Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice

Caveolin-1, cellular senescence and pulmonary emphysema

(2016) Daniela Volonte et al.   Aging-US

Cellular senescence increases expression of bacterial ligands in the lungs and is positively correlated with increased susceptibility to pneumococcal pneumonia

(2011) Pooja Shivshankar et al.   AGING CELL

Activation of nuclear factor-kappa B signalling promotes cellular senescence

(2011) E Rovillain et al.   ONCOGENE

Age-associated increase in heterochromatic marks in murine and primate tissues

(2010) Jill A. Kreiling et al.   AGING CELL

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells

(2010) Shunsuke Minagawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Diminished Prostaglandin E2Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis

(2010) Toby M. Maher et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells

(2010) Guillaume Voghel et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

(2009) J. N. Bartholomew et al.   CANCER RESEARCH

A comparative analysis of the cell biology of senescence and aging

(2009) Eun Seong Hwang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

COPD as a Disease of Accelerated Lung Aging

(2009) Kazuhiro Ito et al.   CHEST

Bleomycin and its Role in Inducing Apoptosis and Senescence in Lung Cells - Modulating Effects of Caveolin-1

(2009) Michael Kasper et al.   CURRENT CANCER DRUG TARGETS

Use of Senescence-Accelerated Mouse Model in Bleomycin-Induced Lung Injury Suggests That Bone Marrow-Derived Cells Can Alter the Outcome of Lung Injury in Aged Mice

(2009) J. Xu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Alveolar Cell Senescence Exacerbates Pulmonary Inflammation in Patients with Chronic Obstructive Pulmonary Disease

(2009) Takao Tsuji et al.   RESPIRATION

Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo

(2008) Elena Tourkina et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The role of caveolin-1 in pulmonary matrix remodeling and mechanical properties

(2008) O. Le Saux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Reparative Capacity of Airway Epithelium Impacts Deposition and Remodeling of Extracellular Matrix

(2008) Joshua C. Snyder et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Caveolin-1, transforming growth factor-β receptor internalization, and the pathogenesis of systemic sclerosis

(2008) Francesco Del Galdo et al.   CURRENT OPINION IN RHEUMATOLOGY

Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H2O2-induced premature senescence and interplay with p38αMAPK

(2008) Aline Chrétien et al.   FEBS LETTERS

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2

(2007) Dianne M. Walters et al.   ANTIOXIDANTS & REDOX SIGNALING

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY