Article
Surgery
Marie Bodilsen Nielsen, Jonathan Nortoft Dahl, Rasmus Laursen, Bente Jespersen, Per Ivarsen, Simon Winther, Henrik Birn
Summary: Kidney failure is linked to a higher risk of cardiovascular disease and death. This retrospective study examined the relationship between risk factors, coronary artery calcium score (CACS), coronary computed tomography angiography (CTA), major adverse cardiovascular events (MACE), and all-cause mortality in kidney transplant candidates. The presence of multiple risk factors, high CACS, and significant artery stenosis were found to predict MACE and mortality. In a subgroup undergoing both CACS and CTA, these imaging techniques provided additional information for predicting MACE.
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Article
Cardiac & Cardiovascular Systems
Martin Bodtker Mortensen, Sara Gaur, Attila Frimmer, Hans Erik Botker, Henrik Toft Sorensen, Kristian Hay Kragholm, Sand Ronnow Niels Peter, Flemming Hald Steffensen, Rebekka Vibjerg Jensen, Michael Maeng, Helle Kanstrup, Michael J. Blaha, Leslee J. Shaw, Omar Dzaye, Jonathon Leipsic, Bjarne Linde Norgaard, Jesper Moller Jensen
Summary: The diagnostic value of a 0 CAC score may vary with age, with smaller added diagnostic value for younger patients. In symptomatic patients under 60 years old, a significant proportion of obstructive CAD occurred in those without CAC and was associated with an increased risk of myocardial infarction and all-cause death.
Article
Cardiac & Cardiovascular Systems
Maria G. Hauge, Peter Damm, Klaus F. Kofoed, Anne S. Ersboll, Marianne Johansen, Per E. Sigvardsen, Mathias B. Moller, Andreas Fuchs, Jorgen T. Kuhl, Borge G. Nordestgaard, Lars Kober, Finn Gustafsson, Jesper J. Linde
Summary: This study found that younger women with previous preeclampsia had a slightly higher prevalence of coronary atherosclerosis compared to women from the general population. Preeclampsia remained an independent risk factor for coronary atherosclerosis after adjusting for traditional cardiovascular risk factors.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jona B. Krohn, Y. Nhi Nguyen, Mohammadreza Akhavanpoor, Christian Erbel, Gabriele Domschke, Fabian Linden, Marcus E. Kleber, Graciela Delgado, Winfried Maerz, Hugo A. Katus, Christian A. Gleissner
Summary: We identified four phenotypic subgroups of CAD bearing distinct demographic and biochemical characteristics with differences in prognosis, which may indicate multiple disease entities currently summarized as CAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Surgery
Geoffrey K. Dube, Ibrahim Batal, Lori Shah, Hilary Robbins, Selim M. Arcasoy, Syed Ali Husain
Summary: BKPyV and BK virus native kidney nephropathy (BKVN) are common after lung transplantation, with a frequency of 6% and 1.3%, respectively. Patients with a peak viral load ≥10,000 copies/mL have a higher incidence of end-stage kidney disease. Routine screening for BKPyV should be considered in all lung transplant recipients.
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Review
Cardiac & Cardiovascular Systems
Mina Ghobrial, Hazel Arfah Haley, Rebecca Gosling, Vignesh Rammohan, Patricia Lawford, D. Rod Hose, Julian P. Gunn, Paul D. Morris
Summary: Coronary angiography plays a crucial role in managing patients with chronic coronary syndromes, but there is debate over its potential replacement by CT angiography. Recently developed computational methods allow for virtual blood flow measurements, enhancing diagnostic accuracy and cost-effectiveness.
Article
Medicine, General & Internal
Thomas P. W. van den Boogert, Bimmer E. P. M. Claessen, Adrienne van Randen, Joost van Schuppen, S. Matthijs Boekholdt, Marcel A. M. Beijk, M. Karlijn Vrijmoeth, Jan Baan, M. Marije Vis, Jacobus A. Winkelman, Antoine H. G. Driessen, Jaap Stoker, R. Nils Planken, Jose P. Henriques
Summary: CTCA as an initial imaging modality is feasible to rule out CAD in patients awaiting non-coronary cardiac surgery, cardiomyopathy, heart failure, and ventricular arrhythmias, with only 17% requiring additional CAG after initial CTCA. Revascularization procedures were infrequently performed in both groups.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
David Feldman, Jacqueline Latina, Jana Lovell, Roger S. Blumenthal, Armin Arbab-Zadeh
Summary: The treatment of coronary artery disease focuses on managing symptoms and preventing cardiovascular events. Coronary CTA has emerged as the first line noninvasive imaging modality for evaluating coronary atherosclerosis, improving diagnostic accuracy and patient outcomes.
TRENDS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Multidisciplinary Sciences
Huaigang Chen, Bin Li, Yanyan Xiao, Hong Wang, Maobin Kuang, Hanjin Sun, Liu Yang
Summary: Coronary atherosclerotic heart disease is a serious disease and PCI is a common treatment. The OFR technique, which combines physiological assessment and high-definition imaging, shows promising diagnostic performance and good correlation with FFR.
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Lin, Liang Wang, Xiao-Na Zhang, Xiao Li, Jian Wang, Zhu-Jun Shen, Wei Chen, Zheng-Yu Jin, Yi-Ning Wang
Summary: This study evaluated the diagnostic performance of 1.5-T non-contrast MR coronary angiography for detecting coronary artery disease. The results showed that the combined use of whole-heart and volume-targeted imaging in MRCA can efficiently diagnose significant coronary stenosis with high sensitivity and moderate specificity.
EUROPEAN RADIOLOGY
(2021)
Review
Gastroenterology & Hepatology
Scott L. L. Friedman, Arun J. J. Sanyal
Summary: The field of hepatology has made significant progress in understanding liver function, genetic determinants of disease, antiviral therapy, and transplantation in the past 75 years. However, challenges such as fatty liver diseases, autoimmune disease, cancer, and pediatric liver disease still need to be addressed. Diagnostic advances are urgently needed to improve risk stratification and testing of new agents. Integrated care models should be extended to address systemic manifestations and comorbidities. Expansion of the workforce and incorporating emerging skills in data management and precision medicine are necessary. Continued investment in science is crucial for further progress.
Article
Medicine, General & Internal
Hytham Rashid, Jonathan Brown, Emily Nix, Alan Fisher Covin
Summary: This article discusses the diagnostic challenges of confusion symptoms in patients after coronary angiography and raises awareness for the possibility of contrast-induced encephalopathy.
CLINICAL CASE REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Hans Mickley, Karsten T. Veien, Oke Gerke, Jess Lambrechtsen, Allan Rohold, Flemming H. Steffensen, Mirza Husic, Dilek Akkan, Martin Busk, Louise B. Jessen, Lisette O. Jensen, Axel Diederichsen, Kristian A. Ovrehus
Summary: This study investigated the diagnostic and short-term role of FFRCT in chest pain patients with Agatston score (AS) > 399. The majority of patients had FFRCT <= 0.80, with the lowest FFRCT showing moderate diagnostic accuracy and specificity. Follow-up at 90 days showed correlation between FFRCT <= 0.80 and major clinical events.
JACC-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Muhummad Sohaib Nazir, Aurelien Bustin, Reza Hajhosseiny, Momina Yazdani, Matthew Ryan, Vittoria Vergani, Radhouene Neji, Karl P. Kunze, Edward Nicol, Pier Giorgio Masci, Divaka Perera, Sven Plein, Amedeo Chiribiri, Rene Botnar, Claudia Prieto
Summary: This study demonstrates the good diagnostic accuracy of high-resolution coronary cardiovascular magnetic resonance angiography (CCMRA) for detecting coronary artery disease (CAD). The sensitivity and negative predictive value are high, while the positive predictive value is moderate.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2022)
Article
Multidisciplinary Sciences
Cristoforo Simonetto, Susanne Rospleszcz, Jan Christian Kaiser, Kyoji Furukawa
Summary: This study aimed to estimate the large inter-individual heterogeneity in risk of coronary heart disease (CHD), which is only partially explained by traditional risk factors.
SCIENTIFIC REPORTS
(2022)