Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

(2012) Young-Ah Moon et al.   Cell Metabolism

Liver-Specific Expression of Transcriptionally Active SREBP-1c Is Associated with Fatty Liver and Increased Visceral Fat Mass

(2012) Birgit Knebel et al.   PLoS One

Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance

(2012) Lu-Ping Ren et al.   PLoS One

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Non-alcoholic fatty liver disease

(2011) Briohny W. Smith et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Current therapeutic strategies in non-alcoholic fatty liver disease

(2011) J. K. Dowman et al.   DIABETES OBESITY & METABOLISM

Non-alcoholic fatty liver disease (NAFLD): why you should care, when you should worry, what you should do

(2011) Edward Lebovics et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

(2011) Kezhong Zhang et al.   EMBO JOURNAL

Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice

(2011) Jiansheng Huang et al.   FASEB JOURNAL

Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice

(2011) Michael J. Jurczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor-α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis

(2011) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review

(2011) Christian Thoma et al.   JOURNAL OF HEPATOLOGY

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor   in Mouse Liver Reveals Extensive Sharing of Binding Sites

(2011) M. Boergesen et al.   MOLECULAR AND CELLULAR BIOLOGY

Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment

(2011) Briohny W. Smith et al.   Nature Reviews Endocrinology

Nonalcoholic Fatty Liver Disease

(2011) Krzysztof Lukasz Kopec et al.   NUTRITION IN CLINICAL PRACTICE

Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression

(2011) Yun-Seung Jeong et al.   PLoS One

The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis

(2011) Lisa B. Van Wagner et al.   Therapeutic Advances in Gastroenterology

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice

(2010) Myoung-Su Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic control ofde novolipogenesis: role in diet-induced obesity

(2010) Maggie S. Strable et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fatty acid regulation of hepatic lipid metabolism

(2010) Donald B Jump   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Recent insights into fatty liver, metabolic dyslipidaemia and their links to insulin resistance

(2010) David B Savage et al.   CURRENT OPINION IN LIPIDOLOGY

Palmitoylation of ketogenic enzyme HMGCS2 enhances its interaction with PPARα and transcription at the Hmgcs2 PPRE

(2010) Morris A. Kostiuk et al.   FASEB JOURNAL

Non-alcoholic fatty liver disease: the hepatic consequence of obesity and the metabolic syndrome

(2010) J. Bernadette Moore   PROCEEDINGS OF THE NUTRITION SOCIETY

Peroxisome Proliferator-Activated Receptor Alpha Target Genes

(2010) Maryam Rakhshandehroo et al.   PPAR Research

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives

(2009) B. Viollet et al.   Acta Physiologica

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome

(2009) C. H. KIM et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones

(2009) Seong Hwan Hwahng et al.   HEPATOLOGY

Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice

(2009) Maaike H. Oosterveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

Recent advances in nonalcholic fatty liver disease

(2008) Victoria Greenfield et al.   CURRENT OPINION IN GASTROENTEROLOGY

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Causes and Metabolic Consequences of Fatty Liver

(2008) Norbert Stefan et al.   ENDOCRINE REVIEWS

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE

Current and Emerging Therapies in Nonalcoholic Fatty Liver Disease

(2008) Maryam Kashi et al.   SEMINARS IN LIVER DISEASE

Fatty Liver

(2007) Anna Kotronen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY