Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636

The emerging role of PtdIns5P: another signalling phosphoinositide takes its place: Figure 1

(2012) Deborah L. Grainger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

PI3K signalling: the path to discovery and understanding

(2012) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Small-molecule inhibitors of the PI3K signaling network

(2011) Colleen R McNamara et al.   Future Medicinal Chemistry

The Nucleophosmin-Anaplastic Lymphoma Kinase Oncogene Interacts, Activates, and Uses the Kinase PIKfyve to Increase Invasiveness

(2011) Sophie Dupuis-Coronas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development

(2011) Ognian C. Ikonomov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New methods for capturing the mystery lipid, PtdIns5P

(2010) Jonathan M. Backer   BIOCHEMICAL JOURNAL

A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5Pand other phosphoinositides

(2010) Deborah Sarkes et al.   BIOCHEMICAL JOURNAL

Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella

(2010) Markus C Kerr et al.   EMBO JOURNAL

Phosphoinositides Direct Equine Infectious Anemia Virus Gag Trafficking and Release

(2010) Fiona Fernandes et al.   TRAFFIC

YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes

(2009) Ognian C. Ikonomov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The roles of Dok family adapters in immunoreceptor signaling

(2009) Ryuichi Mashima et al.   IMMUNOLOGICAL REVIEWS

PIKfyve-ArPIKfyve-Sac3 Core Complex

(2009) Ognian C. Ikonomov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sac3 Is an Insulin-regulated Phosphatidylinositol 3,5-Bisphosphate Phosphatase

(2009) Ognian C. Ikonomov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells

(2009) G. Guittard et al.   JOURNAL OF IMMUNOLOGY

Phosphoinositide Signaling: New Tools and Insights

(2009) Tamas Balla et al.   PHYSIOLOGY

Mammalian phosphoinositide kinases and phosphatases

(2009) Takehiko Sasaki et al.   PROGRESS IN LIPID RESEARCH

PIKfyve Regulation of Endosome-Linked Pathways

(2009) Jane de Lartigue et al.   TRAFFIC

Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3

(2008) Assia Shisheva   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Elevated levels of PtdIns5P in NPM-ALK transformed cells: Implication of PIKfyve

(2008) S. Coronas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PIKfyve: Partners, significance, debates and paradoxes

(2008) A SHISHEVA   CELL BIOLOGY INTERNATIONAL

Function and dysfunction of the PI system in membrane trafficking

(2008) Mariella Vicinanza et al.   EMBO JOURNAL

A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

(2008) Harold B J Jefferies et al.   EMBO REPORTS

ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality

(2008) Diego Sbrissa et al.   JOURNAL OF MOLECULAR BIOLOGY

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE