Article
Obstetrics & Gynecology
Stephanie L. Pierce, Jennifer D. Peck, Christy Zornes, Elizabeth Standerfer, Rodney K. Edwards
Summary: Prophylactic antibiotics during labor induction in nulliparous women with obesity can decrease the rates of cesarean delivery and puerperal infection. A larger trial is needed to evaluate these differences.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Article
Medicine, General & Internal
Rachel J. Kearns, Martin Shaw, Piotr S. Gromski, Stamatina Iliodromiti, Deborah A. Lawlor, Scott M. Nelson
Summary: This population-based cohort study in Scotland found that labor epidural analgesia was not independently associated with adverse neonatal or childhood development outcomes. Associations with neonatal resuscitation and admission were likely mediated by mode of delivery.
Article
Medicine, General & Internal
Malia S. Q. Murphy, Robin Ducharme, Steven Hawken, Daniel J. Corsi, William Petrcich, Darine El-Chaar, Lise Bisnaire, Daniel I. McIsaac, Deshayne B. Fell, Shi Wu Wen, Mark C. Walker
Summary: This study found that intrapartum epidural analgesia was associated with a small increase in the risk of ASD in offspring. However, the biological plausibility of this association remains unclear, and caution should be exercised when interpreting the findings.
Article
Medicine, General & Internal
Tzuria Peled, Hen Y. Sela, Jordanna Joseph, Tal Martinotti, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Summary: This study aims to investigate the factors associated with failed trial of labor after a cesarean section (TOLAC) in women with twin gestation. The study found that failed TOLAC was associated with assisted reproductive technology, lack of oxytocin use, lack of epidural analgesia, and preterm birth. Further analysis revealed that cervical dilation on admission, no use of oxytocin, gestational age at delivery, and lack of epidural analgesia were significantly associated with failed TOLAC.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Veronica Azmy, Lisbet S. Lundsberg, Jennifer Culhane, Jason Kwah, Caitlin Partridge, Moeun Son
Summary: Pregnant individuals with a documented penicillin allergy have a higher risk of postpartum endometritis and their neonates have a higher risk of having a postnatal hospital stay lasting more than 72 hours. There were no significant differences seen in other maternal and neonatal outcomes between patients labeled with a penicillin allergy and those without. However, pregnant individuals with a penicillin allergy were more likely to receive alternative non-beta lactam antibiotics.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Rania Hassan Mostafa Ahmed, Mohamed Samir Eid Sweed, Gasser Adly El-Bishry, Raghda Khaled Hassan
Summary: This study compared the effectiveness and safety of oxytocin infusion and oral misoprostol for inducing labor in pregnant women with term prelabor membrane rupture. The study showed that both methods were effective and safe, but oral misoprostol resulted in a shorter induction to delivery interval in multiparous women.
REPRODUCTIVE SCIENCES
(2023)
Article
Obstetrics & Gynecology
Ann M. Bruno, Amanda A. Allshouse, Torri D. Metz
Summary: Based on data analysis from 2010 to 2020, the rate of attempted vaginal birth after cesarean (VBAC) increased from 15.3% in 2010 to 21.7% in 2020. The rate of successful trial of labor after cesarean (TOLAC) also increased from 69.8% to 74.7% during this period. By 2020, the VBAC rate reached 16.2%.
OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Stephanie L. Pierce, Courtney M. Bisson, Molly E. Dubois, Sarah B. Grimes, Mikaela S. Katz, Mary M. Weed, Sabrina N. Wyatt, Erin K. Eckart, Jennifer D. Peck, Rodney K. Edwards
Summary: Results of the study suggest that adding azithromycin to standard preoperative antibiotic prophylaxis for cesarean delivery may not significantly decrease infection rates, especially for women who are not in labor.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Review
Obstetrics & Gynecology
Metabel T. Markwei, Ifeoluwa Babatunde, Nityam Rathi, Cong Fan, Marie-Ann Prah, Julia Joo, Loren Hackett, David E. Soper, Oluwatosin Goje
Summary: The study shows that preincision cefazolin with adjunctive prophylaxis can significantly reduce postcesarean delivery surgical site infections and duration of hospital stay compared to cefazolin alone, but does not have a significant effect on maternal febrile morbidity. Future investigations are needed to establish the relative efficacies of different adjunctive antibiotic options.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Maciej W. Socha, Wojciech Flis, Milosz Pietrus, Mateusz Wartega
Summary: Induction of labor is a common procedure in modern obstetrics and its frequency is expected to increase. The study found that the use of Misoprostol for labor induction may lead to more cesarean sections and nonreassuring fetal heart rate patterns. On the other hand, using Dinoprostone or Foley catheter for induction may prolong labor time but with a lower risk of nonreassuring fetal heart rate patterns.
Article
Obstetrics & Gynecology
Amihai Rottenstreich, Gabriel Levin, Abraham Tsur, Daniel Shai, Raanan Meyer
Summary: Nulliparity and onset of fever prior to active labor are the strongest independent predictors of cesarean delivery in women with chorioamnionitis.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Article
Obstetrics & Gynecology
Margo S. Harrison, Ana Garces, Lester Figueroa, Jamie Westcott, Michael Hambidge, Nancy F. Krebs
Summary: This analysis aimed to observe if outcomes of repeat cesarean birth vary by timing among women with a history of one prior cesarean birth in Guatemala. It was found that hypertensive disease increases the likelihood of pre-labor cesarean, while outcomes after failed trial of labor do not appear worse than those after pre-labor cesarean birth.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Stephen E. Gee, Marwan Ma'ayeh, Hannah Cackovic, Philip Samuels, Stephen F. Thung, Mark B. Landon, Kara M. Rood
Summary: A study on using isosorbide mononitrate for labor induction in pregnancies complicated by hypertensive disease did not decrease the rate of cesarean deliveries, showing no significant difference between the isosorbide mononitrate group and the placebo group.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Obstetrics & Gynecology
Bijan Morshedi, Samantha Strohm, Hannah James, Charles Springer, Lindsay Gould, Andrea Thurman, Stacy Slat
Summary: This study suggests that using nonsterile gloves for cervical examinations during labor does not significantly increase the risk of infection, and could result in cost savings of up to 92.4% at the institution.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Editorial Material
Obstetrics & Gynecology
Diogo Ayres-de-Campos
Summary: Healthcare professionals in labor wards worldwide face the challenges of managing an emotionally charged period for women, along with long working hours, sleep deprivation, press scrutiny, and legal disputes. Disagreements among scientific institutions on intrapartum care hinder consistency in patient counseling and teamwork. Clarifying basic concepts, such as admission criteria and intervention thresholds, is crucial for the ease of healthcare professionals' work. The involvement of international and national organizations is important for widespread dissemination of these concepts.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)