Somatic thrombopoietin (THPO) gene mutations in childhood myeloid leukemias

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group

(2013) E. A. Coenen et al.   BLOOD

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

(2013) I. Roberts et al.   BLOOD

Hereditary thrombocythemia caused by a thrombopoietin (THPO) gain-of-function mutation associated with multiple myeloma and congenital limb defects

(2012) Clemens Stockklausner et al.   ANNALS OF HEMATOLOGY

Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling

(2012) J. A. Pulikkan et al.   BLOOD

Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder

(2012) Alan S. Gamis et al.   BRITISH JOURNAL OF HAEMATOLOGY

Thrombopoietin and hematopoietic stem cells

(2011) Carolyn A. de Graaf et al.   CELL CYCLE

Transient Leukemia in Newborns Without Down Syndrome

(2011) Brent A. Williams et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Hereditary thrombocytosis not as innocent as thought? Development into acute leukemia and myelofibrosis

(2010) H. L. A. Posthuma et al.   BLOOD

Hereditary thrombocytosis caused by MPLSer505Asn is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis

(2009) L. Teofili et al.   HAEMATOLOGICA

Gene Therapy of Mpl Deficiency: Challenging Balance Between Leukemia and Pancytopenia

(2009) Daniel C Wicke et al.   MOLECULAR THERAPY