Article
Radiology, Nuclear Medicine & Medical Imaging
Ariane Priscilla Magalhaes Tenorio, Jose Raniery Ferreira-Junior, Vitor Faeda Dalto, Matheus Calil Faleiros, Rodrigo Luppino Assad, Paulo Louzada-Junior, Marcello Henrique Nogueira-Barbosa, Rangaraj Mandayam Rangayyan, Paulo Mazzoncini de Azevedo-Marques
Summary: This article investigates MRI features correlated with spondyloarthritis and develops detection models for inflammatory sacroiliitis using different MRI techniques. The results show that the performance of these models is equivalent to that of specialists and can effectively identify inflammatory sacroiliitis.
JOURNAL OF DIGITAL IMAGING
(2022)
Article
Rheumatology
Sophie Hecquet, Jean-Philippe Lustig, Frank Verhoeven, Mickael Chouk, Sebastien Aubry, Daniel Wendling, Clement Prati
Summary: This study evaluated and compared the frequency and localization of inflammatory and structural lesions on MRIs of the sacroiliac joint in spondyloarthritis (SpA) and non-spondyloarthritis (non-SpA) patients. The results showed that inflammatory and structural lesions were mainly observed in SpA patients, while structural lesions were predominantly observed in non-SpA patients, with differences in localization.
THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE
(2022)
Article
Biology
Anca Emanuela Musetescu, Anca Bobirca, Florin Liviu Gherghina, Alesandra Florescu, Florin Bobirca, Paulina Lucia Ciurea, Cristina Criveanu, Alice Musca, Lucian Mihai Florescu, Ioana Andreea Gheonea
Summary: This study aimed to assess the performance of rheumatologists in interpreting inflammatory and structural damage to sacroiliac joints in axSpA patients, compared to radiologists. The results showed substantial agreement between senior and junior radiologists, as well as between senior radiologists and senior rheumatologists, while moderate agreement was observed with junior rheumatologists.
Article
Medicine, General & Internal
Paolo Falsetti, Edoardo Conticini, Carla Gaggiano, Caterina Baldi, Maria Tarsia, Marco Bardelli, Stefano Gentileschi, Roberto D'Alessandro, Suhel Gabriele Al Khayyat, Alessandra Cartocci, Claudia Fabiani, Luca Cantarini, Maria Antonietta Mazzei, Bruno Frediani
Summary: This study found that PDUS/SWA can be used to diagnose sacroiliitis in children, and RIs <0.55 have high specificity for this condition. Therefore, SIJs PDUS/SWA could be used as a screening method in children with suspected jSpA.
Article
Radiology, Nuclear Medicine & Medical Imaging
Anurag Gupta, Raghu Ratakonda, Girish Boraiah, Yin Xi, Avneesh Chhabra
Summary: In this study, single 3D isotropic magnetic resonance imaging was found to provide adequate assessment of sacroiliac joints in patients with suspected axial spondyloarthritis, demonstrating higher sensitivity and lower specificity for detecting active sacroiliitis. This is of importance for future screening of sacroiliitis and abdominopelvic enthesopathy.
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
(2022)
Article
Rheumatology
Katharina Ziegeler, Virginie Kreutzinger, Fabian Proft, Denis Poddubnyy, Kay Geert A. Hermann, Torsten Diekhoff
Summary: This study found that patients with mechanical joint disease had the highest proportion of atypical joints, with females showing significantly higher proportions than males, and symptomatic joint disease males having significantly higher proportions of atypical joints compared to controls.
Article
Rheumatology
Guillaume Marnas, Chloe Bernardy, Anthony Cole, Alexandre Bellier, Pierre Chapuis, Xavier Romand, Laure Gossec, Marie-Martine Lefevre-Colau, Violaine Foltz, Pascal Richette, Philippe Dieude, Anna Molto, Athan Baillet
Summary: This study investigated the association between bone marrow edema fulfilling the ASAS definition of MRI sacroiliitis and non-inflammatory spine abnormalities in patients with mechanical chronic back pain. The results showed a significant association between BME and non-inflammatory spine abnormalities.
Review
Physiology
Clement Prati, Thierry Lequerre, Benoit Le Goff, Bernard Cortet, Hechmi Toumi, Anne Tournadre, Hubert Marotte, Eric Lespessailles
Summary: A detailed anatomical description of the sacroiliac joint is crucial for understanding spondyloarthropathy, as sacroiliitis is its earliest and most common sign. Additionally, understanding the histopathology and immunological mechanisms of sacroiliac entheses is essential for comprehending the disease causation. This review focuses on the anatomical, histological, and immunohistological observations related to the development of sacroiliitis and discusses the sequencing of enthesitis, synovitis, and subchondral bone changes in spondyloarthropathy.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Keno K. Bressem, Lisa C. Adams, Fabian Proft, Kay Geert A. Hermann, Torsten Diekhoff, Laura Spiller, Stefan M. Niehues, Marcus R. Makowski, Bernd Hamm, Mikhail Protopopov, Valeria Rios Rodriguez, Hildurn Haibel, Judith Rademacher, Murat Torgutalp, Robert G. Lambert, Xenofon Baraliakos, Walter P. Maksymowych, Janis L. Vahldiek, Denis Poddubnyy
Summary: This study developed a deep neural network to detect changes in the sacroiliac joints indicative of axial spondyloarthritis on MRI. The results showed that the neural network had high accuracy in detecting inflammatory and structural changes.
Article
Immunology
Seulkee Lee, Uju Jeon, Ji Hyun Lee, Seonyoung Kang, Hyungjin Kim, Jaejoon Lee, Myung Jin Chung, Hoon-Suk Cha
Summary: An AI model was developed for detecting sacroiliitis in patients with axSpA using MRI, showing improved performance through the use of data augmentation and MIP techniques. The model has the potential to assist in wider clinical applications of MRI for axSpA diagnosis.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Rheumatology
M. Carotti, D. Benfaremo, M. Di Carlo, L. Ceccarelli, M. M. Luchetti, P. Piccinni, A. Giovagnoni, F. Salaffi
Summary: The study found that dual-energy computed tomography (DECT) had good diagnostic performance in evaluating the extent of bone marrow edema in patients with sacroiliitis associated with axial spondyloarthritis.
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ilkay Ergenc, Haluk Tarik Kani, Cemal Aydin Gundogmus, Rabia Ergelen, Naime Afsar Satis, Gazanfer Ekinci, Mehmet Pamir Atagunduz
Summary: This study investigates the value of reporting acute inflammatory and structural changes of the sacroiliac joint on magnetic resonance enterography (MRE) as auxiliary findings to aid in the diagnosis of axial spondyloarthritis. The study finds that in addition to intestinal findings, reporting these changes on MRE can alert physicians to the presence of previously undiagnosed axial spondyloarthritis.
Editorial Material
Rheumatology
Denis Poddubnyy, Torsten Diekhoff, Xenofon Baraliakos, Kay Geert A. Hermann, Joachim Sieper
Summary: This article discusses whether MRI can replace radiographs for diagnostic evaluation and classification of axial spondyloarthritis, and provides answers to specific questions based on current data.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Immunology
Liudan Tu, Churong Lin, Ya Xie, Xiaohong Wang, Qiujing Wei, Yanli Zhang, Jieruo Gu
Summary: This study found that patients with radiographic axial spondyloarthritis (r-axSpA) showed more active inflammatory and chronic structural damages on MRI compared to non-radiographic axial spondyloarthritis (nr-axSpA) patients, especially in terms of fat metaplasia and ankylosis.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Rheumatology
Xenofon Baraliakos, Anna Kuehn, Styliani Tsiami, Uta Kiltz, Martin Fruth, Juergen Braun
Summary: Age has different influences on the MRI lesions in the sacroiliac joints of patients with and without axial spondyloarthritis (axSpA). Bone marrow edema (BME) and erosions are more frequent in axSpA patients regardless of age, while fat lesions (FL) are only significantly different in patients over 50 years old.
Article
Surgery
H. Pelet, S. Tunon de Lara, C. Pfirrmann, P. Meynard, L. Harper, A. Angelliaume, X. Berard, Y. Lefevre
Summary: An 11-year-old boy presented with pain in the right knee, intermittent reverse ischemia of the right foot, and paraesthesia of the right toes. Imaging revealed a false aneurysm in the right superior popliteal artery and a singular osteochondroma in the posterior aspect of the distal femur. Two-stage surgeries were performed to excise the aneurysm and osteochondroma. At a 1-year follow-up, the patient was clinically well.
ACTA CHIRURGICA BELGICA
(2022)
Article
Orthopedics
Martin C. Berli, Kai Higashigaito, Tobias Gotschi, Christian W. A. Pfirrmann, Reto Sutter, Andrea B. Rosskopf
Summary: A new MRI scoring system (Balgrist Score) was developed for assessment of active Charcot foot with excellent interreader agreement. The Balgrist Score can help to identify patients requiring off-loading treatment for >= 90 days.
SKELETAL RADIOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Christian W. A. Pfirrmann
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Orthopedics
Christoph Germann, Daniela Kroismayr, Florian Brunner, Christian W. A. Pfirrmann, Reto Sutter, Veronika Zubler
Summary: Pregnancy and childbirth have no impact on long-term bone marrow edema in the sacroiliac joints, but may cause long-term subchondral sclerosis similar to that associated with spondyloarthritis. The number of children is positively correlated with sacroiliac joint sclerosis, while the birth method has no effect on sclerosis.
SKELETAL RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christoph Stern, Stefan Sommer, Christoph Germann, Julien Galley, Christian W. A. Pfirrmann, Benjamin Fritz, Reto Sutter
Summary: Ultra-low-dose CT with tin filtration for the osseous pelvis showed a significant dose reduction of 84% compared to standard CT, while maintaining similar imaging quality for assessing bone anatomy and pathologies. Additionally, ULD-CT demonstrated a markedly superior dose efficiency compared to standard CT.
EUROPEAN RADIOLOGY
(2021)
Article
Orthopedics
Franca K. Boldt, Benjamin Fritz, Patrick O. Zingg, Reto Sutter, Christian W. A. Pfirrmann
Summary: The femoral head defect is a common finding in MRI examinations of the hip, located in the anteroinferior aspect. There is no association with FAI, but patients with femoral head defects showed a slightly lower femoral antetorsion compared to those without defects.
SKELETAL RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tim Fischer, Christoph Stern, Benjamin Fritz, Patrick O. Zingg, Christian W. A. Pfirrmann, Reto Sutter
Summary: The study found that increased postoperative FA after THA was associated with MRI findings of acute as well as acute and chronic IFI. Findings of IFI were commonly seen in women.
Article
Radiology, Nuclear Medicine & Medical Imaging
Christoph Germann, Julien Galley, Anna L. Falkowski, Sandro F. Fucentese, Christian W. A. Pfirrmann, Daniel Nanz, Reto Sutter
Summary: 3D-DESS imaging at 7-T MRI offers significantly higher sensitivity in detecting chondral calcific deposits compared to 3-T MRI. Both readers showed significantly higher diagnostic confidence levels at 7 T compared to 3-T MRI and CT, with sharper delineation of chondral calcifications. Micro-CT in one patient suggested that 7-T MRI may potentially outperform standard CT in diagnosing chondral calcifications.
EUROPEAN RADIOLOGY
(2021)
Article
Orthopedics
Kai Higashigaito, Christian W. A. Pfirrmann, Sarah Koch, Dimitri Graf, Andreas Schweizer, Daniel Nanz, Andrea B. Rosskopf
Summary: The study evaluated the MRI anatomy of the STT ligament complex in asymptomatic and symptomatic individuals, showing that increased signal intensity of rpSTL is more frequent in patients with radial-sided wrist pain.
SKELETAL RADIOLOGY
(2022)
Article
Orthopedics
Julien Galley, Reto Sutter, Christoph Germann, Christian W. A. Pfirrmann
Summary: The presence of the Vulcan salute sign on conventional radiographs is specific for Morton's neuroma. The study also found significant differences in interphalangeal angles between patients with Morton's neuroma and controls, while there was no significant difference in intermetatarsal angle I/V between the groups. Interobserver agreement was substantial for the V-sign, and excellent for angle measurements.
SKELETAL RADIOLOGY
(2022)
Article
Orthopedics
B. Fritz, J. Fritz, S. F. Fucentese, C. W. A. Pfirrmann, R. Sutter
Summary: This study compared the quantification of femorotibial joint space using different imaging techniques, and found that weight-bearing cone beam CT combined with 3D-analysis allows for more detailed assessment of the joint space, demonstrating significantly more bone-on-bone appositions compared to weight-bearing conventional radiographs.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Orthopedics
Tina Passon, Christoph Germann, Benjamin Fritz, Christian Pfirrmann, Reto Sutter
Summary: The purpose of this study was to investigate the predictive value of talar head edema in acute ankle sprain for the presence of concomitant ligament injuries. The results showed that patients with talar head edema had more severe ligament injuries compared to patients without talar head edema. Talar head edema was associated with medial and lateral collateral ligament complex injuries, indicating severe ankle trauma.
SKELETAL RADIOLOGY
(2022)
Article
Orthopedics
Thorsten Jentzsch, Yann K. Meyer, Ines Unterfrauner, Andrea B. Rosskopf, Christian W. Pfirrmann, Patrick O. Zingg
Summary: This retrospective cohort study aimed to investigate the correlation between pain relief after injection and arthroplasty. The study included 88 patients who received intra-articular hip injection before primary total hip arthroplasty. Pain scores were compared at different stages, and it was found that the response to injection could predict pain relief after arthroplasty. The response to local anaesthetic in the diagnostic phase might be a better predictor than corticosteroids. Majority of patients with osteoarthritis can expect better pain relief after arthroplasty compared to the therapeutic phase after injection.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
Martin C. Berli, Nicolas Azaiez, Tobias Gotschi, Christian W. A. Pfirrmann, Ilker Uckay, Reto Sutter, Felix W. A. Waibel, Andrea B. Rosskopf
Summary: This study evaluated the distribution and severity of muscle atrophy in diabetic patients with active Charcot foot (CF) compared to those without CF, and correlated the muscle atrophy with the severity of CF disease.
SKELETAL RADIOLOGY
(2023)
Article
Orthopedics
Christoph Germann, Lukas Filli, Pia M. Jungmann, Dimitri N. Graf, Jan Fritz, Christian W. A. Pfirrmann, Reto Sutter
Summary: This study found that bone marrow edema and periosteal edema are common around the femoral stem in the first 6 months after total hip arthroplasty (THA), but decrease significantly after 12 months. Soft tissue edema along the surgical access route disappears by 12 months postoperatively.
SKELETAL RADIOLOGY
(2021)