IL-17A Induces Signal Transducers and Activators of Transcription–6–Independent Airway Mucous Cell Metaplasia

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

The effects of an anti–IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

(2011) Grant C. Nicholson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production

(2011) Dawn C. Newcomb et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-13 Regulates Th17 Secretion of IL-17A in an IL-10-Dependent Manner

(2011) D. C. Newcomb et al.   JOURNAL OF IMMUNOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized, Controlled, Phase 2 Study of AMG 317, an IL-4Rα Antagonist, in Patients with Asthma

(2010) Jonathan Corren et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma

(2010) Gail M. Gauvreau et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma

(2010) Dave Singh et al.   BMC Pulmonary Medicine

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

A Functional IL-13 Receptor Is Expressed on Polarized Murine CD4+ Th17 Cells and IL-13 Signaling Attenuates Th17 Cytokine Production

(2009) D. C. Newcomb et al.   JOURNAL OF IMMUNOLOGY

YM-341619 suppresses the differentiation of spleen T cells into Th2 cells in vitro, eosinophilia, and airway hyperresponsiveness in rat allergic models

(2008) Keiko Ohga et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Interleukin-17 Receptor Plays a Gender-Dependent Role in Host Protection against Porphyromonas gingivalis-Induced Periodontal Bone Loss

(2008) J. J. Yu et al.   INFECTION AND IMMUNITY

Increased sputum and bronchial biopsy IL-13 expression in severe asthma

(2008) Shironjit K. Saha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY