Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12

An Official American Thoracic Society Research Statement: Noninfectious Lung Injury after Hematopoietic Stem Cell Transplantation: Idiopathic Pneumonia Syndrome

(2011) Angela Panoskaltsis-Mortari et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macrophage metalloelastase (MMP-12) as a target for inflammatory respiratory diseases

(2009) Vincent Lagente et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Transforming growth factor β as a therapeutic target in systemic sclerosis

(2009) John Varga et al.   Nature Reviews Rheumatology

Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx

(2008) R. A. Dean et al.   BLOOD

The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke

(2008) C Le Quément et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

(2007) Khalid Puthawala et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

(2007) Gerald S. Horan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE