Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2

Can you blame cold feet on Epac (and Rap1A)? Focus on “Cyclic AMP-Rap1A signaling activates RhoA to induce α2C-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells”

(2012) Martin C. Michel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cyclic AMP-Rap1A signaling activates RhoA to induce α2c-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells

(2012) Selvi C. Jeyaraj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mutations in the N-terminal Actin-Binding Domain of Filamin C Cause a Distal Myopathy

(2011) Rachael M. Duff et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Intracellular α2C-Adrenoceptors: Storage depot, stunted development or signaling domain?

(2011) Maqsood A. Chotani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Distal myopathy with upper limb predominance caused by filamin C haploinsufficiency

(2011) V. Guergueltcheva et al.   NEUROLOGY

A novel heterozygous deletion–insertion mutation (2695–2712 del/GTTTGT ins) in exon 18 of the filamin C gene causes filaminopathy in a large Chinese family

(2010) Xinghua Luan et al.   NEUROMUSCULAR DISORDERS

Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle α2C-adrenoceptors

(2008) A. H. Eid et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In-frame deletion in the seventh immunoglobulin-like repeat of filamin C in a family with myofibrillar myopathy

(2008) Alexey Shatunov et al.   EUROPEAN JOURNAL OF HUMAN GENETICS