The UDP-sugar-sensing P2Y14 receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils

Purinergic signaling and immune cell chemotaxis. Focus on “The UDP-sugar-sensing P2Y14 receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils”

(2012) Scott M. O'Grady   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors

(2012) Ross Corriden et al.   Purinergic Signalling

Rho Signaling Regulates Pannexin 1-mediated ATP Release from Airway Epithelia

(2011) Lucia Seminario-Vidal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NTPDase1 Controls IL-8 Production by Human Neutrophils

(2011) F. Kukulski et al.   JOURNAL OF IMMUNOLOGY

Protein kinase A governs a RhoA–RhoGDI protrusion–retraction pacemaker in migrating cells

(2011) Eugene Tkachenko et al.   NATURE CELL BIOLOGY

Sensing sterile injury: Opportunities for pharmacological control

(2011) Gustavo B. Menezes et al.   PHARMACOLOGY & THERAPEUTICS

Signalling and pharmacological properties of the P2Y14 receptor

(2010) T. K. Harden et al.   Acta Physiologica

Coupled Nucleotide and Mucin Hypersecretion from Goblet-Cell Metaplastic Human Airway Epithelium

(2010) Seiko F. Okada et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Purinergic Signaling: A Fundamental Mechanism in Neutrophil Activation

(2010) Y. Chen et al.   Science Signaling

Quantification of extracellular UDP-galactose

(2009) Eduardo R. Lazarowski   ANALYTICAL BIOCHEMISTRY

UDP-glucose acting at P2Y 14 receptors is a mediator of mast cell degranulation

(2009) Zhan-Guo Gao et al.   BIOCHEMICAL PHARMACOLOGY

Endoplasmic Reticulum/Golgi Nucleotide Sugar Transporters Contribute to the Cellular Release of UDP-sugar Signaling Molecules

(2009) Juliana I. Sesma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The UDP-Glucose Receptor P2RY14 Triggers Innate Mucosal Immunity in the Female Reproductive Tract by Inducing IL-8

(2009) T. Arase et al.   JOURNAL OF IMMUNOLOGY

P2X1 Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation

(2009) C. Lecut et al.   JOURNAL OF IMMUNOLOGY

Gi-Dependent Cell Signaling Responses of the Human P2Y14 Receptor in Model Cell Systems

(2009) I. P. Fricks et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Quantification of Gi-Mediated Inhibition of Adenylyl Cyclase Activity Reveals That UDP Is a Potent Agonist of the Human P2Y14 Receptor

(2009) R. L. Carter et al.   MOLECULAR PHARMACOLOGY

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Similarities between UDP-Glucose and Adenine Nucleotide Release in Yeast: Involvement of the Secretory Pathway†

(2008) Charles R. Esther et al.   BIOCHEMISTRY

Thrombin-promoted release of UDP-glucose from human astrocytoma cells

(2008) S M Kreda et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ecto-nucleoside Triphosphate Diphosphohydrolase 1 (E-NTPDase1/CD39) Regulates Neutrophil Chemotaxis by Hydrolyzing Released ATP to Adenosine

(2008) Ross Corriden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UDP Is a Competitive Antagonist at the Human P2Y14 Receptor

(2008) I. P. Fricks et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation

(2008) Vielska M. Brautigam et al.   Purinergic Signalling