Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle

Chronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle

(2014) Danielle R. Plomaritas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Protective effects of endothelin-A receptor antagonist BQ123 against LPS-induced oxidative stress in lungs

(2014) Aleksandra Piechota et al.   Pharmacological Reports

NFAT is required for spontaneous pulmonary hypertension in superoxide dismutase 1 knockout mice

(2013) Juan Manuel Ramiro-Diaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetically encoded fluorescent redox sensors

(2013) Konstantin A. Lukyanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Effects of Reactive Oxygen Species on NFAT Activation and Translocation in Adult Rabbit Ventricular Myocytes

(2013) Stefanie Walther et al.   BIOPHYSICAL JOURNAL

Role for DNA Damage Signaling in Pulmonary Arterial Hypertension

(2013) Jolyane Meloche et al.   CIRCULATION

Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167

(2013) Ruslan Rafikov et al.   FREE RADICAL BIOLOGY AND MEDICINE

HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging

(2012) Dmitry S. Bilan et al.   ACS Chemical Biology

Enhanced Depolarization-Induced Pulmonary Vasoconstriction Following Chronic Hypoxia Requires EGFR-Dependent Activation of NAD(P)H Oxidase 2

(2012) Charles E. Norton et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of inhibition of superoxide dismutase on motor neurons during growth: Comparison of phosphorylated and non-phosphorylated neurofilament-containing spinal neurons by histogram distribution

(2012) Risa Isonaka et al.   BRAIN RESEARCH

Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH

(2012) Audrey Courboulin et al.   EUROPEAN RESPIRATORY JOURNAL

Endothelin 1 Activation of Endothelin A Receptor/NADPH Oxidase Pathway and Diminished Antioxidants Critically Contribute to Endothelial Progenitor Cell Reduction and Dysfunction in Salt-Sensitive Hypertension

(2012) Dan-Dan Chen et al.   HYPERTENSION

Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow

(2012) Sanjiv Kumar et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

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(2012) Mohamed Ahmed et al.   MOLECULAR MEDICINE

Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries

(2011) Sergio de Frutos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice

(2011) R. Bierer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of cyclooxygenase-2 and cytosolic phospholipase A2gene expression by lipopolysaccharide through the RNA-binding protein HuR: involvement of NADPH oxidase, reactive oxygen species and mitogen-activated protein kinases

(2011) Wei-Ning Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

(2011) Roxane Paulin et al.   CIRCULATION

Role for miR-204 in human pulmonary arterial hypertension

(2011) Audrey Courboulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

(2011) Gopinath Sutendra et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Import, Maturation, and Function of SOD1 and Its Copper Chaperone CCS in the Mitochondrial Intermembrane Space

(2010) Hibiki Kawamata et al.   ANTIOXIDANTS & REDOX SIGNALING

Hypoxia Induces Intracellular Ca2+ Release by Causing Reactive Oxygen Species-Mediated Dissociation of FK506-Binding Protein 12.6 from Ryanodine Receptor 2 in Pulmonary Artery Myocytes

(2010) Bo Liao et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidant-Redox Regulation of Pulmonary Vascular Responses to Hypoxia and Nitric Oxide-cGMP Signaling

(2010) Michael S. Wolin et al.   Cardiology in Review

Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension

(2010) Stephen L. Archer et al.   CIRCULATION

ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca2+ entry

(2009) Nikki L. Jernigan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

(2009) Kathleen E. Dennis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA

(2009) Brad R. S. Broughton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ROS-Dependent Signaling Mechanisms for Hypoxic Ca2+ Responses in Pulmonary Artery Myocytes

(2009) Yong-Xiao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Prolonged Hypoxia Increases ROS Signaling and RhoA Activation in Pulmonary Artery Smooth Muscle and Endothelial Cells

(2009) Annie Y. Chi et al.   ANTIOXIDANTS & REDOX SIGNALING

Reduction of mitochondrial H2O2by overexpressing peroxiredoxin 3 improves glucose tolerance in mice

(2008) Liuji Chen et al.   AGING CELL

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia

(2008) Nikki L. Jernigan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Constriction of pulmonary artery by peroxide: role of Ca2+ release and PKC

(2008) Ghazaleh Esmaeil Pourmahram et al.   FREE RADICAL BIOLOGY AND MEDICINE

Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca2+ sensitization

(2008) Greg A. Knock et al.   FREE RADICAL BIOLOGY AND MEDICINE