Targeting TIM-1 on CD4 T Cells Depresses Macrophage Activation and Overcomes Ischemia-Reperfusion Injury in Mouse Orthotopic Liver Transplantation

TIMgenes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

(2015) Gordon J. Freeman et al.   IMMUNOLOGICAL REVIEWS

Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice

(2012) Haofeng Ji et al.   LIVER TRANSPLANTATION

Interleukin-22

(2012) Paul J. Chestovich et al.   TRANSPLANTATION

Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate-Adaptive Immune-Mediated Tissue Inflammation

(2011) Y. Zhai et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

(2011) Qing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

The TIM-1:TIM-4 Pathway Enhances Renal Ischemia-Reperfusion Injury

(2011) S. Rong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

(2010) Feifan Zhou et al.   FEBS Journal

T-Cell Immunoglobulin Mucin-3 Determines Severity of Liver Ischemia/Reperfusion Injury in Mice in a TLR4-Dependent Manner

(2010) Yoichiro Uchida et al.   GASTROENTEROLOGY

Programmed death-1/B7-H1 negative costimulation protects mouse liver against ischemia and reperfusion injury

(2010) Haofeng Ji et al.   HEPATOLOGY

TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury

(2010) Yoshinori Yamanishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Cell Ig Domain and Mucin Domain 1 Engagement on Invariant NKT Cells in the Presence of TCR Stimulation Enhances IL-4 Production but Inhibits IFN-  Production

(2010) H. S. Kim et al.   JOURNAL OF IMMUNOLOGY

CD4 T cells promote tissue inflammation via CD40 signaling without de novo activation in a murine model of liver ischemia/reperfusion injury

(2009) Xiuda Shen et al.   HEPATOLOGY

The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse

(2009) Yoichiro Uchida et al.   HEPATOLOGY

Toll‐like receptors and adaptor molecules in liver disease: Update

(2008) Ekihiro Seki et al.   HEPATOLOGY

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model

(2008) Takuya Ueno et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunostimulatory Tim-1–specific antibody deprograms Tregs and prevents transplant tolerance in mice

(2008) Nicolas Degauque et al.   JOURNAL OF CLINICAL INVESTIGATION