Ventilator-induced diaphragm dysfunction: cause and effect

Phrenic nerve stimulation protects against mechanical ventilation-induced diaphragm dysfunction in rats

(2013) Meirong Yang et al.   MUSCLE & NERVE

Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation

(2012) Martin Picard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction

(2012) Segolene Mrozek et al.   ANESTHESIOLOGY

Toll-like Receptor 4 Signaling in Ventilator-induced Diaphragm Atrophy

(2012) Willem-Jan M. Schellekens et al.   ANESTHESIOLOGY

Diaphragm Muscle Thinning in Patients Who Are Mechanically Ventilated

(2012) Horiana B. Grosu et al.   CHEST

Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction*

(2012) Anouk Agten et al.   CRITICAL CARE MEDICINE

Cross-talk between the calpain and caspase-3 proteolytic systems in the diaphragm during prolonged mechanical ventilation

(2012) W. Bradley Nelson et al.   CRITICAL CARE MEDICINE

Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy

(2012) Matthew B. Hudson et al.   CRITICAL CARE MEDICINE

Oxidative stress and disuse muscle atrophy

(2012) Scott K. Powers et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Titin and diaphragm dysfunction in mechanically ventilated rats

(2012) Hieronymus W. H. van Hees et al.   INTENSIVE CARE MEDICINE

Role of p70S6K1-mediated Phosphorylation of eIF4B and PDCD4 Proteins in the Regulation of Protein Synthesis

(2012) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Muscle Protein Synthetic Responses to Exercise: Effects of Age, Volume, and Intensity

(2012) V. Kumar et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation

(2012) Huibin Tang et al.   MUSCLE & NERVE

Weaning Patients from the Ventilator

(2012) John F. McConville et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extubation process in bed-ridden elderly intensive care patients receiving inspiratory muscle training: a randomized clinical trial

(2012) Samária Samária Ali Cader et al.   Clinical Interventions in Aging

Angiotensin II, Oxidative Stress and Skeletal Muscle Wasting

(2011) Sergiy Sukhanov et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Mechanistic Links Between Oxidative Stress and Disuse Muscle Atrophy

(2011) Scott K. Powers et al.   ANTIOXIDANTS & REDOX SIGNALING

N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation*

(2011) Anouk Agten et al.   CRITICAL CARE MEDICINE

Diaphragm dysfunction assessed by ultrasonography: Influence on weaning from mechanical ventilation*

(2011) Won Young Kim et al.   CRITICAL CARE MEDICINE

Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness*

(2011) Scott K. Powers et al.   CRITICAL CARE MEDICINE

Nuclear factor-κB signaling contributes to mechanical ventilation-induced diaphragm weakness*

(2011) Ashley J. Smuder et al.   CRITICAL CARE MEDICINE

Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis

(2011) Huibin Tang et al.   FASEB JOURNAL

Endurance exercise attenuates ventilator-induced diaphragm dysfunction

(2011) Ashley J. Smuder et al.   JOURNAL OF APPLIED PHYSIOLOGY

Redox homeostasis, oxidative stress and disuse muscle atrophy

(2011) Maria Antonietta Pellegrino et al.   JOURNAL OF PHYSIOLOGY-LONDON

Beyond atrophy: redox mechanisms of muscle dysfunction in chronic inflammatory disease

(2011) Michael B. Reid et al.   JOURNAL OF PHYSIOLOGY-LONDON

Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men

(2011) Nicholas A. Burd et al.   JOURNAL OF PHYSIOLOGY-LONDON

Diaphragm Muscle Weakness in an Experimental Porcine Intensive Care Unit Model

(2011) Julien Ochala et al.   PLoS One

When Should Sedation or Neuromuscular Blockade Be Used During Mechanical Ventilation?

(2011) S. Bennett et al.   Respiratory Care

Inspiratory muscle training improves maximal inspiratory pressure and may assist weaning in older intubated patients: a randomised trial

(2011) Samária Ali Cader et al.   Journal of Physiotherapy

Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy

(2010) Sabah N. A. Hussain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Proteolysis, Myosin Depletion, and Atrophic AKT-FOXO Signaling in Human Diaphragm Disuse

(2010) Sanford Levine et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans

(2010) Samir Jaber et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet

(2010) Boris Jung et al.   ANESTHESIOLOGY

Mechanical Ventilation-Induced Oxidative Stress in the Diaphragm

(2010) Darin J. Falk et al.   CHEST

Prolonged mechanical ventilation alters diaphragmatic structure and function

(2010) Scott K. Powers et al.   CRITICAL CARE MEDICINE

Oxidation enhances myofibrillar protein degradation via calpain and caspase-3

(2010) Ashley J. Smuder et al.   FREE RADICAL BIOLOGY AND MEDICINE

Functions and regulation of the 70kDa ribosomal S6 kinases

(2010) Tim R. Fenton et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Oxidative stress is required for mechanical ventilation-induced protease activation in the diaphragm

(2010) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Interactive effects of corticosteroid and mechanical ventilation on diaphragm muscle function

(2010) Catherine S.H. Sassoon et al.   MUSCLE & NERVE

Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation

(2009) Joseph M. McClung et al.   CRITICAL CARE MEDICINE

Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production

(2009) Andreas N. Kavazis et al.   FREE RADICAL BIOLOGY AND MEDICINE

EMD 57033 partially reverses ventilator-induced diaphragm muscle fibre calcium desensitisation

(2009) Julien Ochala et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Redox regulation of diaphragm proteolysis during mechanical ventilation

(2008) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effects of Acute Administration of Corticosteroids during Mechanical Ventilation on Rat Diaphragm

(2008) Karen Maes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction

(2008) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Acute effects of high-dose methylprednisolone on diaphragm muscle function

(2008) Catherine S. H. Sassoon et al.   MUSCLE & NERVE

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

(2008) Sanford Levine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production

(2008) Scott K. Powers et al.   PHYSIOLOGICAL REVIEWS