An Aberrant Leukotriene A4Hydrolase–Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease

A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation

(2014) A. Gaggar et al.   JOURNAL OF IMMUNOLOGY

Mortality by Level of Emphysema and Airway Wall Thickness

(2013) Ane Johannessen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette Smoke-Induced Collagen Destruction; Key to Chronic Neutrophilic Airway Inflammation?

(2013) Saskia A. Overbeek et al.   PLoS One

Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells

(2012) Nadia Moretto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Update in Chronic Obstructive Pulmonary Disease in 2010

(2011) MeiLan K. Han   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in mice

(2010) M. A. Hassan Talukder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown

(2010) Saskia Braber et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Determination of acrolein and other carbonyls in cigarette smoke using coupled silica cartridges impregnated with hydroquinone and 2,4-dinitrophenylhydrazine

(2010) Shigehisa Uchiyama et al.   JOURNAL OF CHROMATOGRAPHY A

A Critical Role for LTA4H in Limiting Chronic Pulmonary Neutrophilic Inflammation

(2010) R. J. Snelgrove et al.   SCIENCE

Leukotriene B 4 Contributes to Exhaled Breath Condensate and Sputum Neutrophil Chemotaxis in COPD

(2009) Jean-Louis Corhay et al.   CHEST

Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen

(2009) Philip J. O'Reilly et al.   JOURNAL OF NEUROIMMUNOLOGY

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)

(2008) J. Vestbo et al.   EUROPEAN RESPIRATORY JOURNAL

Acrolein-Activated Matrix Metalloproteinase 9 Contributes to Persistent Mucin Production

(2007) Hitesh S. Deshmukh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY