Epigenetic Regulation of Tolerance to Toll-Like Receptor Ligands in Alveolar Epithelial Cells

Epigenetic targets for novel therapies of lung diseases

(2015) Brian S. Comer et al.   PHARMACOLOGY & THERAPEUTICS

Expression of toll-like receptor 2 and 4 is increased in the respiratory epithelial cells of chronic idiopathic interstitial pneumonia patients

(2014) Heounjeong Go et al.   RESPIRATORY MEDICINE

Epigenetic upregulation of CCL2 and CCL3 via histone modifications in infiltrating macrophages after peripheral nerve injury

(2013) Norikazu Kiguchi et al.   CYTOKINE

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

(2013) M. Shan et al.   SCIENCE

Differential microRNA (miRNA) expression could explain microbial tolerance in a novel chronic peritonitis model

(2012) Ziad Kanaan et al.   Innate Immunity

TLR Signaling Prevents Hyperoxia-Induced Lung Injury by Protecting the Alveolar Epithelium from Oxidant-Mediated Death

(2012) M. N. Ballinger et al.   JOURNAL OF IMMUNOLOGY

DOK3 Negatively Regulates LPS Responses and Endotoxin Tolerance

(2012) Qisheng Peng et al.   PLoS One

MicroRNA in TLR signaling and endotoxin tolerance

(2011) Md A Nahid et al.   Cellular & Molecular Immunology

Epigenetic regulation of immune cell functions during post-septic immunosuppression

(2011) William F. Carson et al.   Epigenetics

Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases

(2011) Laurence Macia et al.   IMMUNOLOGICAL REVIEWS

Toll like receptors in diseases of the lung

(2011) Melissa A. Kovach et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20

(2011) Yanbao Xiong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Epigenetics Underpinning the Regulation of the CXC (ELR+) Chemokines in Non-Small Cell Lung Cancer

(2011) Anne-Marie Baird et al.   PLoS One

Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

(2011) Andrew J. Thorley et al.   PLoS One

Endotoxin tolerance and cross-tolerance in mast cells involves TLR4, TLR2 and FcεR1 interactions and SOCS expression: perspectives on immunomodulation in infectious and allergic diseases

(2010) Saulo F Saturnino et al.   BMC INFECTIOUS DISEASES

Mechanisms of tolerance and allergic sensitization in the airways and the lungs

(2010) Maria A Curotto de Lafaille et al.   CURRENT OPINION IN IMMUNOLOGY

Gut Microbiota and Probiotics in Modulation of Epithelium and Gut-Associated Lymphoid Tissue Function

(2010) Yolanda Sanz et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling

(2010) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

Induction of innate immune response and absence of subsequent tolerance to dsRNA in biliary epithelial cells relate to the pathogenesis of biliary atresia

(2010) Kenichi Harada et al.   LIVER INTERNATIONAL

IRAK-M Regulates Chromatin Remodeling in Lung Macrophages during Experimental Sepsis

(2010) Kenneth Lyn-Kew et al.   PLoS One

A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation

(2009) N. Oshima et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Development of endotoxin tolerance in humans in vivo

(2009) Annelies Draisma et al.   CRITICAL CARE MEDICINE

In Vivo Lipopolysaccharide Exposure of Human Blood Leukocytes Induces Cross-Tolerance to Multiple TLR Ligands

(2009) A. F. de Vos et al.   JOURNAL OF IMMUNOLOGY

Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling

(2009) Wenji Piao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells

(2009) Eloïse Raoust et al.   PLoS One

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Language: Disputed definitions

(2008)   NATURE