Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury

A two-pronged weapon in the fight against fibrosis. Focus on “Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury”

(2014) Rennolds S Ostrom   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of Wnt/β-Catenin Signaling Promotes Engraftment of Mesenchymal Stem Cells to Repair Lung Injury

(2013) Zhaorui Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension

(2012) Abigail S. Forrest et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Profibrotic Role of miR-154 in Pulmonary Fibrosis

(2012) Jadranka Milosevic et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

(2012) Jun Wei et al.   ARTHRITIS AND RHEUMATISM

Progress Toward Improving Animal Models for Idiopathic Pulmonary Fibrosis

(2011) Amber L. Degryse et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Secretion of rat tracheal epithelial cells induces mesenchymal stem cells to differentiate into epithelial cells

(2011) Zhaorui Sun et al.   CELL BIOLOGY INTERNATIONAL

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-β Signaling Through SMAD2 in a β-Catenin-Dependent Manner

(2011) Jon M. Carthy et al.   PLoS One

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF)

(2010) Katerina M. Antoniou et al.   RESPIRATORY MEDICINE

Mesenchymal stem cells: Molecular characteristics and clinical applications

(2010) Cristina Sancricca   World Journal of Stem Cells

Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis

(2009) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Roles of Wnt/β-catenin signaling in epithelial differentiation of mesenchymal stem cells

(2009) Yajing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Propping up a destructive regime

(2009) Randall T. Peterson   NATURE

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis

(2008) Annika Andersson-Sjöland et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY