Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling

Rgs2 Mediates Pro-Angiogenic Function of Myeloid Derived Suppressor Cells in the Tumor Microenvironment via Upregulation of MCP-1

(2011) Kimberly C. Boelte et al.   PLoS One

Influence of cell background on pharmacological rescue of mutant CFTR

(2010) Nicoletta Pedemonte et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTRMutation

(2010) Frank J. Accurso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional Stability of Rescued ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Airway Epithelial Cells

(2009) Asta Jurkuvenaite et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics

(2009) Emeka I Igwe et al.   BMC GENOMICS

Low temperature restoring effect on F508del-CFTR misprocessing: A proteomic approach

(2009) Patricia Gomes-Alves et al.   Journal of Proteomics

Mechanisms for Rescue of Correctable Folding Defects in CFTRΔF508

(2009) Diane E. Grove et al.   MOLECULAR BIOLOGY OF THE CELL

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

(2009) Darren M Hutt et al.   Nature Chemical Biology

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen-Regulated  2-Adrenergic Receptor Hydroxylation by EGLN3 and Ubiquitylation by pVHL

(2009) L. Xie et al.   Science Signaling

CFTR Function and Prospects for Therapy

(2008) John R. Riordan   Annual Review of Biochemistry

Acute hypoxia to endothelial cells induces activating transcription factor 3 (ATF3) expression that is mediated via nitric oxide

(2008) Shih-Chung Chen et al.   ATHEROSCLEROSIS

Enhanced cell-surface stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones

(2008) Karoly Varga et al.   BIOCHEMICAL JOURNAL

Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347mutagenesis

(2008) Emanuela Caci et al.   BIOCHEMICAL JOURNAL

Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases

(2008) Ting-Wei Mu et al.   CELL

Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders

(2008) Samuel M Moskowitz et al.   GENETICS IN MEDICINE

Acridine-Based Agents with Topoisomerase II Activity Inhibit Pancreatic Cancer Cell Proliferation and Induce Apoptosis

(2007) John R. Goodell et al.   JOURNAL OF MEDICINAL CHEMISTRY