TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival

The cytoplasmic domains of TNFα-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding

(2010) David J. Killock et al.   BIOCHEMICAL JOURNAL

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

(2010) Athena Chalaris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ErbB4 promotes cyclooxygenase-2 expression and cell survival in colon epithelial cells

(2010) Mark R Frey et al.   LABORATORY INVESTIGATION

Direct Activation of TACE-Mediated Ectodomain Shedding by p38 MAP Kinase Regulates EGF Receptor-Dependent Cell Proliferation

(2010) Pinglong Xu et al.   MOLECULAR CELL

Intestinal inflammation is coordinated by the metalloprotease ADAM17

(2009) Stefan Rose-John et al.   CYTOKINE

Epidermal Growth Factor Receptor Activation Protects Gastric Epithelial Cells From Helicobacter pylori-Induced Apoptosis

(2009) Fang Yan et al.   GASTROENTEROLOGY

Tumor Necrosis Factor-α–Converting Enzyme Is a Key Regulator of Agonist-Induced Cardiac Hypertrophy and Fibrosis

(2009) Xiang Wang et al.   HYPERTENSION

Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways

(2009) Sandra E. Ghayad et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

(2009) Daekee Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical utility of type 1 growth factor receptor expression in colon cancer

(2008) Sher-Ping Leung et al.   AMERICAN JOURNAL OF SURGERY

System-wide Investigation of ErbB4 Reveals 19 Sites of Tyr Phosphorylation that Are Unusually Selective in Their Recruitment Properties

(2008) Alexis Kaushansky et al.   CHEMISTRY & BIOLOGY

The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF

(2008) Mark R. Frey et al.   GASTROENTEROLOGY

Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis

(2008) T. Yamaoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA