The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility

Minding the gaps that link intrinsic circadian clock within the heart to its intrinsic ultradian pacemaker clocks. Focus on “The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility”

(2013) Edward G. Lakatta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Development of dilated cardiomyopathy in Bmal1-deficient mice

(2012) Mellani Lefta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Genetic variants in SCN5A promoter are associated with arrhythmia phenotype severity in patients with heterozygous loss-of-function mutation

(2012) Ji Kwon Park et al.   HEART RHYTHM

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

(2012) Darwin Jeyaraj et al.   NATURE

A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle

(2012) Xiping Zhang et al.   NUCLEIC ACIDS RESEARCH

Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic mice

(2011) Michael E. Hall et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The relationship between circadian blood pressure pattern and ventricular repolarization dynamics assessed by QT dynamicity

(2011) Sercan Okutucu et al.   BLOOD PRESSURE MONITORING

Evidence Suggesting that the Cardiomyocyte Circadian Clock Modulates Responsiveness of the Heart to Hypertrophic Stimuli in Mice

(2011) David J. Durgan et al.   CHRONOBIOLOGY INTERNATIONAL

Age-Associated Disruption of Molecular Clock Expression in Skeletal Muscle of the Spontaneously Hypertensive Rat

(2011) Mitsunori Miyazaki et al.   PLoS One

A Combined Experimental and Mathematical Approach for Molecular-based Optimization of Irinotecan Circadian Delivery

(2011) Annabelle Ballesta et al.   PLoS Computational Biology

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

Insights into sick sinus syndrome from an inducible mouse model

(2010) Stefan Herrmann et al.   CARDIOVASCULAR RESEARCH

The Cardiomyocyte Circadian Clock

(2010) David J. Durgan et al.   CIRCULATION RESEARCH

Transcriptional Repressor E4-binding Protein 4 (E4BP4) Regulates Metabolic Hormone Fibroblast Growth Factor 21 (FGF21) during Circadian Cycles and Feeding

(2010) Xin Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JTK_CYCLE: An Efficient Nonparametric Algorithm for Detecting Rhythmic Components in Genome-Scale Data Sets

(2010) Michael E. Hughes et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Cardiac ion channels in health and disease

(2009) Ahmad S. Amin et al.   HEART RHYTHM

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene

(2009) Kristin Brevik Andersson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of cell-specific circadian clocks in metabolism and disease

(2009) M. S. Bray et al.   Obesity Reviews

Cardiac sodium channelopathies

(2009) Ahmad S. Amin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Nav1.5 antisense inhibition

(2008) Victor A. Maltsev et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters

(2008) Tami A. Martino et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Restricted N-terminal truncation of cardiac troponin T: a novel mechanism for functional adaptation to energetic crisis

(2008) Han-Zhong Feng et al.   JOURNAL OF PHYSIOLOGY-LONDON

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

(2007) Molly S. Bray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY