Allergic Lung Inflammation Is Mediated by Soluble Tumor Necrosis Factor (TNF) and Attenuated by Dominant-Negative TNF Biologics

Narrative Review: The Role of Th2 Immune Pathway Modulation in the Treatment of Severe Asthma and Its Phenotypes

(2013) Stewart J. Levine   ANNALS OF INTERNAL MEDICINE

Soluble TNF, but not membrane TNF, is critical in LPS-induced hepatitis

(2010) Maria L. Olleros et al.   JOURNAL OF HEPATOLOGY

A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-α Blockade in Severe Persistent Asthma

(2009) Sally E. Wenzel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor

(2009) Zehra Kaymakcalan et al.   CLINICAL IMMUNOLOGY

Dominant‐Negative Tumor Necrosis Factor Protects fromMycobacterium bovisBacillus Calmette‐Guérin (BCG) and Endotoxin‐Induced Liver Injury without Compromising Host Immunity to BCG andMycobacterium tuberculosis

(2009) Maria L. Olleros et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced byLeishmania major infection

(2008) Cindy Allenbach et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protective role of membrane tumour necrosis factor in the host’s resistance to mycobacterial infection

(2008) Nasiema Allie et al.   IMMUNOLOGY

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

(2008) Melissa K McCoy et al.   MOLECULAR THERAPY

Breast milk–mediated transfer of an antigen induces tolerance and protection from allergic asthma

(2008) Valérie Verhasselt et al.   NATURE MEDICINE

Targeting TNF-α: A novel therapeutic approach for asthma

(2007) Christopher Brightling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

(2007) Daniel Tracey et al.   PHARMACOLOGY & THERAPEUTICS