Article
Multidisciplinary Sciences
Preetish Kadur Lakshminarasimha Murthy, Vishwaraj Sontake, Aleksandra Tata, Yoshihiko Kobayashi, Lauren Macadlo, Kenichi Okuda, Ansley S. Conchola, Satoko Nakano, Simon Gregory, Lisa A. Miller, Jason R. Spence, John F. Engelhardt, Richard C. Boucher, Jason R. Rock, Scott H. Randell, Purushothama Rao Tata
Summary: This study identifies previously unknown cell types in the human distal airways and reveals their roles in lung development and regeneration. These findings are important for understanding the mechanisms underlying respiratory diseases.
Review
Respiratory System
Kirsty L. Bradley, Clare A. Stokes, Stefan J. Marciniak, Lisa C. Parker, Alison M. Condliffe
Summary: The lungs are exposed to various environmental toxins and pathogens, leading to respiratory diseases associated with hypoxia. Endoplasmic reticulum stress can be triggered by these factors, activating the unfolded protein response. This response plays a significant role in the pathogenesis and progression of respiratory diseases, making it a potential target for therapeutic interventions.
Article
Pediatrics
Godwill Azeh Engwa, Chungag Anye, Benedicta Ngwenchi Nkeh-Chungag
Summary: This study found an association between obesity and airway obstruction in South African adolescents of African ancestry, suggesting that obese adolescents are more likely to have impaired lung function.
Review
Allergy
Nur Sabrina Idrose, E. Haydn Walters, Jingwen Zhang, Don Vicendese, Ed J. Newbigin, Jo A. Douglass, Bircan Erbas, Adrian J. Lowe, Jennifer L. Perret, Caroline J. Lodge, Shyamali C. Dharmage
Summary: Outdoor pollen exposure is associated with type-2 airway inflammation in both the upper and lower airways, with little evidence of lung function changes. Seasonal pollen, eosinophilia, and ECP levels may be related to allergic rhinitis, but results vary between studies. Eosinophilic airway inflammation due to outdoor pollen exposure may increase with age in susceptible individuals with asthma and allergic rhinitis.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Article
Veterinary Sciences
Roxane Westerfeld, Flavie Payette, Valerie Dubuc, Estelle Manguin, Khristine Picotte, Guy Beauchamp, Christian Bedard, Mathilde Leclere
Summary: Soaked hay can help control airway obstruction in horses with severe asthma. However, the strict protocol for soaking and discarding dried-out hay used in this study may be considered inconvenient by horse owners.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2023)
Article
Allergy
Kathryn G. Welsh, Karl A. Holden, Andrew J. Wardlaw, Jack Satchwell, William Monteiro, Catherine H. Pashley, Erol A. Gaillard
Summary: The study revealed that a significant proportion of children with asthma are sensitized to thermotolerant fungi, leading to poorer lung function and increased need for systemic corticosteroids. Additionally, filamentous fungi were found in sputum during asthma attacks, suggesting a potential association between fungal presence and acute asthma exacerbations.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Article
Pediatrics
Manisha Ramphul, Kathryn G. Welsh, Richard D. May, Michael A. Ghebre, Laura Rapley, Emma Suzanne Cohen, Athula Herath, William Monteiro, Karine Rousseau, David J. Thornton, Christopher E. Brightling, Erol A. Gaillard
Summary: The study found that sputum mediator profiles consistent with bacterial and viral respiratory infections, as well as T2 inflammation markers, co-exist in children with acute severe asthma attacks.
Article
Emergency Medicine
Osman Adi, Muhammad Faiz Baherin, Chan Pei Fong, Ahmad AbdulBasitz Ahmad Fatan, Azma Haryaty Ahmad, Alhady Alfian Yusof, Faheem Ahmed Khan
Summary: This article reports three cases of cardiac arrest due to foreign body airway obstruction (FBAO), where prompt flexible bronchoscopy was performed to confirm the diagnosis and retrieve the foreign body, leading to immediate improvements in oxygenation and ventilation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Jonghae Kim, Bum Young Park, Jung A. Lim
Summary: Awake bronchoscopy-guided intubation is a safe method for airway management in patients with endotracheal masses. Close cooperation between anesthesiologists and surgeons, as well as preoperative preparation for airway management, are essential. It is important to have alternative plans in place in case intubation and ventilation are not possible.
Review
Immunology
Yunhong Yu, Zhengqiu Lian
Summary: Transfusion-related acute lung injury (TRALI) is a severe adverse event and a leading cause of transfusion-associated death. Effective management strategies for the prevention and treatment of associated lung edema are urgently needed. Recent studies have advanced our understanding of TRALI pathogenesis and led to a decrease in TRALI-associated morbidity.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Clinical Neurology
Fiona L. Knapman, E. Myfanwy Cohen, Tom Kulaga, Nigel Lovell, Leszek Lisowski, Simon Mcmullan, Peter G. R. Burke, Lynne E. Bilston
Summary: This study proposes a novel optogenetics-based therapy for obstructive sleep apnea (OSA) and demonstrates its feasibility using a rodent model. The therapy involves stimulating upper airway muscle contractions in response to light. The results show that muscle-specific promoter-driven optogenetic muscle activation can effectively restore muscle activity and induce airway dilation.
Review
Medicine, General & Internal
Chaitanya Gadepalli, Karolina M. Stepien, Reena Sharma, Ana Jovanovic, Govind Tol, Andrew Bentley
Summary: This study reviewed 31 adult MPS patients, proposing a Salford Mucopolysaccharidosis Airway Score (SMAS) to assess the severity of airway disease. It was found that an SMAS score above 25 may predict difficult airways and potential complications.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Computer Science, Information Systems
Chang Sheng Lee, Yaolong Lou, Minghui Li, Qammer H. Abbasi, Muhammad Ali Imran
Summary: This study presents a new and effective method for assessing lung function using acoustic imaging, which links acoustic lung images with pathologic changes. It also analyzes the practicality and extreme design of the acoustic imaging system on the resolution of the located nidus. The research may be used to offer recommendations for acoustic imaging system design and assess the number of sensors in current systems.
Article
Multidisciplinary Sciences
Hua Kui, Bo Ran, Maosen Yang, Xin Shi, Yingyu Luo, Yujie Wang, Tao Wang, Diyan Li, Surong Shuai, Mingzhou Li
Summary: Chickens are important sources of protein for human diet and are used in biomedical research. The skeletal muscles of chickens have diverse origins, shapes, metabolic features, and physical functions, making increasing meat production a key goal in the poultry industry. Previous gene expression studies have overlooked the differences among various types of skeletal muscles. In this study, the researchers sequenced 58 samples from 10 different skeletal muscles of White Plymouth Rock chickens and generated a comprehensive transcriptional map, providing valuable information on muscle fiber characteristics.
Article
Plant Sciences
Ibrahim Sulaiman, Emmanuel Oshiogwe Okwuofu, Norhafizah Mohtarrudin, Jonathan Chee Woei Lim, Johnson Stanslas
Summary: The standardized Andrographis paniculata 50% ethanol extract (APEE50) showed anti-inflammatory effects in a mouse asthma model by down-regulating Th2 cytokine gene expression and oxidative stress levels.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Dominique Hansen, Paul Dendale, Karin Coninx, Luc Vanhees, Massimo F. Piepoli, Josef Niebauer, Veronique Cornelissen, Roberto Pedretti, Eva Geurts, Gustavo R. Ruiz, Ugo Corra, Jean-Paul Schmid, Eugenio Greco, Constantinos H. Davos, Frank Edelmann, Ana Abreu, Bernhard Rauch, Marco Ambrosetti, Simona S. Braga, Olga Barna, Paul Beckers, Maurizio Bussotti, Robert Fagard, Pompilio Faggiano, Esteban Garcia-Porrero, Evangelia Kouidi, Michel Lamotte, Daniel Neunhaeuserer, Rona Reibis, Martijn A. Spruit, Christoph Stettler, Tim Takken, Cajsa Tonoli, Carlo Vigorito, Heinz Voeller, Patrick Doherty
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2017)
Review
Sport Sciences
Dominique Hansen, Josef Niebauer, Veronique Cornelissen, Olga Barna, Daniel Neunhaeuserer, Christoph Stettler, Cajsa Tonoli, Eugenio Greco, Robert Fagard, Karin Coninx, Luc Vanhees, Massimo F. Piepoli, Roberto Pedretti, Gustavo Rovelo Ruiz, Ugo Corra, Jean-Paul Schmid, Constantinos H. Davos, Frank Edelmann, Ana Abreu, Bernhard Rauch, Marco Ambrosetti, Simona Sarzi Braga, Paul Beckers, Maurizio Bussotti, Pompilio Faggiano, Esteban Garcia-Porrero, Evangelia Kouidi, Michel Lamotte, Rona Reibis, Martijn A. Spruit, Tim Takken, Carlo Vigorito, Heinz Voeller, Patrick Doherty, Paul Dendale
Article
Physiology
J. F. Argacha, O. Xhaet, M. Gujic, G. De Boeck, C. Dreyfuss, M. Lamotte, D. Adamopoulos, P. van de Borne
Article
Critical Care Medicine
Vitalie Faoro, Saskia Boldingh, Mickael Moreels, Sarah Martinez, Michel Lamotte, Philippe Unger, Serge Brimioulle, Sandrine Huez, Robert Naeije
Article
Cardiac & Cardiovascular Systems
Michel Lamotte, Fany Fleury, Melissa Pirard, Alexander Jamon Philippe, Philippe van de Borne
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
(2010)
Article
Respiratory System
R. Naeije, S. Huez, M. Lamotte, K. Retailleau, S. Neupane, D. Abramowicz, V. Faoro
EUROPEAN RESPIRATORY JOURNAL
(2010)
Article
Respiratory System
Gael Deboeck, Cristina Scoditti, Sandrine Huez, Jean-Luc Vachiery, Michel Lamotte, Linda Sharples, Christian Melot, Robert Naeije
EUROPEAN RESPIRATORY JOURNAL
(2012)
Article
Physiology
Vitalie Faoro, Sandrine Huez, Rebecca Vanderpool, Herman Groepenhoff, Claire de Bisschop, Jean-Benoit Martinot, Michel Lamotte, Adriana Pavelescu, Herve Guenard, Robert Naeije
JOURNAL OF APPLIED PHYSIOLOGY
(2014)
Article
Sport Sciences
Kevin Forton, Michel Lamotte, Alexis Gillet, Martin Chaumont, Philippe van de Borne, Vitalie Faoro
Summary: The results of this study suggest that a single dose of bisoprolol does not affect metabolism, respiratory response, and exercise capacity. However, beta-adrenergic blocker dose-dependently reduces exercise hemodynamic response by lowering blood pressure and the chronotropic response.
SPORTS MEDICINE-OPEN
(2022)
Article
Cardiac & Cardiovascular Systems
Alexis Gillet, Michel Lamotte, Kevin Forton, Ana Roussoulieres, Celine Dewachter, Jason Bouziotis, Gael Deboeck, Philippe van de Borne
Summary: The purpose of this study was to compare the effectiveness of three different resistance training methods for cardiac rehabilitation. The results showed that these methods induced similar increases in peak heart rate and blood pressure, with the RISE and DROP methods being more efficient in terms of training volume and time. These findings have important implications for the selection and design of cardiac rehabilitation training.
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2023)
Article
Cardiac & Cardiovascular Systems
G. Deboeck, M. Vicenzi, M. Lamotte, V. Faoro
Summary: This study evaluated the aerobic capacity of obese individuals and found that both those with and without metabolic syndrome had normal aerobic profiles. VO2peak divided by body weight (BMI24) can be used as a meaningful index of aerobic capacity in obese patients.
RESPIRATORY MEDICINE
(2023)
Article
Health Care Sciences & Services
Clara Douin, Kevin Forton, Michel Lamotte, Alexis Gillet, Philippe van de Borne
Summary: The study aimed to evaluate the benefits of cardio-pulmonary rehabilitation for severe to moderate COVID-19 patients. The findings showed that rehabilitation training can improve the physical capacity and reduce exercise hyperventilation in COVID-19 patients, although it is not the sole factor for their partial recovery.
Article
Psychology, Multidisciplinary
Batsele Elise, Sophie Vanden Eynde, Nathalie Egee, Michel Lamotte, Philippe Van de Borne, Fantini-Hauwel Carole
Summary: This study found that low trait emotional competencies score may predict the persistence of depression symptoms in coronary heart disease patients, while unexpectedly, high score of trait emotional competencies was also associated with withdrawal from cardiac rehabilitation. Heart rate variability did not predict the persistence of depression or anxiety symptoms, and was not associated with trait emotional competencies, suggesting the need for future research in this area.
PSYCHOLOGICAL REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Michel X. Lamotte, Sara Chimenti, Gael Deboeck, Alexis Gillet, Raymond Kacelenenbogen, Jonathan Strapart, Frederic Vandeneynde, Guido Van Nooten, Martine Antoine