Article
Obstetrics & Gynecology
Aalok R. Sanjanwala, Victoria C. Jauk, Gabriella D. Cozzi, David A. Becker, Lorie M. Harper, Brian M. Casey, Alan T. Tita, Akila Subramaniam
Summary: The study aimed to compare outcomes in women with severe preeclampsia before and after the implementation of guidelines. The results showed that perinatal outcomes were similar before and after the implementation of severe preeclampsia management guidelines at the institution.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Health Care Sciences & Services
Kaori Moriuchi, Kaoru Kawasaki, Maako Hayashi, Akihiko Ueda, Yukio Yamanishi, Haruta Mogami, Kohei Fujita, Reona Shiro, Yoshie Yo, Masaki Mandai, Noriomi Matsumura
Summary: Long-term magnesium sulfate administration for patients with preeclampsia without severe hypertension may prevent a decrease in antithrombin activity and improve the disease state of preeclampsia.
Article
Obstetrics & Gynecology
Jesrine Hong, Kylie Crawford, Anthony O. Odibo, Sailesh Kumar
Summary: This study evaluated the risks of stillbirth, neonatal mortality, and severe neonatal morbidity in relation to the timing of birth between 37 and 40 weeks of gestation. The results suggest that the optimal time of birth varies depending on the infant's birthweight centile, with 37 to 37+6 weeks being optimal for infants below the third centile, 38 to 38+6 weeks for infants between the third and tenth centiles and above the ninetieth centile, and 39 weeks for infants in other birthweight centiles.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Multidisciplinary Sciences
Marta David Rocha de Moura, Paulo Roberto Margotto, Karina Nascimento Costa, Maria Rita Carvalho Garbi Novaes
Summary: This study found that gestational hypertension may have a negative impact on premature newborns, leading to lower birth weights, increased risk of SGA, higher mortality and enterocolitis rates in the neonatal period. However, there were no significant differences in weight and survival at 18 months of age.
Article
Obstetrics & Gynecology
Florence Cadoret, Paul Guerby, Marie Cavaignac-Vitalis, Christophe Vayssiere, Olivier Parant, Fabien Vidal
Summary: HELLP syndrome is a rare and severe pregnancy complication with controversial management strategies. Identifying baseline parameters predictive of disease evolution is crucial in determining the appropriate obstetrical approach for each patient.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Ji Yeon Lee, Seung Mi Lee, Mina Jeong, Sohee Oh, Subeen Hong, Seung-Ah Choe, Jong Kwan Jun
Summary: Reproductive endocrinologists suggest selective multifetal pregnancy reduction to save at least one or two babies in triplet pregnancies. However, recent advancements in obstetric and neonatal care may change the outcomes. This study compared the outcomes of expectant management and reduction to twins in triplet pregnancies, showing that expectant management could improve neonatal survival and reduce the risk of developmental delay.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Medicine, General & Internal
Jiao Yi, Lei Chen, Xianglian Meng, Yi Chen
Summary: This study aimed to identify factors affecting expectant management of early-onset preeclampsia and evaluate the correlation between expectant treatment and fetal growth restriction. The duration of 24-h proteinuria showed a negative correlation with expectant treatment, but expectant treatment could not improve the occurrence of fetal growth restriction.
ANNALS OF MEDICINE
(2022)
Article
Medicine, General & Internal
Roxana Elena Bohiltea, Ana Maria Cioca, Vlad Dima, Ionita Ducu, Corina Grigoriu, Valentin Varlas, Florentina Furtunescu
Summary: Prelabor preterm rupture of the membranes (PPROM) is an important cause of neonatal morbidity and mortality. Expectant management can reduce the incidence of complications in premature infants, but the benefit depends on the gestational age at which the membranes ruptured and the medical conduct during the latency period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Anuchit Inta, Theera Tongsong, Kasemsri Srisupundit
Summary: This study aimed to investigate the pregnancy outcomes of conservative treatment for preeclampsia with severe features. The results showed that the rate of pregnancy prolongation with conservative management was 65%, with a median prolongation time of 2.9 days. The high urine protein/creatinine ratio (UPCI) at admission was found to be an independent factor for less than 48-hour pregnancy prolongation with conservative treatment. However, there were no significant differences in maternal and fetal outcomes between the two groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, Research & Experimental
Sarah M. Ghazali, Ohoud A. AlGhamdi, Nora N. Sahly, Kholoud K. Nagadi, Reem M. Khalifah, Sedrah M. Hanbazaza, Danah I. Krimli, Sarah M. Allaf, Renad A. Turkistani, Haifa'a A. Mansouri
Summary: This study assessed the optimal management approach for patients with preeclampsia according to the newly defined 2020 American College of Obstetrics and Gynecology guideline. The results showed that aggressive management based on disease severity may improve maternal and perinatal outcomes.
Review
Obstetrics & Gynecology
Christos Chatzakis, Anastasios Liberis, Apostolos Zavlanos, Stamatis Petousis, Evangelia Tsakmaki, Konstantinos Dinas, Alexandros Sotiriadis
Summary: This study compared expectant management with immediate delivery in women with non-severe preeclampsia at the late preterm period. Immediate delivery increased the risk of neonatal intensive care unit (NICU) admission but decreased the risk of composite adverse maternal outcome.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Review
Obstetrics & Gynecology
Alice Beardmore-Gray, Paul T. Seed, Jessica Fleminger, Eva Zwertbroek, Thomas Bernardes, Ben W. Mol, Cheryl Battersby, Corine Koopmans, Kim Broekhuijsen, Kim Boers, Michelle Y. Owens, Jim Thornton, Marcus Green, Andrew H. Shennan, Henk Groen, Lucy C. Chappell
Summary: This individual participant data meta-analysis compared planned delivery to expectant management in women with preeclampsia. The results showed that planned delivery from 34 weeks gestation onward reduced the risk of maternal morbidity and the likelihood of the infant being born small for gestational age. However, it also increased the risk of short-term neonatal respiratory morbidity.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Letter
Medicine, General & Internal
John van den Anker
Summary: This article discusses the management of patent ductus arteriosus (PDA) and finds that expectant management is noninferior to early ibuprofen treatment in preventing complications and death. However, the study did not consider the fact that a significant percentage of infants in both groups also received acetaminophen, which has been found to have similar effectiveness to ibuprofen for PDA closure.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Obstetrics & Gynecology
Courtney Martin, James Pappas, Kim Johns, Heather Figueroa, Kevin Balli, Ruofan Yao
Summary: The implementation of a semiautonomous treatment algorithm for severe hypertension led to more pregnant and postpartum patients receiving timely antihypertensive therapy, improving care quality and equity.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Sathida Chantanavilai, Kiattisak Kongwattanakul, Ratana Komwilaisak, Piyamas Saksiriwuttho, Sukanya Chaiyarach, Chatuporn Duangkam, Suppasiri Hayakungchat, Kaewjai Thepsuthammarat
Summary: This study analyzed the incidence of early-onset severe features preeclampsia and compared the maternal complications and perinatal outcomes between expectant and immediate delivery management. It found that gestational age over 30 weeks and uric acid level below 5.5 mg/dL were significant factors for successful expectant management.
PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH
(2022)