Article
Biochemistry & Molecular Biology
Eloisa A. Vilas-Boas, Joao Victor Cabral-Costa, Vitor M. Ramos, Camille C. Caldeira da Silva, Alicia J. Kowaltowski
Summary: Calcium ions play a crucial role in regulating intracellular signaling pathways, metabolic control, and mitochondrial function. Mitochondria can buffer excess calcium and impact cytosolic calcium transients. Excessive calcium can be harmful, leading to mitochondrial dysfunction and cell death, while moderate calcium can activate mitochondrial enzymes and affect ATP production. This study investigates the quantitative effects of extracellular and intracellular calcium on oxidative phosphorylation in mouse liver mitochondria and intact liver cells. The findings suggest that specific concentrations of calcium activate oxidative phosphorylation, highlighting the Goldilocks effect of calcium on liver mitochondria.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2023)
Article
Psychology, Social
Sofie Dupre, Fien Heyde, Jasmine Vergauwe, Bart Wille
Summary: This study examines how people evaluate their conscientiousness levels and finds that the majority believe their conscientiousness is too high. By introducing a too little/too much response format, it reveals the ways in which individuals assess their conscientiousness levels.
PERSONALITY AND INDIVIDUAL DIFFERENCES
(2022)
Article
Medicine, General & Internal
Monica Livia Gheorghiu, Roxana Georgiana Bors, Ancuta-Augustina Gheorghisan-Galateanu, Anca Lucia Pop, Dragos Cretoiu, Valentin Nicolae Varlas
Summary: This retrospective study analyzed the treatment of hyperthyroidism in 36 pregnancies of 29 women and found that women with long-term antithyroid drug treatment before pregnancy had better control of thyroid function and fewer pregnancy and fetal complications compared to those diagnosed during pregnancy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Orthopedics
Stephen A. Hunt
Summary: Femoroacetabular impingement can cause hip pain and injuries, and it is important to carefully manage cam lesions to avoid overresection that may lead to poor outcomes. Intraoperative dynamic examination is crucial for recognizing and addressing this issue effectively.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2021)
Article
Criminology & Penology
Daniel P. Mears, Tiffaney A. Tomlinson, Jillian J. Turanovic
Summary: Studies show that both insufficient sleep and excessive sleep may be positively associated with delinquency, but the impact varies among different groups.
Article
Management
Emilio Pindado, Mercedes Sanchez, Marian Garcia Martinez
Summary: This study explores the relationship between agglomeration, entrepreneurs' resources and capabilities, and new ventures' innovativeness. The findings suggest that urban agglomeration has an inverted U-shaped effect on new ventures' innovativeness, and that entrepreneurs with higher levels of education or prior entrepreneurial experience are better able to benefit from agglomeration. Additionally, entrepreneurs in contact with other entrepreneurs are better positioned to deal with the externalities of agglomeration.
Review
Immunology
Judith F. Ashouri, Wan-Lin Lo, Trang T. T. Nguyen, Lin Shen, Arthur Weiss
Summary: ZAP70 plays a critical role in TCR signaling, and both hypoactive and hyperactive ZAP70 can lead to the development of autoimmune diseases. Normal ZAP70 function is crucial for the development of thymocytes and T cells, while abnormal ZAP70 function may disrupt key checkpoints for central tolerance development, increasing the chance of self-reactive T cells escaping negative selection.
IMMUNOLOGICAL REVIEWS
(2022)
Review
Endocrinology & Metabolism
A. B. Hansen, D. Wojdemann, C. H. Renault, A. T. Pedersen, K. M. Main, L. L. Raket, R. B. Jensen, A. Juul
Summary: This review covers the effects of sex steroids in adolescence, including scenarios of too little, too much, too late, and too early hormonal action. It discusses the etiology, signs and symptoms, differential diagnoses, long-term consequences, and treatment options for these hormonal disorders, as well as the use of exogenous sex steroids for therapeutic purposes in adolescents and young adults, such as gender-affirming therapy and hormone treatment for specific conditions.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Review
Immunology
Jose Manuel Martin-Villa, Christian Vaquero-Yuste, Marta Molina-Alejandre, Ignacio Juarez, Fabio Suarez-Trujillo, Adrian Lopez-Nares, Jose Palacio-Gruber, Luis Barrera-Gutierrez, Eduardo Fernandez-Cruz, Carmen Rodriguez-Sainz, Antonio Arnaiz-Villena
Summary: HLA-G is a non-classical HLA class I molecule with immunomodulatory properties that is involved in various processes such as organ transplantation, viral infections, cancer progression, and autoimmune diseases. Its immunosuppressive effect is exerted through interaction with its receptors on immune cells.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Daniele Mancardi, Sara Ottolenghi, Umberto Attanasio, Carlo Gabriele Tocchetti, Rita Paroni, Pasquale Pagliaro, Michele Samaja
Summary: Oxygen levels play a crucial role in regulating cellular processes and can affect cell death. Oscillating oxygen levels, rather than permanent low levels, are considered the most detrimental factor. The heart and brain are particularly sensitive to alterations in oxygen levels, and the interaction between oxygen and other gases such as nitric oxide is important in ischemic organs. Understanding the effects of oxygen dysregulation is also crucial for iron metabolism.
ANTIOXIDANTS & REDOX SIGNALING
(2022)
Article
Psychology, Multidisciplinary
Claudia Vogrincic-Haselbacher, Joachim I. Krueger, Brigitta Lurger, Isabelle Dinslaken, Julian Anslinger, Florian Caks, Arnd Florack, Hilmar Brohmer, Ursula Athenstaedt
Summary: When making online purchases, consumers are faced with a wealth of information, with varying degrees of willingness and ability to process it. Research shows that successful search strategies involve focused selection and processing of a moderate amount of information. Consumers can be categorized into three groups based on their information processing strategies, which also impact decision quality.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Medicine, Research & Experimental
Graeme Carrick-Ranson, Erin J. Howden, Benjamin D. Levine
Summary: The global aging population is leading to declines in physical function and an increased risk of chronic disease, but regular exercise can have positive effects on health and disease risk. Structured exercise training can improve cardiorespiratory fitness and muscular strength in the oldest old, enhancing physical function and independent living.
ANNUAL REVIEW OF MEDICINE
(2022)
Article
Economics
Ping Zou
Summary: Our study finds an inverted U-shaped relationship between corporate charitable giving and financial performance, suggesting that maintaining an appropriate level of charitable giving can maximize financial performance. Companies dynamically adjust their charitable giving to a set optimal level, which changes in response to the dynamic nature of the business environment. Additionally, privately owned firms can adjust their level of charitable giving faster than state-owned firms.
Review
Psychology, Multidisciplinary
Nadia M. Brashier
Summary: Conspiracy theories provide explanations for unethical events as intentional actions by powerful groups. People believe in secret plots due to disregarding accuracy, endorsing incompatible conspiracies, using heuristics, and holding irrational beliefs. Conspiracy theorists reject mainstream explanations and exhibit distrust, actively seeking 'evidence'. However, their search exposes them to misleading information and overestimation of knowledge. Understanding the negative consequences is crucial as conspiracy beliefs lead to political disengagement, environmental inaction, prejudice, and support for violence.
CURRENT OPINION IN PSYCHOLOGY
(2023)
Article
Economics
Jon Reiersen
Summary: This article compares survey data on individuals' awareness of income distribution in Norway and the United States, revealing that Norwegians tend to overestimate inequality while Americans greatly underestimate it. Interestingly, both groups construct ideal income distributions that closely resemble Norway's egalitarian distribution, indicating a possible influence of psychological capacity and actual income differences on their perceptions.
FORUM FOR SOCIAL ECONOMICS
(2022)
