The Institute of Medicine Guidelines for Gestational Weight Gain after a Diagnosis of Gestational Diabetes and Pregnancy Outcomes

Objective The objective of this study was to assess the impact of gestational weight gain outside the Institute of Medicine (IOM) recommendations after the diagnosis of gestational diabetes (GDM) on perinatal outcomes. Materials and Methods This was a retrospective cohort study. Women were classified as gestational weight gain (GWG) within, less than, or greater than 10M recommendations for body mass index as calculated by gestational weight gain per week after a diagnosis of GDM. Outcomes assessed were preeclampsia, cesarean delivery, A2 GDM, birth weight, small for gestational age (SGA), large for gestational age (LGA), macrosomia, and preterm delivery. Groups were compared using analysis of variance and chisquare test for trend, as appropriate. Backward stepwise logistic regression was used to adjust for significant confounding factors. Results Of 635 subjects, 92 gained within, 175 gained less than, and 368 gained more than IOM recommendations. The risk of cesarean delivery and A2 GDM was increased in those gaining above the 10M recommendations compared with within. For every 1-16/week increase in weight gain after diagnosis of GDM, there was a 36 to 83% increase in the risk of preeclampsia, cesarean delivery, A2 GDM, macrosomia, and LGA, without decreases in SGA or preterm delivery. Conclusion Weight gain more than the IOM recommendations per week of gestation after a diagnosis of GDM is associated with adverse pregnancy outcomes.