Article
Immunology
Manuela Hauser, Jean-Bertin B. Kabuya, Molly Mantus, Luc K. Kamavu, James L. Sichivula, Wycliffe M. Matende, Nora Fritschi, Timothy Shields, Frank Curriero, Anton Kvit, Gershom Chongwe, William J. Moss, Nicole Ritz, Matthew M. Ippolito
Summary: This study examined the clinical features of malaria in refugee children in high-transmission areas of Africa. The findings showed that refugee children had higher malaria prevalence and mortality rates, partly due to delayed presentation and malnutrition. Interventions tailored to the refugee context, including rapid diagnosis and referral, are necessary to reduce malaria mortality.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Environmental Sciences
Katie M. Fellows, Shar Samy, Yoni Rodriguez, Stephen G. Whittaker
Summary: Afghan refugee children resettled in Washington State have high blood lead levels, possibly due to the use of aluminum cookpots brought from Afghanistan. Furthermore, imported aluminum cookpots can also be a source of lead poisoning for residents in the United States.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Article
Environmental Sciences
Yang Liu, Chengdong Xu, Feiyan Liu, Gexin Xiao, Shaoqi Zhou, Liming Huang, Ni Lin, Jianyi Li, Dong Chen, Qi Fu, Huijun Wang, Qingfeng Du
Summary: The study revealed that the development of the lead industry is associated with children's blood lead levels in different regions of China. Economic development in leaded areas was linked to inequity in children's BLLs, while in areas without lead industries, there was little correlation between economic development and children's BLLs.
ENVIRONMENTAL POLLUTION
(2022)
Article
Public, Environmental & Occupational Health
Christian Hoover, Aaron J. Specht, David Hemenway
Summary: Between 2011 and 2019, suicide was the second leading cause of injury death in the US, with about half of all suicides involving firearms. The connection between firearms and suicide often overlooks the factor of lead exposure. This study conducted in Massachusetts found that towns with higher levels of firearm licensure had higher rates of firearm suicides and lead exposure, highlighting the relationship between lead exposure, firearms, and suicide.
PREVENTIVE MEDICINE
(2023)
Review
Public, Environmental & Occupational Health
Binh Phung
Summary: This review examines the physical health needs of resettled refugee children in the United States and formulates evidence-based guidelines and public health perspectives to ensure equitable access to healthcare for these children. It emphasizes the importance of cross-border collaboration and prioritizing the physical health of refugee children.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Yuebin Lyu, Jing Chen, Zheng Li, Liang Ding, Feng Zhao, Yingli Qu, Xulin Zheng, Zheng Zhang, Xiaojian Hu, Saisai Ji, Yifu Lu, Yawei Li, Yuanduo Zhu, Yanwei Yang, Yidan Qiu, Haocan Song, Wenli Zhang, Bing Wu, Jiayi Cai, Miao Zhang, Fangyu Li, Ying Zhu, Zhaojin Cao, John Ji, Xiaoyuan Yao, Yuxin Zheng, Xiaoming Shi
Summary: Environmental and occupational lead exposure in China has generally declined in the past two decades. However, there has been no large-scale monitoring of blood lead levels (BLLs) in the Chinese general population. This nationally representative study showed significant declines in BLLs for all age groups, particularly in children aged 3-5 years. As a result, there is a need to review and update the guidelines for screening elevated BLLs in high-risk children.
Review
Environmental Sciences
Jintao Huang, Zhijun Zeng, Xijin Xu, Qianwen Tian, Keyang Zheng, Xia Huo
Summary: Blood lead levels (BLLs) in e-waste-exposed children have been decreasing over time. A meta-analysis of 51 studies from six countries found that the total geometric mean BLL was 7.54 μg/dL. BLLs displayed a decreasing trend from 11.77 μg/dL in 2004-2006 to 4.63 μg/dL in 2016-2018. Nearly 95% of studies showed that e-waste-exposed children had significantly higher BLLs than the reference groups. The difference in BLLs between the exposure group and reference group decreased from 6.60 μg/dL in 2004 to 1.99 μg/dL in 2018. It was found that children from Guiyu had higher BLLs compared to other regions.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Christian Hoover, Gabrielle Groth Hoover, Aaron J. Specht
Summary: The study explored the association between firearm-related lead exposure and elevated blood lead levels in children aged 0-4 in Massachusetts. Results showed that sub-counties with higher rates of firearm licensure had higher rates of lead exposure among children, indicating a need for further research on the risks associated with firearm use, ownership, and lead exposure.
ENVIRONMENTAL RESEARCH
(2021)
Review
Environmental Sciences
Jintao Huang, Zhijun Zeng, Xijin Xu, Qianwen Tian, Keyang Zheng, Xia Huo
Summary: Blood lead levels (BLLs) among children in e-waste recycling areas have been decreasing over time, but are still higher compared to children not exposed to e-waste. The difference in BLLs between exposed and reference groups is gradually decreasing.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Shuo Wang, Yuan Jin, Jing Chen, Lin Lu, Yanan Li, Qianwen Zhao, Shuhua Bu, Xue Geng, Ge Guan, Weidong Qu, Yuxin Zheng, Jinglong Tang
Summary: The study investigated blood lead levels of over a million Chinese children and teenagers over the past 30 years, showing a declining trend with higher levels in boys compared to girls. Regions like Yunnan, Guizhou, and Shanxi had relatively high levels of lead exposure. Despite the decrease, Chinese children's lead levels are still higher than those in developed countries, indicating the need for more efforts in lead control for children.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Cleo Tebby, Julien Caudeville, Yasmil Fernandez, Celine Brochot
Summary: The decrease in lead levels in air and drinking water has resulted in a decrease in blood lead levels in children over the last 40 years, but there is still no known safe level of lead exposure for developmental effects. A study in France mapped predicted blood lead levels in children, finding that drinking water and food were the main sources of lead exposure, with the former being prominent in children over 2 years old. The study also showed discrepancies in predicted blood lead levels for infants and children aged 2 to 6, with the latter being more accurately predicted.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Christian Hoover, Aisha S. Dickerson, Aaron J. Specht, Gabrielle Groth Hoover
Summary: The US has the highest number of firearms in the world and primarily uses lead ammunition. This study found that firearm-related lead exposure contributes significantly to elevated blood lead levels in children. The authors recommend further research and prevention efforts to address this potential health risk.
ENVIRONMENTAL RESEARCH
(2023)
Article
Pediatrics
Joseph M. Braun, Kimberly Yolton, Nicholas Newman, David E. Jacobs, Mark Taylor, Bruce P. Lanphear
Summary: The study found that the EPA's residential dust lead regulations place children at increased risk of lead poisoning, with the 2019 post-abatement lead clearance standards associated with higher risk compared to dust lead hazard standards. Extrapolating the findings to US children, it was estimated that the 2019 EPA standards could put up to 36,700 children at risk of lead poisoning.
PEDIATRIC RESEARCH
(2021)
Article
Environmental Sciences
Given Moonga, Moses N. Chisola, Ursula Berger, Dennis Nowak, John Yabe, Hokuto Nakata, Shouta Nakayama, Mayumi Ishizuka, Stephan Bose-O'Reilly
Summary: This study used a geospatial approach to investigate spatial clustering and hotspots of blood lead levels in children in Kabwe, Zambia. The results showed distinct hotspots with high lead levels in communities close to the old lead and zinc mining site, and coldspots with low lead levels in areas distant to the mine.
ENVIRONMENTAL RESEARCH
(2022)
Article
Pediatrics
Xiao-Jun Cheng, Guang-Bo Li, Shuang-Shuang Zhang, Ying Liu, Yi-Chen Dong, Xue-Ning-Li
Summary: This study investigated the factors that affect blood lead levels (BLLs) in children in Shenyang and found that BLLs in children in Shenyang are still higher than in developed countries. Consumption of puffed grains and eggs is associated with higher BLLs, while often hand washing before meals may be protective against high BLLs.
Article
Environmental Sciences
Andrea Cediel Ulloa, Anda Gliga, Tanzy M. Love, Daniela Pineda, Daniel W. Mruzek, Gene E. Watson, Philip W. Davidson, Conrad F. Shamlaye, J. J. Strain, Gary J. Myers, Edwin van Wijngaarden, Joelle Ruegg, Karin Broberg
Summary: The study assessed the association between prenatal MeHg exposure and DNA methylation of nervous system-related genes in children, finding higher prenatal MeHg exposure to be associated with increased DNA methylation at specific CpG sites.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Marianne Lian, Cara L. Field, Edwin van Wijngaarden, Carlos Rios, J. Margaret Castellini, Denise J. Greig, Lorrie D. Rea, Denver J. Coleman, Christine E. Thomson, Frances M. D. Gulland, Todd M. O'Hara
Summary: The study found important associations between low-level exposure to monomethyl mercury and behavior as well as rehabilitation time in harbor seal pups. Specifically, a significant negative correlation was found between total Hg concentration and responses to tactile stimulation and movements during both the intensive care unit (ICU) stage and pool stage of rehabilitation. Additionally, a significant sex difference was observed, with female pups showing higher total Hg concentrations compared to male pups.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Nursing
Hayley Martin, Edwin van Wijngaarden, Christopher L. Seplaki, Jenney Stringer, Geoffrey C. Williams, Ann M. Dozier
Summary: The study validated a breastfeeding-specific adaptation of the TSRQ, using it to predict prenatal breastfeeding intentions and outcomes, which may help identify patients at risk for suboptimal breastfeeding outcomes before delivery.
JOURNAL OF HUMAN LACTATION
(2022)
Review
Endocrinology & Metabolism
Anna M. Monaghan, Maria S. Mulhern, Emeir M. McSorley, J. J. Strain, Matthew Dyer, Edwin van Wijngaarden, Alison J. Yeates
Summary: The systematic review found that mild to moderate iodine deficiency during pregnancy is associated with adverse neurodevelopmental outcomes in offspring. Studies incorporating assessment of urinary iodine and dietary intake of iodine rich foods showed a negative association with child cognitive outcomes. Milk was identified as the main dietary source of iodine, and it is suggested that dietary intake data may indicate a stronger association with cognitive outcomes than urinary iodine measurements alone. Further research is needed to explore the relationship between urinary iodine assessments and dietary intakes in assessing iodine deficiency during pregnancy.
Article
Oncology
Elizabeth K. Belcher, Eva Culakova, Nikesha J. Gilmore, Sara J. Hardy, Amber S. Kleckner, Ian R. Kleckner, Lianlian Lei, Charles Heckler, Michael B. Sohn, Bryan D. Thompson, Louis T. Lotta, Zachary A. Werner, Jodi Geer, Judith O. Hopkins, Steven W. Corso, David Q. Rich, Edwin van Wijngaarden, Michelle C. Janelsins
Summary: Inflammation levels are elevated in breast cancer patients during chemotherapy, which is associated with worse attention and processing speed. Lower levels of anti-inflammatory cytokines and higher levels of inflammatory cytokines and receptors are observed in patients. Further confirmatory studies are needed.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Article
Clinical Neurology
Jennifer Vermilion, Erika F. Augustine, Heather R. Adams, Amy Vierhile, Alyssa T. Collins, Michael P. McDermott, Thomas G. O'Connor, Roger Kurlan, Edwin van Wijngaarden, Jonathan W. Mink
Summary: The study found no significant differences in risky behaviors between youth with TS and control youth, but ADHD was more common in youth with TS, and those who were bullied in school had higher ADHD symptom severity scores.
PEDIATRIC NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Alexis Zavez, Sally W. Thurston, Matthew D. Rand, Daniel W. Mruzek, Tanzy Love, Tristram Smith, Conrad F. Shamlaye, Edwin van Wijngaarden
Summary: This prospective cohort study in the Republic of Seychelles found that cesarean delivery was not associated with adverse effects on child neurodevelopment at 20 months or 7 years. Children born via cesarean delivery had slightly higher scores on a test measuring infant temperament at 20 months, but delivery mode was not linked to any developmental outcomes at 7 years.
MATERNAL AND CHILD HEALTH JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
H. Alzamil, T. T. Wu, E. van Wijngaarden, M. Mendoza, H. Malmstrom, K. Fiscella, D. T. Kopycka-Kedzierawski, R. J. Billings, J. Xiao
Summary: This study found that wearing removable dentures is a risk predictor for increased pneumonia incidence among older adults, even after adjusting for other risk factors. Clinicians and older patients can refer to these study results when choosing dental prostheses to restore missing teeth.
JDR CLINICAL & TRANSLATIONAL RESEARCH
(2023)
Article
Environmental Sciences
Toni Spence, Alexis Zavez, Philip J. Allsopp, Marie C. Conway, Alison J. Yeates, Maria S. Mulhern, Edwin van Wijngaarden, J. J. Strain, Gary J. Myers, Gene E. Watson, Philip W. Davidson, Conrad F. Shamlaye, Sally W. Thurston, Emeir M. McSorley
Summary: The study found that methylmercury exposure from fish consumption does not seem to affect inflammation markers in cord blood. The association of cord n-3 PUFA with lower IL-10 and total Th2 cytokines suggests that they may have a beneficial influence on the regulation of the inflammatory milieu. These findings are important for public health advice and warrant further investigation in follow-up studies.
ENVIRONMENTAL RESEARCH
(2022)
Article
Neurosciences
Sally W. Thurston, Gary Myers, Daniel Mruzek, Donald Harrington, Heather Adams, Conrad Shamlaye, Edwin van Wijngaarden
Summary: The study found that postnatal MeHg exposure may be adversely associated with neurodevelopmental outcomes in early adulthood, but the results need confirmation in other cohorts.
Article
Neurosciences
Karin Wahlberg, Daniela Pineda, Grazyna Zareba, Sally W. Thurston, Philip W. Davidson, Conrad F. Shamlaye, Gary J. Myers, Matthew Rand, Edwin Van Wijngaarden, Karin Broberg
Summary: This study suggests that genetic variation in ABC transporter genes in children may contribute to prenatal methylmercury exposure and early neurodevelopment. One specific gene, ABCC1 rs11075290, was associated with cord blood MeHg concentrations, while another gene, ABCB1 rs10276499, showed an interaction effect on the relationship between cord MeHg and the Mental Developmental Index of the Bayley Scales of Infant Development.
Article
Biochemistry & Molecular Biology
Juho Joutsa, Khaled Moussawi, Shan H. Siddiqi, Amir Abdolahi, William Drew, Alexander L. Cohen, Thomas J. Ross, Harshawardhan U. Deshpande, Henry Z. Wang, Joel Bruss, Elliot A. Stein, Nora D. Volkow, Jordan H. Grafman, Edwin van Wijngaarden, Aaron D. Boes, Michael D. Fox
Summary: Drug addiction is a significant public health crisis, and new treatments are urgently needed. Research has shown that focal brain damage can lead to addiction remission, which can be used to identify potential therapeutic targets. The study analyzed cohorts of smokers with addiction and found that specific patterns of brain connectivity were associated with addiction remission. These findings were reproducible across different cohorts and specific to addiction metrics.
Biographical-Item
Neurosciences
Gary J. Myers, Edwin van Wijngaarden
Article
Oncology
Amber S. Kleckner, Edwin van Wijngaarden, Todd A. Jusko, Ian R. Kleckner, Po -Ju Lin, Karen M. Mustian, Luke J. Peppone
Summary: A higher diet quality, as indicated by higher serum concentrations of carotenoids, vitamin A, and vitamin E, is associated with lower cancer-related fatigue. However, this association is not observed among cancer survivors. This study highlights the importance of diet and nutrition interventions in addressing cancer-related fatigue, particularly in post-treatment survivorship.
CANCER RESEARCH COMMUNICATIONS
(2022)
Article
Psychology, Developmental
Jennifer Vermilion, Carolina Pedraza, Erika F. Augustine, Heather R. Adams, Amy Vierhile, Adam B. Lewin, Alyssa T. Collins, Michael P. McDermott, Thomas O'Connor, Roger Kurlan, Edwin van Wijngaarden, Tanya K. Murphy, Jonathan W. Mink
Summary: The study found that anxiety symptoms differed between youth with and without tic disorders, with separation anxiety and physical symptom scores being higher in the former group. This has important implications for targeting anxiety treatment in youth with tic disorders.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2021)
