ho, Kathy L. Schreiber, Jihyun Park, Phuc H. Vo, Zhentian Lei, Lloyd W. Sumner, Charles R. Brown, Chung-Ho Lin
FRONTIERS IN PHARMACOLOGY
(2020)
Article
Agronomy
Khanh-Van Ho, Novianus Efrat, Kathy L. Schreiber, Phuc H. Vo, Marco N. De Canha, Analike Blom van Staden, Bianca D. Payne, Carel B. Oosthuizen, Danielle Twilley, Zhentian Lei, Lloyd W. Sumner, Charles R. Brown, Namrita Lall, Chung-Ho Lin
Summary: This study evaluated the anti-inflammatory properties of switchgrass and identified compounds in switchgrass extracts that inhibit the expression of inflammatory mediators. Different cultivars of switchgrass showed varying degrees of inhibition on the secretion of inflammatory mediators. Metabolomics and chromatography-mass spectrometry analyses were used to identify bioactive anti-inflammatory compounds in switchgrass. The Alamo and Kanlow cultivars of switchgrass showed potential as a natural source of anti-inflammatory compounds.
Article
Immunology
Christa D. Jackson, Kinsey A. Hilliard, Charles R. Brown
Summary: The deficiency of 12/15-lipoxygenase (12/15-LO) exacerbates ankle swelling and arthritis severity in Lyme arthritis, suggesting that 12/15-LO lipid metabolites play a crucial role in resolving inflammatory arthritis. Therapeutic treatment with lipoxin A4 (LXA(4)) can alleviate joint edema and pain in Lyme arthritis patients.
FRONTIERS IN IMMUNOLOGY
(2023)
Meeting Abstract
Immunology
Christa D. Jackson, Charles R. Brown
JOURNAL OF IMMUNOLOGY
(2022)
Meeting Abstract
Immunology
Kinsey A. Hilliard, Charles R. Brown
JOURNAL OF IMMUNOLOGY
(2018)
Review
Biochemistry & Molecular Biology
Charles R. Brown, Edward A. Dennis
Article
Immunology
Carolyn A. Lacey, William J. Mitchell, Charles R. Brown, Jerod A. Skyberg
INFECTION AND IMMUNITY
(2017)
