Article
Obstetrics & Gynecology
Yuan-Yuan Li, Jing Cao, Jia-Lei Li, Jun-Yan Zhu, Yong-Mei Li, De-Ping Wang, Hong Liu, Hai-Lan Yang, Yin-Fang He, Li-Yan Hu, Rui Zhao, Chu Zheng, Yan-Bo Zhang, Ji-Min Cao
Summary: This study identified high-, medium-, and low-risk clusters of patients with PE based on the severity of persistent PHTN, with each cluster exhibiting distinct clinical characteristics.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Obstetrics & Gynecology
U. Vivian Ukah, Natalie Dayan, Brian J. Potter, Aimina Ayoub, Nathalie Auger
Summary: This study found that severe maternal morbidity is associated with an increased risk of long-term mortality after pregnancy, particularly with severe cardiac complications, acute renal failure, and cerebrovascular accidents. Women with serious pregnancy complications may benefit from more intensive clinical follow-up.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Endocrinology & Metabolism
George W. Booz, Daniel Kennedy, Michael Bowling, Taprieka Robinson, Daniel Azubuike, Brandon Fisher, Karen Brooks, Pooja Chinthakuntla, Ngoc H. Hoang, Jonathan P. Hosler, Mark W. Cunningham
Summary: Inhibition of AT1-AA not only improves blood pressure and pathophysiology of PE in rats during pregnancy, but also long-term changes in blood pressure, cardiac hypertrophy, and cardiac mitochondrial function postpartum.
BIOLOGY OF SEX DIFFERENCES
(2021)
Article
Obstetrics & Gynecology
Jourdan E. Triebwasser, Matthew K. Janssen, Harish M. Sehdev
Summary: This study aimed to determine the proportion of women with documented counseling on risks and transitions of care after hypertensive disorders of pregnancy at the postpartum visit. Results showed that only 25% of women received counseling on hypertensive disorders of pregnancy during postpartum visits, indicating a need for improvement in postpartum care for these patients.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Obstetrics & Gynecology
Kathrin Hassdenteufel, Mitho Muller, Raphael Gutsfeld, Maren Goetz, Armin Bauer, Markus Wallwiener, Sara Y. Brucker, Stefanie Joos, Miriam Giovanna Colombo, Sabine Hawighorst-Knapstein, Ariane Chaudhuri, Gudula Kirtschig, Frauke Saalmann, Stephanie Wallwiener
Summary: Preeclampsia increases the risk of developing chronic hypertension and cardiovascular disease in women, especially those with recurrent preeclampsia. Future medical guidelines should take this potential risk into account.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Review
Medicine, General & Internal
Jarawee Sukmanee, Tippawan Liabsuetrakul
Summary: Women with a history of hypertensive disorders of pregnancy (HDP) have an increased risk of cardiovascular diseases (CVDs) in later life, especially within the first 5 years postpartum. Preeclamptic women have a higher risk of CVDs compared to women with normotensive pregnancies.
Article
Medicine, General & Internal
Samantha J. Benton, Erika E. Mery, David Grynspan, Laura M. Gaudet, Graeme N. Smith, Shannon A. Bainbridge
Summary: Preeclampsia is associated with increased risk of cardiovascular disease in later life. Placental lesions may be a useful tool for identifying high-risk women. The study found that high-risk women had more severe maternal vascular malperfusion lesions in the placenta, which were associated with a 3-fold increased risk of cardiovascular disease screening at 6 months postpartum.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Peripheral Vascular Disease
Kavia Khosla, Sarah Heimberger, Kristin M. Nieman, Avery Tung, Sajid Shahul, Anne Cathrine Staff, Sarosh Rana
Summary: Women with a history of hypertensive disorders of pregnancy have higher rates of long-term cardiovascular events, and the American Heart Association calls for early identification and risk reduction by physicians. This review discusses the epidemiology, pathophysiology, and outcomes of HDP-associated cardiovascular disease.
Article
Obstetrics & Gynecology
Snigdha Alur-Gupta, Mary Regina Boland, Kurt T. Barnhart, Mary D. Sammel, Anuja Dokras
Summary: The study reveals that women with polycystic ovary syndrome are at increased risk of cardiovascular and psychiatric complications during the postpartum period, showing significantly higher odds of cardiovascular disease complications and depression than those without the syndrome.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Eirin Arntzen, Ranveig Josendal, Heidi Linn Sandsaeter, Julie Horn
Summary: This qualitative study explores the perspectives and preferences of women with preeclampsia regarding postpartum follow-up. The findings highlight the importance of systematic postpartum care for women after a pregnancy complicated by preeclampsia. Standardized guidelines and routine invitations to postpartum care should be further explored. Additionally, understanding healthcare professionals' experiences is crucial to ensure their engagement in postpartum care after complicated pregnancies.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Cardiac & Cardiovascular Systems
Guan Wang, Yanbo Zhang, Sijin Li, Jun Zhang, Dongkui Jiang, Xiuzhen Li, Yulin Li, Jie Du
Summary: This study developed a model based on machine learning to predict postpartum cardiovascular risk in preeclamptic women. The Random Forest algorithm showed the best performance in predicting cardiovascular risk, with good calibration and high net benefit.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Alexa Campbell, Kaitlyn K. Stanhope, Marissa Platner, Naima T. Joseph, Denise J. Jamieson, Sheree L. Boulet
Summary: The study found that the postpartum blood pressure screening attendance rate was low among women with hypertensive disorders of pregnancy, highlighting the need for further research and creative solutions to address barriers at the individual, provider, and system levels.
JOURNAL OF WOMENS HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Parya Amini, Mehran Amrovani, Zohre Saleh Nassaj, Parisa Ajorlou, Aiyoub Pezeshgi, Bahareh Ghahrodizadehabyaneh
Summary: Preeclampsia (PE) is a complication during pregnancy that poses a threat to pregnant women, with high blood pressure being one of its main symptoms. Studies have shown that PE can increase the risk of developing cardiovascular disease and mortality. By understanding the signaling pathways involved in blood pressure regulation, appropriate treatment strategies can be developed to reduce blood pressure in PE individuals, thus reducing the risk of cardiovascular disease and mortality.
CARDIOVASCULAR TOXICOLOGY
(2022)
Review
Medicine, General & Internal
Courtney Bisson, Sydney Dautel, Easha Patel, Sunitha Suresh, Patricia Dauer, Sarosh Rana
Summary: Preeclampsia is a disease that has wide-ranging effects on the body's organ systems, with consequences lasting beyond the immediate postpartum period. Current research aims to understand the pathophysiology of preeclampsia for accurate screening and treatment. Preeclampsia impacts maternal morbidity and mortality in the cardiovascular system and other organs, with effects persisting after pregnancy. This review discusses the current understanding of preeclampsia's pathophysiology and ways to improve overall outcomes.
FRONTIERS IN MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Veronica Giorgione, Asma Khalil, Jamie O'Driscoll, Basky Thilaganathan
Summary: This study assessed the effectiveness of peripartum screening in predicting CHT after HDP and found that a prediction model combining clinical and echocardiographic features showed excellent accuracy in identifying women at risk of persistent hypertension after HDP.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Obstetrics & Gynecology
Logan C. Barr, Kiera Liblik, Amer M. Johri, Graeme N. Smith
Summary: Preeclampsia is a hypertensive pregnancy complication that is associated with adverse maternal health outcomes. However, the exact intermediary mechanisms for this association have not been established. This review summarizes the cardiovascular changes associated with prior preeclampsia and explores their potential link to future maternal disease.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Emma J. Wilson, Jessica Pudwell, Graeme N. Smith
Summary: This study shows the poor outcomes associated with prenatal cannabis use. With the legalization of cannabis in Canada, it is crucial to increase awareness of its effects during pregnancy. The study found a potential knowledge gap among 9%-19% of participants who believed that cannabis posed no harm to pregnant individuals or fetuses. Minor changes could improve the effectiveness of educational resources.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
(2022)
Article
Obstetrics & Gynecology
Sydney B. Flatt, Jessica Pudwell, Graeme N. Smith
Summary: The study shows that women who attended the Maternal Health Clinic experienced improvements in interpregnancy weight reduction, fewer type II diabetes diagnoses, and later gestational age at delivery. However, there were no differences in recurrence rates of GDM or HDP between attendees and non-attendees.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
(2022)
Article
Cardiac & Cardiovascular Systems
Anna C. O'Kelly, Erin D. Michos, Chrisandra L. Shufelt, Jane V. Vermunt, Margo B. Minissian, Odayme Quesada, Graeme N. Smith, Janet W. Rich-Edwards, Vesna D. Garovic, Samar R. El Khoudary, Michael C. Honigberg
Summary: In addition to conventional risk factors, women also face sex-specific risk factors for cardiovascular disease. Key stages of a woman's reproductive history, such as early and late menarche, polycystic ovary syndrome, infertility, adverse pregnancy outcomes, and absence of breastfeeding, are associated with increased future cardiovascular disease risk. The menopause transition period also represents an accelerated cardiovascular disease risk, with timing, mechanism, and symptoms of menopause playing a role. Differences in conventional risk factors explain some, but not all, of the observed associations between reproductive history and cardiovascular disease; further research is needed to understand hormonal effects and unique sex-specific mechanisms. A history of reproductive risk factors provides an opportunity for comprehensive screening, refinement of risk assessment, and implementation of prevention strategies to optimize women's long-term cardiometabolic health.
CIRCULATION RESEARCH
(2022)
Article
Obstetrics & Gynecology
Allison DeLong, Lindsay Shirreff, Ally Murji, John J. Matelski, Jessica Pudwell, Olga Bougie
Summary: The study aims to identify patient characteristics associated with postoperative complications or readmissions after hysterectomy for a benign indication. The findings indicate that factors such as previous cesarean delivery, American Society of Anesthesiologists class = 3, preoperative anemia, and laparotomic approach are associated with increased odds of complications. In addition, perioperative complications, preoperative anemia, and vaginal or laparotomic approach are associated with increased odds of emergency room visits or hospital readmissions.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2022)
Editorial Material
Obstetrics & Gynecology
Graeme N. Smith, Jocelynn L. Cook
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
(2022)
Editorial Material
Obstetrics & Gynecology
Graeme N. Smith, Jocelynn L. Cook
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA
(2022)
Article
Obstetrics & Gynecology
Sumaiya Adam, Harold David McIntyre, Kit Ying Tsoi, Anil Kapur, Ronald C. Ma, Stephanie Dias, Pius Okong, Moshe Hod, Liona C. Poon, Graeme N. Smith, Lina Bergman, Esraa Algurjia, Patrick O'Brien, Virna P. Medina, Cynthia Maxwell, Lesley Regan, Mary L. Rosser, Bo Jacobsson, Mark A. Hanson, Sharleen L. O'Reilly, Fionnuala M. McAuliffe
Summary: Gestational diabetes (GDM) affects approximately 17 million pregnancies worldwide. Women with a history of GDM are at a significantly higher risk of developing type 2 diabetes and cardiovascular disease compared to those without prior GDM. Although prevention and delayed progression of GDM to type 2 diabetes is possible, it is not widely practiced. Considering the increasing rates of type 2 diabetes and CVD in women globally, it is crucial to utilize pregnancy as an opportunity for early identification and preventive intervention.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Cynthia Maxwell, Rachelle Shirley, Amy C. O'Higgins, Mary L. Rosser, Patrick O'Brien, Moshe Hod, Sharleen L. O'Reilly, Virna P. Medina, Graeme N. Smith, Mark A. Hanson, Sumaiya Adam, Ronald C. Ma, Anil Kapur, Harold David McIntyre, Bo Jacobsson, Liona C. Poon, Lina Bergman, Lesley Regan, Esraa Algurjia, Fionnuala M. McAuliffe
Summary: Obesity is a chronic, progressive, relapsing, and treatable neurobehavioral disease that affects women's health and requires a focus on optimizing health outcomes rather than weight loss. Appropriate and sensitive language, as well as trauma-informed care, is necessary when discussing obesity.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Liona C. Poon, Long Nguyen-Hoang, Graeme N. Smith, Lina Bergman, Patrick O'Brien, Moshe Hod, Pius Okong, Anil Kapur, Cynthia Maxwell, Harold David McIntyre, Bo Jacobsson, Esraa Algurjia, Mark A. Hanson, Mary L. Rosser, Ronald C. Ma, Sharleen L. O'Reilly, Lesley Regan, Sumaiya Adam, Virna P. Medina, Fionnuala M. McAuliffe
Summary: Hypertensive disorders of pregnancy (HDP) are the leading cause of maternal and perinatal morbidity and mortality, accounting for 16% of maternal deaths in high-income countries and approximately 25% in low- and middle-income countries. HDP increases the risk of future cardiovascular disease. Failure to achieve normal cardiovascular adaptation during pregnancy is associated with the development of HDP. Women with a history of HDP may experience long-term hemodynamic alterations, predisposing them to cardiovascular morbidity and mortality. Therefore, it is crucial to identify underlying cardiovascular risk factors during pregnancy and the postpartum period and develop strategies for lifestyle and therapeutic interventions to reduce the risk of future cardiovascular disease in women with a history of HDP.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Natalie Dayan, Graeme Smith, Atanas Nedelchev, Haim Abenhaim, Richard Brown, Deborah Da Costa, Suhad Ali, Jesseca Perlman, Tuong-Vi Nguyen, Cindy-Lee Dennis, Wael Abdelmageed, Sonia Semenic
Summary: This study aims to test whether a self-efficacy enhancing breastfeeding intervention can improve breastfeeding outcomes and lower postpartum blood pressure in women with hypertensive disorders of pregnancy (HDP). If effective, this enhanced breastfeeding support can be widely implemented in women lactating after HDP.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Ainsley M. Johnstone, Jessica Pudwell, Christina M. Ackerman-Banks, Lisbet S. Lundsberg, Heather S. Lipkind, Graeme N. Smith
Summary: Patients with a hypertensive disorder of pregnancy are at increased risk of cardiovascular disease postpartum, and high-sensitivity C-reactive protein can be used as a marker to identify this risk. The study found that patients with elevated levels of high-sensitivity C-reactive protein in the postpartum period have a higher risk of metabolic syndrome and cardiovascular disease within 6 to 12 months.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Christina M. Ackerman-Banks, Jessica Pudwell, Lisbet Lundsberg, Heather S. Lipkind, Graeme N. Smith
Summary: This study aimed to determine if the use of first-degree family history of cardiovascular disease or chronic hypertension could better identify individuals who need postpartum cardiovascular risk screening. The results showed that individuals with a positive family history of chronic hypertension, myocardial infarction, or stroke were more likely to be diagnosed with chronic hypertension and had elevated cardiovascular disease risk.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Letter
Cardiac & Cardiovascular Systems
Graeme N. Smith, Natalie Dayan
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)