Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration

Physiology and Pharmacology of the Enteroendocrine Hormone Glucagon-Like Peptide-2

(2013) Daniel J. Drucker et al.   Annual Review of Physiology

Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons

(2013) Xuemei Shi et al.   Cell Metabolism

Glucagon-like peptide 2 induces vasoactive intestinal polypeptide expression in enteric neurons via phophatidylinositol 3-kinase-γ signaling

(2012) Elaine de Heuvel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer

(2012) Shivangi Trivedi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

GLP-2 receptors in human disease: High expression in gastrointestinal stromal tumors and Crohn’s disease

(2012) Meike Körner et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The “cryptic” mechanism of action of glucagon-like peptide-2

(2011) Katherine J. Rowland et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome

(2011) P. B. Jeppesen et al.   GUT

Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

(2010) C.C. Taylor-Edwards et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Mechanism of Action of Glucagon-Like Peptide-2 to Increase IGF-I mRNA in Intestinal Subepithelial Fibroblasts

(2010) Jason L. S. Leen et al.   ENDOCRINOLOGY

GLP-2 Receptor Agonism Ameliorates Inflammation and Gastrointestinal Stasis in Murine Postoperative Ileus

(2010) B. A. Moore et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The effects of glucagon-like peptide 2 on enteric neurons in intestinal inflammation

(2010) D. L. Sigalet et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Early but not late administration of glucagon-like peptide-2 following ileo-cecal resection augments putative intestinal stem cell expansion

(2009) Aaron P. Garrison et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Four-month treatment with GLP-2 significantly increases hip BMD

(2009) Dennis B. Henriksen et al.   BONE

Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohnʼs disease

(2009) Alan L. Buchman et al.   INFLAMMATORY BOWEL DISEASES

Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats

(2008) David W. Nelson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats

(2008) Xiaowen Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inhibiting dipeptidyl peptidase activity partially ameliorates colitis in mice

(2008) Roger Yazbeck   Frontiers in Bioscience-Landmark

A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

(2008) Claudia Mitchell et al.   Nature Protocols

Glucagon-Like Peptide-2 Activates β-Catenin Signaling in the Mouse Intestinal Crypt: Role of Insulin-Like Growth Factor-I

(2007) Philip E. Dubé et al.   ENDOCRINOLOGY

Porcine glucagon-like peptide-2: Structure, signaling, metabolism and effects

(2007) Nis B. Pedersen et al.   REGULATORY PEPTIDES