Tolerance Induction at the Early Maternal-Placental Interface Through Selective Cell Recruitment and Targeting by Immune Polypeptides

Evidence for a Selective Migration of Fetus-Specific CD4+CD25bright Regulatory T Cells from the Peripheral Blood to the Decidua in Human Pregnancy

(2014) T. Tilburgs et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Vasoactive Intestinal Peptide (VIP) Induces Differentiation of Th17 Cells with a Distinctive Cytokine Profile

(2014) M. Yadav et al.   JOURNAL OF IMMUNOLOGY

Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1

(2012) Anthony J Harmar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Defects in the vasoactive intestinal peptide (VIP)/VPAC system during early stages of the placental-maternal leucocyte interaction impair the maternal tolerogenic response

(2012) L. Fraccaroli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss

(2012) R. E. Ramhorst et al.   GLYCOBIOLOGY

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

(2012) Gabriel A. Rabinovich et al.   IMMUNITY

Blockage of Heme Oxygenase-1 Abrogates the Protective Effect of Regulatory T Cells on Murine Pregnancy and Promotes the Maturation of Dendritic Cells

(2012) Anne Schumacher et al.   PLoS One

Chemokine Gene Silencing in Decidual Stromal Cells Limits T Cell Access to the Maternal-Fetal Interface

(2012) P. Nancy et al.   SCIENCE

Modulation and Recruitment of Inducible Regulatory T Cells by First Trimester Trophoblast Cells

(2011) Rosanna Ramhorst et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

RNA sensors in human osteoarthritis and rheumatoid arthritis synovial fibroblasts: Immune regulation by vasoactive intestinal peptide

(2011) Mar Carrión et al.   ARTHRITIS AND RHEUMATISM

VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins

(2011) Alain Couvineau et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chemokines in health and disease

(2011) Dayanidhi Raman et al.   EXPERIMENTAL CELL RESEARCH

Gimme shelter: the immune system during pregnancy

(2011) Alba Munoz-Suano et al.   IMMUNOLOGICAL REVIEWS

Effect of VIP on the balance between cytokines and master regulators of activated helper T cells

(2011) Rebeca Jimeno et al.   IMMUNOLOGY AND CELL BIOLOGY

Absence of Vasoactive Intestinal Peptide Expression in Hematopoietic Cells Enhances Th1 Polarization and Antiviral Immunity in Mice

(2011) J.-M. Li et al.   JOURNAL OF IMMUNOLOGY

A balancing act: mechanisms by which the fetus avoids rejection by the maternal immune system

(2011) J C Warning et al.   REPRODUCTION

Galectins: guardians of eutherian pregnancy at the maternal–fetal interface

(2011) Nandor Gabor Than et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Governing the Invasive Trophoblast: Current Aspects on Intra- and Extracellular Regulation

(2010) Justine S. Fitzgerald et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Contribution of Macrophages to Normal and Pathological Pregnancies

(2010) Takeshi Nagamatsu et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Regulatory T Cells and Their Role in Pregnancy

(2010) Anne Leber et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immunology of Pre-Eclampsia

(2010) Christopher W. G. Redman et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Immune System in Pregnancy: A Unique Complexity

(2010) Gil Mor et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Th1/Th2/Th17 and Regulatory T-Cell Paradigm in Pregnancy

(2010) Shigeru Saito et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Modulation of Maternal LIF Producers T Cells by Trophoblast and Paternal Antigens

(2010) Laura Fraccaroli et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Asthma and pulmonary arterial hypertension: do they share a key mechanism of pathogenesis?

(2010) S. I. Said et al.   EUROPEAN RESPIRATORY JOURNAL

Endoglandular trophoblast, an alternative route of trophoblast invasion? Analysis with novel confrontation co-culture models

(2010) G. Moser et al.   HUMAN REPRODUCTION

New insights into the role of VIP on the ratio of T-cell subsets during the development of autoimmune diabetes

(2010) Rebeca Jimeno et al.   IMMUNOLOGY AND CELL BIOLOGY

Human Decidual Tissue Contains Differentiated CD8+ Effector-Memory T Cells with Unique Properties

(2010) T. Tilburgs et al.   JOURNAL OF IMMUNOLOGY

Invasion of the leukocytes into the fetal-maternal interface during pregnancy

(2010) Nardhy Gomez-Lopez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Modulation of macrophage inflammatory profile in pregnant nonobese diabetic (NOD) mice

(2010) Luciana Larocca et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dendritic Cells Transduced With Lentiviral Vectors Expressing VIP Differentiate Into VIP-secreting Tolerogenic-like DCs

(2010) Miguel G Toscano et al.   MOLECULAR THERAPY

IFPA Gabor Than Award lecture: Transformation of the spiral arteries in human pregnancy: Key events in the remodelling timeline

(2010) L.K. Harris   PLACENTA

LIM and SH3 Protein -1 Modulates CXCR2-Mediated Cell Migration

(2010) Dayanidhi Raman et al.   PLoS One

REVIEW ARTICLE: Inflammation and Implantation

(2009) Nava Dekel et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Vasoactive Intestinal Peptide-Mediated Th17 Differentiation

(2009) Mahesh Yadav et al.   Annals of the New York Academy of Sciences

FOXP3+ Regulatory T Cells and T Helper 1, T Helper 2, and T Helper 17 Cells in Human Early Pregnancy Decidua1

(2009) Jenny Mjösberg et al.   BIOLOGY OF REPRODUCTION

VIP modulates the pro-inflammatory maternal response, inducing tolerance to trophoblast cells

(2009) Laura Fraccaroli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the Protean Effects of “Selective” Antagonists

(2009) Denis Sohy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis

(2009) N. F. Neel et al.   JOURNAL OF CELL SCIENCE

Systemic Reduction of Functionally Suppressive CD4dimCD25highFoxp3+ Tregs in Human Second Trimester Pregnancy Is Induced by Progesterone and 17 -Estradiol

(2009) J. Mjosberg et al.   JOURNAL OF IMMUNOLOGY

Induction of Alloantigen-Specific Human T Regulatory Cells by Vasoactive Intestinal Peptide

(2009) D. Pozo et al.   JOURNAL OF IMMUNOLOGY

Villitis of Unknown Etiology Is Associated with a Distinct Pattern of Chemokine Up-Regulation in the Feto-Maternal and Placental Compartments: Implications for Conjoint Maternal Allograft Rejection and Maternal Anti-Fetal Graft-versus-Host Disease

(2009) M. J. Kim et al.   JOURNAL OF IMMUNOLOGY

Recurrent pregnancy loss: A disease of inflammation and coagulation

(2009) Joanne Kwak-Kim et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

(2009) Juan M Ilarregui et al.   NATURE IMMUNOLOGY

The Isolation and Characterization of a Novel Telomerase Immortalized First Trimester Trophoblast Cell Line, Swan 71

(2009) S.L. Straszewski-Chavez et al.   PLACENTA

Potential immunomodulatory role of VIP in the implantation sites of prediabetic nonobese diabetic mice

(2009) Valeria Roca et al.   REPRODUCTION

A potential tolerogenic immune mechanism in a trophoblast cell line through the activation of chemokine-induced T cell death and regulatory T cell modulation

(2008) L. Fraccaroli et al.   HUMAN REPRODUCTION

Regardless of genotype, offspring of VIP-deficient female mice exhibit developmental delays and deficits in social behavior

(2008) Maria A. Lim et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Severe preeclampsia is characterized by increased placental expression of galectin-1

(2008) Nandor Gabor Than et al.   Journal of Maternal-Fetal & Neonatal Medicine

Orchestrating the orchestrators: chemokines in control of T cell traffic

(2008) Shannon K Bromley et al.   NATURE IMMUNOLOGY

Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications

(2008) Satomi Onoue et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

(2008) J. E. Mold et al.   SCIENCE