Article
Multidisciplinary Sciences
Sato Uematsu, Hirokazu Sakaguchi, Kaori Sayanagi, Yasushi Ikuno, Ayako Yokoyama, Tomoko Asai, Yoko Fukushima, Chikako Hara, Susumu Sakimoto, Kohji Nishida
Summary: The study investigated the relationship between choriocapillaris flow deficit (CFD) and high myopia-related choroidal neovascularization (CNV), finding that the size of CFD and CNV flow signal area are useful indicators of CNV activity, helping to determine treatment timing. The results suggest that both CFD area and CNV flow signal size play a significant role in assessing CNV activity in eyes with myopic CNV.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, Research & Experimental
Hua Zhong, Qingqing Dong, Qing Cun, Guangyu He, Yijin Tao, Keyao Song, Yunqing Lu, Qin Zhu, Xi Chen, Qin Chen
Summary: This study identified a positive correlation between peripapillary vessel density (pVD) and visual field mean sensitivity (VFMS) in healthy myopic eyes. This correlation was particularly strong in highly myopic eyes.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Ophthalmology
Xinxin Hu, Kunte Shang, Xiaoxiao Chen, Xinghuai Sun, Yi Dai
Summary: The study investigated microvasculature in subzones of parapapillary atrophy in healthy myopic eyes using OCT angiography. Topographic differences in superficial radial peripapillary capillary and choroidal microvasculature were found among subzones of parapapillary atrophy, suggesting a microcirculatory deficiency in the beta zone of parapapillary atrophy in myopic eyes.
Article
Multidisciplinary Sciences
Naoki Soga, Shin Tanaka, Maiko Inoue, Tatsuya Inoue, Atsushi Hayashi, Eugene de Juan Jr, Kazuaki Kadonosono
Summary: This study compared macular vessel density in CRAO eyes treated with retinal arterial cannulation and standard treatment. The cannulation group showed significant improvement in macular vessel density after 7 days, while the standard treatment group did not show significant improvement. After one month, the cannulation group had significantly improved visual acuity compared to the initial visit after the onset.
SCIENTIFIC REPORTS
(2023)
Article
Ophthalmology
Emanuele Crincoli, Silvia Ferrara, Alexandra Miere, Riccardo Sacconi, Marco Battista, Fiammetta Catania, Eric H. H. Souied, Giuseppe Querques
Summary: This study aims to investigate the correlation between the AI-measured area of the lacquer cracks (LC) and the occurrence of choroidal neovascularization (CNV) in pathologic myopia patients. The study found that larger LC area is associated with a higher probability of CNV development, and the faster the increase in LC area, the earlier the onset of CNV.
Article
Medicine, General & Internal
Yijing Chen, Jianbo Mao, Ziyi Xiang, Zhengxi Zhang, Shian Zhang, Sulan Wu, Lijun Shen
Summary: This study aimed to investigate the characteristics of retinal microvasculature in fellow eyes of patients with unilateral retinoblastoma (RB) after intra-arterial chemotherapy (IAC) using optical coherence tomography angiography. The results showed that the vascular density of deep capillary plexus (DCP) was significantly lower in the IAC and IAC + intravenous chemotherapy (IVC) groups compared to the control group. Further studies with larger sample sizes are needed to determine the clinical significance of these findings.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
Jing Liu, Shuang Song, Xiaobing Yu
Summary: This study found that baseline morphological features of myopic choroidal neovascularization (mCNV) can predict the shrinkage of the lesion in eyes treated with anti-vascular endothelial growth factor. Smaller mCNV area, shorter total vessel length, and higher end point density were associated with greater shrinkage. Higher end point density was particularly associated with shrinkage in treatment-naive lesions.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2022)
Article
Ophthalmology
Shiqi Xie, Yuxin Fang, Ran Du, Yuka Onishi, Tae Yokoi, Muka Moriyama, Takashi Watanabe, Kyoko Ohno-Matsui
Summary: Approximately 30% of eyes with myopic MNVs were found to have dilated choroidal veins below or around the MNV. The study suggests that an MNV might be a vascular unit consisting of short posterior ciliary arteries, afferent arterioles, efferent venules, and DCVs.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Sooyeon Choe, Yoon Ha Joo, Yong Woo Kim, Young Kook Kim, Jin Wook Jeoung, Jung Chan Lee, Ki Ho Park
Summary: Little is known about the myopic characteristics of lamina cribrosa (LC) curvature. As such, this study investigated the nasal and temporal LC curvatures in myopia. The results showed that myopic eyes had a smaller temporal LC curvature and a larger nasal LC curvature compared to non-myopic eyes.
SCIENTIFIC REPORTS
(2022)
Article
Physiology
Huan Luo, Jinfu Sun, Lan Chen, Dandan Ke, Zheng Zhong, Xi Cheng, Huimin Yu, Xufang Sun
Summary: This study investigated the changes in three-dimensional choroidal thickness, choroidal vessel volume, and choroidal vessel index in young myopic adults using swept-source optical coherence tomography angiography (SS-OCTA). The results showed that these indicators gradually decreased as the degree of myopia increased. The changes were more significant in the nasal quadrant of the macula and the temporal and inferior quadrants of the optic disc.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Un Chul Park, Eun Kyoung Lee, Bo Hee Kim, Baek-Lok Oh
Summary: The study found that in highly myopic eyes, choroidal and scleral thickness are associated with ocular factors such as axial length and macular curvature. Particularly, the choroid and sclera were thinner in eyes with posterior staphyloma and more severe myopic maculopathy.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Yun Hsia, Shih-Wen Wang, Chien-Jung Huang, Kuo-Chi Hung, Muh-Shy Chen, Tzyy-Chang Ho
Summary: The study evaluated factors associated with asymmetric myopic atrophic maculopathy in highly myopic patients and found that utilizing various eye imaging technologies can predict the severity of MAM.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Monica Ravenstijn, Elon H. C. van Dijk, Annechien E. G. Haarman, Talia R. Kaden, Koenraad A. Vermeer, Camiel J. F. Boon, Lawrence A. Yannuzzi, Caroline C. W. Klaver, Suzanne Yzer
Summary: This study compared myopic patients with central serous chorioretinopathy (CSC) to emmetropic patients with CSC and myopic, non-CSC patients. It found that myopic CSC presents similar imaging and clinical characteristics as emmetropic CSC, except for thinner choroids. Other imaging characteristics may aid in the diagnostic process considering the structural changes of myopia.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Peripheral Vascular Disease
Anna Rogowska, Lukasz Obrycki, Zbigniew Kulaga, Claudia Kowalewska, Mieczyslaw Litwin
Summary: The study found that hypertensive children show signs of microcirculation remodeling and decreased neural layer of the retina, associated with hypertensive macrocirculation remodeling characterized by increased carotid intima-media thickness and elevated central systolic blood pressure.
Article
Ophthalmology
Noriko Nakao, Tae Igarashi-Yokoi, Hiroyuki Takahashi, Shiqi Xie, Kosei Shinohara, Kyoko Ohno-Matsui
Summary: This study used UWF-OCT images to determine the shape of posterior staphylomas in eyes with pathologic myopia and identified factors contributing to the shape and grade of the staphylomas. Age and axial length were found to be significantly correlated with different types of staphylomas. Quantitative analysis of UWF-OCT images is helpful in determining the shape of staphylomas.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Editorial Material
Ophthalmology
David Cui, Ian J. Saldanha, Gavin Li, Priya M. Mathews, Michael X. Lin, Esen K. Akpek
Summary: This article reports on the heterogeneity in methodology of clinical trials submitted to the US Food and Drug Administration for approval of topical dry eye treatments. Multiple outcome measures were used in these trials, highlighting the need for standardized assessment tools to optimize the evaluation and comparison of therapeutic benefits.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Adanna Udeh, Dana Huh, Terri Young, O'rese Knight, Fasika Woreta
Summary: This study examines the rates and trends of faculty promotions within the field of ophthalmology, with a focus on the rates of promotion among underrepresented in medicine (URiM) faculty. The results show that Black faculty had lower promotion rates and were more likely to leave academic medicine, highlighting the need for strategies and policies to address equity in promotion rates and retention of URiM faculty in academic ophthalmology.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Ursula Greferath, Erica Fletcher, Judy Savige, Heather G. Mack
Summary: Retinal drusen are uncommon in IgA nephropathy, but they resemble drusen found in age-related macular degeneration. The IgA-staining deposits in the drusen are likely related to systemic deposition of IgA. The nature of cystic spaces in the drusen is still unknown. Further research on the retinas of people with glomerulonephritis is recommended.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Andrew Mihalache, Ryan S. Huang, Nikhil S. Patil, Marko M. Popovic, Ashwin Mallipatna, Peter J. Kertes, Rajeev H. Muni, Radha P. Kohly
Summary: This study examines sociodemographic predictors of poor vision in children and adolescents in the US. The findings suggest that factors such as affordability of medical care, public health insurance, age, and parental education level are associated with vision difficulty. Addressing these disparities through public health policies is crucial for achieving equity in vision health.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Johannes Birtel, Richard Caswell, Samantha R. De Silva, Philipp Herrmann, Salwah Rehman, Andrew J. Lotery, Omar A. Mahroo, Michel Michaelides, Andrew R. Webster, Robert E. Maclaren, Peter Charbel Issa
Summary: The study investigated the phenotype, variability, and penetrance of IMPG2-related maculopathy. The results showed that mono-allelic IMPG2 variants could result in haploinsufficiency manifesting as a maculopathy with variable penetrance and expressivity. Family members of patients with IMPG2-related retinitis pigmentosa may also present with vitelliform lesions. The maculopathy is usually limited to the fovea and is associated with moderate visual impairment.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Colas Nils Authie, Mylene Poujade, Alireza Talebi, Alexis Defer, Ariel Zenouda, Cecilia Coen, Saddek Mohand-Said, Philippe Chaumet-Riffaud, Isabelle Audo, Jose-Alain Sahel
Summary: MOST has been validated as a reliable mobility test for measuring the movement ability of patients with vision impairments in both real and virtual environments.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Maria Krisch, Jordan Ueberroth, Neha Gupta, Stephen Merriam, Mark p. Breazzano
Summary: Orbeez-related ocular trauma can lead to severe visual morbidity and various intraocular sequelae. Adolescents may be at higher risk for posterior segment complications. Elevated IOP and hyphema at initial presentation may indicate a need for more aggressive interventions.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Jaron Pruett, Kelly Ruland, Sean Donahue
Summary: The study aimed to validate or refute the hypothesis that infants with birthweight over 750 g and gestational age over 27 weeks, who did not have retinopathy of prematurity (ROP) at 37 weeks, would not develop treatable ROP. The findings of the study supported the termination of examination at 37 weeks in infants meeting these criteria, as the value of continued screening was minimal.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Emily Sun, Jing Tian, Loaah Eltemsah, Divya Srikumaran, Grace Sun, Jessica Chow, Fasika Woreta
Summary: This study aims to evaluate the research productivity of ophthalmology residency applicants and identify differences in productivity based on gender and race. The findings reveal that women have similar or higher research outputs compared to men, while self-identified underrepresented in medicine (URiM) students have lower research outputs in ophthalmology. Therefore, greater mentorship and support for URiM students are needed to promote the recruitment of diverse trainees in ophthalmology programs.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Isaac A. Bernstein, Ann Caroline Fisher, Kuldev Singh, Sophia Y. Wang
Summary: This study aims to investigate the association between visual field loss and frailty in a nationally representative cohort of US adults.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)