Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats

Rho-kinase: important new therapeutic target in cardiovascular diseases

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Disruption of Na + ,HCO 3 − Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca 2+ Sensitivity, and Hypertension Development in Mice

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Effect of carbon dioxide inhalation on pulmonary hypertension induced by increased blood flow and hypoxia

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Outcome of Pediatric Patients With Pulmonary Arterial Hypertension in the Era of New Medical Therapies

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Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat

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Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension

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Hypercapnic Acidosis Reduces Oxidative Reactions in Endotoxin-induced Lung Injury

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The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase

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Pulmonary vascular and cardiac effects of peroxynitrite decomposition in newborn rats

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Peroxynitrite mediates right-ventricular dysfunction in nitric oxide-exposed juvenile rats

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Effect of Carbon Dioxide on Pulmonary Vascular Tone at Various Pulmonary Arterial Pressure Levels Induced by Endothelin-1

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Effects of Rho-Kinase Inhibition on Pulmonary Hypertension, Lung Growth, and Structure in Neonatal Rats Chronically Exposed to Hypoxia

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Chronic hypercapnia downregulates arginase expression and activity and increases pulmonary arterial smooth muscle relaxation in the newborn rat

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Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats

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Effects of Fixed-Dose Isosorbide Dinitrate/Hydralazine on Diastolic Function and Exercise Capacity in Hypertension-Induced Diastolic Heart Failure

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Hypercapnia and the neonate

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Preservation of cGMP-induced relaxation of pulmonary veins of fetal lambs exposed to chronic high altitude hypoxia: role of PKG and Rho kinase

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Molecular pathogenesis of pulmonary arterial hypertension

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PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation

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Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide

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Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats

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