Article
Multidisciplinary Sciences
Bowen Zhang, Xingmei Dong, Yi Sun
Summary: The necessity of internal limiting membrane (ILM) peeling for patients with idiopathic epiretinal membrane (iERM) was further evaluated. The study found that ILM peeling did not significantly improve the best-corrected visual acuity (BCVA), central macular thickness (CMT), but it did reduce the recurrence rate.
Article
Ophthalmology
Umberto Lorenzi, Joel Mehech, Tommaso Caporossi, Mario R. Romano, Rocco De Fazio, Eric Parrat, Frederic Matonti, Paolo Mora
Summary: The study found that AILMT and hAM were the most frequently performed surgeries with high closure rates and significant functional improvement. Preoperative BCVA was correlated with final BCVA, and the minimum FTMH diameter may guide treatment choices.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Medicine, General & Internal
Akari Kimura, Hisanori Imai, Yukako Iwane, Maya Kishimoto, Yasuyuki Sotani, Hiroko Yamada, Wataru Matsumiya, Akiko Miki, Sentaro Kusuhara, Makoto Nakamura
Summary: This new technique can effectively remove sub-internal limiting membrane hemorrhage without peeling the internal limiting membrane, resulting in improved visual acuity and prevention of full-thickness macular hole formation in patients with submacular hemorrhage caused by retinal arterial macroaneurysm rupture.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Tommaso Rossi, Carlandrea Trillo, Guido Ripandelli
Summary: The study found that autologous internal limiting membrane flap treatment for recurrent idiopathic macular holes resulted in a higher closure rate, smaller residual inner segment/outer segment line interruption, and better visual acuity compared to the previous standard of care.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Xujia Liu, Jinqu Huang, Ruiqin Zhou, Zehua Jiang, Haoyu Chen, Weiqi Chen, Tsz Kin Ng, Zhenggen Wu, Guihua Zhang
Summary: This study evaluated the outcomes of ILM peeling and the inverted ILM flap technique for rhegmatogenous retinal detachment with macular hole. The inverted ILM flap technique had a higher Type 1 closure rate and similar rates of retinal reattachment and visual improvement compared to ILM peeling.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2022)
Article
Medicine, General & Internal
Huang-Fang Ying, Shuang-Qing Wu, Wei-Ping Hu, Li-Yang Ni, Zi-Long Zhang, Yong-Gen Xu
Summary: This case report describes the successful closure of a macular hole (MH) secondary to pathological myopia using vitrectomy combined with residual internal limiting membrane (ILM) covering and autologous blood. The patient initially underwent fovea-sparing ILM peeling, but an MH developed and gradually expanded after the surgery. A second vitrectomy with residual ILM covering and autologous blood resulted in the closure of the MH and improvement in visual acuity.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Ophthalmology
Nurullah Kocak, Volkan Yeter, Hakki Birinci
Summary: The study compares the outcomes of conventional ILM peeling and temporal inverted ILM flap technique for large full-thickness macular holes. The results suggest that the temporal inverted ILM flap technique is more effective in terms of hole closure rate, BCVA improvement, and restoration of the outer retinal layers.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Dhananjay Shukla, Jay Kalliath
Summary: This study reports a modified internal limiting membrane (ILM) peeling surgery tailored to the shape of macular holes, aiming to improve closure rates. The results showed that the macular holes were horizontally oval in shape, and a corresponding enlargement of the ILM rhexis yielded excellent anatomical and satisfactory visual outcomes.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Letter
Ophthalmology
Elizabeth D. Marlow, Saaquib R. Bakhsh, Devasis N. Reddy, Nathan D. Farley, George A. Williams, Tamer H. Mahmoud
Summary: The use of an ILM flap for large and myopic macular holes has been proven to increase the success rate of single surgeries, and incorporating an epiretinal membrane into the flap improves the outcome.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Xunyi Gu, Zizhong Hu, Huiming Qian, Silvia Fransisca, Aime Mugisha, Jingfan Wang, Zhengyu Zhang, Weiwei Zhang, Jiangdong Ji, Qinghuai Liu, Ping Xie
Summary: In the treatment of macular hole retinal detachment in highly myopic eyes, the modified perfluorocarbon liquid-assisted inverted ILM flap technique was more effective in achieving macular hole closure and significantly improving visual acuity compared to standard ILM peeling.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Ophthalmology
Kevin Y. Zhang, Thomas Johnson
Summary: Basement membranes play crucial roles in establishing, maintaining, and separating tissues, as well as providing growth and signaling substrates for nearby resident cells. The internal limiting membrane (ILM) at the ocular vitreoretinal interface is essential for normal retinal development but dispensable in adulthood. Furthermore, the ILM may hinder novel ocular therapies.
EXPERIMENTAL EYE RESEARCH
(2021)
Article
Ophthalmology
Bianca Pacini, Daniela Bacherini, Alfonso Savastano, Stanislao Rizzo, Tomaso Caporossi
Summary: The study compared the macular microstructures of eyes treated with autologous internal limiting membrane (ILM) transplant and human Amniotic Membrane (hAM) plug transplant for failed macular holes (FMH), revealing important differences in the cellular mechanism underlying tissue remodelling in the two techniques. Additional validation with a larger patient sample and longer follow-up is needed.
ACTA OPHTHALMOLOGICA
(2022)
Article
Ophthalmology
Tian Tian, Hongsheng Tan, Xiuyu Zhu, Xiang Zhang, Peiquan Zhao
Summary: This study compared the functional and anatomical outcomes of peeled internal limiting membrane reposition and traditional internal limiting membrane peeling for idiopathic macular hole. The results showed that BCVA in the reposition group was significantly better than the peeling group at 6 months postoperatively. There was no significant difference in the closure rate of macular hole between the two groups. The reposition group had smaller inner retinal dimpling and greater tissue thickness compared to the peeling group.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2023)
Article
Ophthalmology
Elizabeth D. Marlow, Saaquib R. Bakhsh, Devasis N. Reddy, Nathan D. Farley, George A. Williams, Tamer H. Mahmoud
Summary: The purpose of this study was to assess the closure rate of large full-thickness macular holes (FTMH) associated with epiretinal membrane (ERM) using a combined epiretinal and internal limiting membrane retracting door flap. The study found that most patients achieved closure of the FTMH and showed improved visual acuity postoperatively.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Rubina Rahman, Mohammad Waseem Sarfraz, Mohamad El-Wardani
Summary: The study compared the outcomes of inverted internal limiting membrane flap (ILMF) technique and complete ILM peeling (ILMP) in nonposturing surgery for large macular holes. Both techniques resulted in successful closure of the holes postoperatively, with ILMP showing statistically significant improvement in visual acuity compared to ILMF. Postoperative nonposturing did not compromise surgical success in both groups.
JOURNAL OF VITREORETINAL DISEASES
(2022)
Editorial Material
Ophthalmology
David Cui, Ian J. Saldanha, Gavin Li, Priya M. Mathews, Michael X. Lin, Esen K. Akpek
Summary: This article reports on the heterogeneity in methodology of clinical trials submitted to the US Food and Drug Administration for approval of topical dry eye treatments. Multiple outcome measures were used in these trials, highlighting the need for standardized assessment tools to optimize the evaluation and comparison of therapeutic benefits.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Adanna Udeh, Dana Huh, Terri Young, O'rese Knight, Fasika Woreta
Summary: This study examines the rates and trends of faculty promotions within the field of ophthalmology, with a focus on the rates of promotion among underrepresented in medicine (URiM) faculty. The results show that Black faculty had lower promotion rates and were more likely to leave academic medicine, highlighting the need for strategies and policies to address equity in promotion rates and retention of URiM faculty in academic ophthalmology.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Ursula Greferath, Erica Fletcher, Judy Savige, Heather G. Mack
Summary: Retinal drusen are uncommon in IgA nephropathy, but they resemble drusen found in age-related macular degeneration. The IgA-staining deposits in the drusen are likely related to systemic deposition of IgA. The nature of cystic spaces in the drusen is still unknown. Further research on the retinas of people with glomerulonephritis is recommended.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Andrew Mihalache, Ryan S. Huang, Nikhil S. Patil, Marko M. Popovic, Ashwin Mallipatna, Peter J. Kertes, Rajeev H. Muni, Radha P. Kohly
Summary: This study examines sociodemographic predictors of poor vision in children and adolescents in the US. The findings suggest that factors such as affordability of medical care, public health insurance, age, and parental education level are associated with vision difficulty. Addressing these disparities through public health policies is crucial for achieving equity in vision health.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Johannes Birtel, Richard Caswell, Samantha R. De Silva, Philipp Herrmann, Salwah Rehman, Andrew J. Lotery, Omar A. Mahroo, Michel Michaelides, Andrew R. Webster, Robert E. Maclaren, Peter Charbel Issa
Summary: The study investigated the phenotype, variability, and penetrance of IMPG2-related maculopathy. The results showed that mono-allelic IMPG2 variants could result in haploinsufficiency manifesting as a maculopathy with variable penetrance and expressivity. Family members of patients with IMPG2-related retinitis pigmentosa may also present with vitelliform lesions. The maculopathy is usually limited to the fovea and is associated with moderate visual impairment.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Colas Nils Authie, Mylene Poujade, Alireza Talebi, Alexis Defer, Ariel Zenouda, Cecilia Coen, Saddek Mohand-Said, Philippe Chaumet-Riffaud, Isabelle Audo, Jose-Alain Sahel
Summary: MOST has been validated as a reliable mobility test for measuring the movement ability of patients with vision impairments in both real and virtual environments.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Maria Krisch, Jordan Ueberroth, Neha Gupta, Stephen Merriam, Mark p. Breazzano
Summary: Orbeez-related ocular trauma can lead to severe visual morbidity and various intraocular sequelae. Adolescents may be at higher risk for posterior segment complications. Elevated IOP and hyphema at initial presentation may indicate a need for more aggressive interventions.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Jaron Pruett, Kelly Ruland, Sean Donahue
Summary: The study aimed to validate or refute the hypothesis that infants with birthweight over 750 g and gestational age over 27 weeks, who did not have retinopathy of prematurity (ROP) at 37 weeks, would not develop treatable ROP. The findings of the study supported the termination of examination at 37 weeks in infants meeting these criteria, as the value of continued screening was minimal.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Emily Sun, Jing Tian, Loaah Eltemsah, Divya Srikumaran, Grace Sun, Jessica Chow, Fasika Woreta
Summary: This study aims to evaluate the research productivity of ophthalmology residency applicants and identify differences in productivity based on gender and race. The findings reveal that women have similar or higher research outputs compared to men, while self-identified underrepresented in medicine (URiM) students have lower research outputs in ophthalmology. Therefore, greater mentorship and support for URiM students are needed to promote the recruitment of diverse trainees in ophthalmology programs.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Isaac A. Bernstein, Ann Caroline Fisher, Kuldev Singh, Sophia Y. Wang
Summary: This study aims to investigate the association between visual field loss and frailty in a nationally representative cohort of US adults.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
