Article
Gastroenterology & Hepatology
Yervant Ichkhanian, Mohammad A. Al-Haddad, Chelsea C. Jacobs, Alexander Schlachterman, Juliana Yang, Andrew Canakis, Raymond Kim, Arcelia Guerson-Gil, Lionel S. D'Souza, Eva Alsheik, Brian D. Ginnebaugh, Mouen A. Khashab, Tobias Zuchelli, Kellie McFarlin, Cyrus Piraka
Summary: In patients with refractory symptoms after GNS, G-POEM can be a reasonable salvage therapy to provide further symptomatic relief, with evidence of a potential additive effect of both G-POEM and GNS.
GASTROINTESTINAL ENDOSCOPY
(2023)
Review
Chemistry, Physical
Johann Shane Tian, Andy Tay
Summary: With the persisting complexity of chronic diseases, there is a growing need to develop cell therapies as a solution. However, the shortage of starter cells and the time-consuming manufacturing process hinder accessibility to patients. This review discusses the importance of maximizing cell yield during manufacturing and explores strategies for modulating cell proliferation, specifically through electrical stimulation. Bridging the gap between academic investigation and industrial application is crucial for advancing cell therapy production.
Article
Gastroenterology & Hepatology
Guillaume Gourcerol, Benoit Coffin, Bruno Bonaz, Helene Hanaire, Stanislas Bruley Des Varannes, Frank Zerbib, Robert Caiazzo, Jean Charles Grimaud, Francois Mion, Samy Hadjadj, Paul Valensi, Lucine Vuitton, Guillaume Charpentier, Alain Ropert, Romain Altwegg, Philippe Pouderoux, Etienne Dorval, Michel Dapoigny, Henri Duboc, Pierre Yves Benhamou, Aurelie Schmidt, Nathalie Donnadieu, Philippe Ducrotte, Bruno Guerci
Summary: The study aimed to evaluate the efficacy, safety, and medico-economic impact of Enterra therapy for chronic medically refractory nausea and vomiting. The results showed that Enterra therapy significantly improved the gastrointestinal quality of life index score and reduced vomiting frequency. It also decreased healthcare costs and resulted in savings for the patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Multidisciplinary Sciences
Zachary P. Rosenthal, Ryan Raut, Ryan M. Bowen, Abraham Z. Snyder, Joseph P. Culver, Marcus E. Raichle, Jin-Moo Lee
Summary: Slow waves, crucial for neural plasticity and memory, were found to be globally propagating low-frequency oscillations during sleep and anesthesia. Experimental results showed that somatosensory stimulation can evoke bilateral waves and under anesthesia, rhythmic stimuli can elicit globally resonant, front-to-back propagating slow waves.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Engineering, Biomedical
Gongkai Ye, Pirashanth Theventhiran, Kei Masani
Summary: This study investigated the fatigue reducing ability of spatially distributed sequential stimulation (SDSS) in functional electrical stimulation (FES)-rowing. The results showed that SDSS significantly reduced fatigue and lengthened the rowing time by approximately 30%. The study demonstrated that the application of SDSS could enhance the effectiveness of FES-rowing as a rehabilitative exercise.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2022)
Review
Neurosciences
Leo K. Cheng, Nipuni D. Nagahawatte, Recep Avci, Peng Du, Zhongming Liu, Niranchan Paskaranandavadivel
Summary: This review discusses the use of gastric pacing and stimulation strategies in treating motility disorders, as well as targeting nerves in the stomach to modulate stomach function. The article summarizes effective parameters and limitations in existing studies, and explores the use of mathematical models to refine pacing and stimulation protocols. Additionally, future directions and challenges in this field are also discussed.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
M. G. Peng, E. Iseri, A. Simonyan, P. Lam, T. Kim, S. Medvidovic, J. Paknahad, M. Machnoor, G. Lazzi, K. K. Gokoffski
Summary: Failure to direct axon regeneration to appropriate targets is a major barrier to restoring function after nerve injury. We demonstrate that a new class of asymmetric, charge balanced (ACB) waveforms are effective at directing retinal ganglion cell axon growth, in vitro, without compromising cell viability. This work can serve as a practical guideline for the potential deployment of electrical stimulation as a treatment strategy for nerve injury.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yoshiki Kaneoke, Tomohiro Donishi, Masaki Terada
Summary: The study demonstrates that parasagittal gastric cine MRI can measure gastric oscillatory contractions around 0.05 Hz and is correlated with EGG recordings, making it a valuable tool for detecting and quantifying gastric motility abnormalities.
MAGNETIC RESONANCE IMAGING
(2021)
Review
Chemistry, Multidisciplinary
Giorgio Conta, Alberto Libanori, Trinny Tat, Guorui Chen, Jun Chen
Summary: Current research focuses on developing self-powered IOB therapeutic devices using TENG technology, known for its bioconformability, low cost, simple manufacturability, and self-power capabilities. TENG-induced ES holds promise for novel therapeutic interventions and could pave the way for the development of personalized healthcare systems.
ADVANCED MATERIALS
(2021)
Article
Surgery
Doris Kim, Ryan Gedney, Shelby Allen, Haley Zlomke, Elizabeth Winter, John Craver, A. D. Pinnola, Will Lancaster, David Adams
Summary: This study retrospectively reviewed patients who underwent gastric electrical stimulation (GES) over a 10-year period and found that patients with gastroparesis had different clinical outcomes after GES therapy based on underlying etiology. Diabetic patients were more likely to continue therapy, while idiopathic patients were more likely to have the device removed.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Medicine, General & Internal
Mahmoud M. M. Dboba, Nor Azlin Mohd Nordin, Haidzir Manaf, Hanif Farhan Mohd Rasdi
Summary: This study aims to summarize the evidence on the effects of neuromuscular electrical stimulation combined with constraint-induced movement therapy in stroke patients. Various databases were used for literature review, and the study will include independent article selection, data extraction, and quality evaluation. The results will provide therapists with the available evidence to choose the best treatment for upper extremity dysfunction in stroke patients.
Article
Neurosciences
Matija Milosevic, Tomoya Nakanishi, Atsushi Sasaki, Akiko Yamaguchi, Taishin Nomura, Milos R. Popovic, Kimitaka Nakazawa
Summary: The study demonstrated that FEST can effectively improve motor function and increase cortical activations in individuals with chronic TBI. Short-term and long-term assessments indicated increased M1 activation after FEST intervention, which remained stable during follow-ups, suggesting a promising rehabilitation approach for TBI patients.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Charmaine Diep, Gary Garcia-Molina, Jeff Jasko, Jessica Manousakis, Lynn Ostrowski, David White, Clare Anderson
Summary: The study shows that consecutive nights of acoustic stimulation can enhance slow wave activity, improve alertness and attention, indicating potential benefits for individuals with chronic sleep restriction.
Article
Gastroenterology & Hepatology
Heithem Soliman, Martha A. Schalla, Benoit Coffin, Guillaume Gourcerol
Summary: This study retrospectively investigated the safety of gastric electrical stimulation (GES) during pregnancy and found no serious maternal or fetal complications related to GES. Mild pain at the implantation site was reported during pregnancy, but no other severe complications occurred. The severity and frequency of nausea and vomiting increased during the first trimester and decreased after delivery.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Engineering, Biomedical
Jiayue Cao, Xiaokai Wang, Terry L. Powley, Zhongming Liu
Summary: The study found that neurons in the nucleus tractus solitarius (NTS) exhibit high selectivity to the orientation of electrical stimulation, with the strongest responses observed when the current flows in parallel with the vagal intramuscular arrays (IMAs) underlying the smooth muscle fibers. This suggests that the orientation of gastric electrical stimulation (GES) plays a critical role in engaging vagal afferents effectively, and should be considered in light of the structural phenotypes of vagal terminals in the stomach.
JOURNAL OF NEURAL ENGINEERING
(2021)