Article
Pediatrics
Carrie Townley Flores, Amy Gerstein, Ciaran S. Phibbs, Lee M. Sanders
Summary: The study found that moderate and late preterm birth is associated with increased risks of low performance in mathematics and English language arts, chronic absenteeism, and suspension in young children, with the impact being most significant in late elementary school but diminishing in later grades.
JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, General & Internal
Dvora Kluwgant, Tamar Wainstock, Eyal Sheiner, Gali Pariente
Summary: Placenta previa, multiple gestations, and placental abruption were identified as the strongest risk factors for extreme preterm birth. Risk factors including placental abruption and previa, lack of prenatal care, and recurrent pregnancy loss were observed in sub-populations with multiple gestations, previous PTB, and indicated PTBs. Placental abruption emerged as the most significant risk factor across all groups, with no significant differences observed between sub-populations.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Xi Chen, Xiaoli Zhang, Wenhua Li, Wendong Li, Yong Wang, Shan Zhang, Changlian Zhu
Summary: Preterm births with different etiologies are associated with varying neonatal complications, but no differences in neurodevelopmental outcomes were observed at 12 months of corrected age.
FRONTIERS IN NEUROLOGY
(2021)
Article
Obstetrics & Gynecology
Elise O. R. Kearsey, Jasper Been, Vivienne L. Souter, Sarah J. Stock
Summary: This study examined the impact of the publication of the Antenatal Late Preterm Steroids study on the rates of antenatal corticosteroid therapy administration in late preterm births in the United States. The results showed a significant increase in the rates of antenatal corticosteroid therapy administration in late preterm births and full-term births following the online publication of the study. However, this also resulted in an unnecessary increase in the number of full-term infants receiving antenatal corticosteroid therapy.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Pediatrics
Prachi E. Shah, Julie Poehlmann, Heidi M. Weeks, Maria Spinelli, Blair Richards, Joohee Suh, Niko Kaciroti
Summary: This study investigates the trajectories of late preterm development from infancy to kindergarten reading and math, as well as predictors of academic resilience and risk. The results show that sensitive parenting and preschool attendance are associated with more optimal development trajectories and academic resilience, while suboptimal development and increased academic risk are not related to these factors.
PEDIATRIC RESEARCH
(2023)
Article
Obstetrics & Gynecology
Harriet Aughey, Jennifer Jardine, Hannah Knight, Ipek Gurol-Urganci, Kate Walker, Tina Harris, Jan van der Meulen, Jane Hawdon, Dharmintra Pasupathy
Summary: This cohort study analyzed electronic health records to describe the rates and risk factors associated with iatrogenic and spontaneous preterm birth, as well as the variation in rates between different hospitals. The study found that just over half of all preterm births were iatrogenic and that iatrogenic and spontaneous sub-groups had different maternal demographic and clinical risk factors. There was also more variation between hospitals in rates of iatrogenic preterm births compared to spontaneous preterm births.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Pediatrics
Karolina Sobczyk, Tomasz Holecki, Joanna Wozniak-Holecka, Mateusz Grajek
Summary: In addition to low birth weight and intrauterine growth restriction, prematurity is a major problem in modern neonatology. This study found that there is a relationship between early pregnancy body mass index (BMI) and the risk of preterm delivery, with overweight and obese women being more likely to have extremely and very preterm births.
Article
Physiology
Andrew A. Bremer, Jagteshwar Grewal, Rohan Hazra, Roberto Romero, Diana W. Bianchi
Summary: Premature birth is a major cause of morbidity and mortality, with research efforts focused on prevention and improved treatment for pre-term infants. Collaboration between intramural and extramural research institutions, including multiple institutes and centers at the National Institutes of Health, is crucial in addressing this issue.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2021)
Article
Pediatrics
Brooke Gustafson, Rodney D. Britt Jr, Mariah Eisner, Deepika Narayanan, Mitchell H. Grayson
Summary: This retrospective study identified risk factors associated with the development of wheezing in late preterm infants. Positive family history of asthma, receiving antibiotics during the neonatal period, requiring continuous positive airway pressure for less than 24 hours, and receiving supplemental oxygen during the newborn period were associated with the development of wheezing.
PEDIATRIC PULMONOLOGY
(2023)
Review
Pediatrics
George Daskalakis, Alexandros Psarris, Antonios Koutras, Zacharias Fasoulakis, Ioannis Prokopakis, Antonia Varthaliti, Christina Karasmani, Thomas Ntounis, Ekaterini Domali, Marianna Theodora, Panos Antsaklis, Kalliopi I. Pappa, Angeliki Papapanagiotou
Summary: Preterm birth, a major public health concern worldwide, is the leading cause of neonatal morbidity and mortality. This review analyzes the association between infections and premature birth. Intrauterine infection/inflammation is commonly associated with spontaneous preterm birth. Inflammation-induced overproduction of prostaglandins can lead to uterine contractions and contribute to preterm delivery. Various pathogens, including Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Ureaplasma urealyticum, Mycoplasma hominis, Actinomyces, Candida spp., and Streptococcus spp., have been implicated in premature delivery, chorioamnionitis, and neonatal sepsis. Further research is needed to develop effective preventive methods and reduce neonatal morbidity.
Article
Nutrition & Dietetics
Yu Li, Cheng Chi, Cheng Li, Junyan Song, Zanmin Song, Wenjun Wang, Jing Sun
Summary: Donated breast milk can significantly reduce the incidence of NEC, the duration of parenteral nutrition, and the time of full enteral feeding compared with formula. Adding fortifiers in donated milk could make it as effective as formula in promoting the physical growth of premature infants.
Review
Psychology, Multidisciplinary
Laura Lacalle, Melissa Liher Martinez-Shaw, Yolanda Marin, Yolanda Sanchez-Sandoval
Summary: This systematic review summarized the empirical evidence on prematurity as a risk factor for cognitive development in school-age children. The study included articles published between 2012 and 2022, focusing on the intelligence quotient (IQ) of preterm children aged 6-12 years. The results showed that premature birth was associated with lower IQ scores compared to full-term children, with perinatal and family variables playing a significant role in cognitive development.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Pediatrics
Dustin D. Flannery, Erika M. Edwards, Sarah A. Coggins, Jeffrey D. Horbar, Karen M. Puopolo
Summary: This study examines the epidemiology, microbiology, and outcomes of late-onset sepsis among very preterm infants in the United States. The findings reveal a significant proportion of infants suffering from late-onset sepsis, particularly those born at the lowest gestational ages. Infected infants have higher mortality rates and survivors are at increased risk of technology-dependent chronic morbidities.
Article
Nutrition & Dietetics
Buse Ozer Bekmez, Serife Suna Oguz
Summary: In very preterm babies, adding phosphorus to parenteral nutrition from the first day can reduce the occurrence of hypophosphatemia and hypercalcemia without causing hypernatremia or other complications.
CLINICAL NUTRITION
(2022)
Article
Pediatrics
Kjersti Kvernebo Sunnergren, Ann-Katrine Karlsson, Kerstin Allvin, Staffan Nilsson, Carina Ankarberg-Lindgren, Jovanna Dahlgren
Summary: This study found that adrenal androgen concentrations in boys born moderate to late preterm were correlated with weight and waist-to-height ratios during childhood from 5 to 10 years of age, suggesting that body composition plays a more significant role in adrenal androgen secretion than gestational age and birth size.
Article
Obstetrics & Gynecology
Tracy Caroline Bank, Emily Nuss, Keshab Subedi, Matthew K. Hoffman, Anthony Sciscione
Summary: This study aimed to compare the outcomes of women with isolated maternal fevers treated with antibiotics and expectant management. The results showed a lower rate of postpartum fever in women who received antibiotics, but a higher rate of neonatal intensive care unit admissions and 5-minute Apgar score of <7.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Ramesh Araganji, Manjunath S. Somannavar, Sunil S. Vernekar, Avinash Kavi, Matthew K. Hoffman, Shivaprasad S. Goudar
Summary: The study aimed to determine the impact of low-dose aspirin on markers of maternal inflammation and placental function. Results showed that women who received low-dose aspirin had lower levels of Alpha Feto-Protein (AFP) in early pregnancy compared to those who received a placebo.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Helen B. Gomez Slagle, Yaneve N. Fonge, Richard Caplan, Courtney K. Pfeuti, Anthony C. Sciscione, Matthew K. Hoffman
Summary: Early amniotomy, especially within 1 hour of Foley catheter expulsion, can reduce the duration of labor for individuals undergoing combined misoprostol and Foley catheter labor induction at term.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Critical Care Medicine
Francesca L. Facco, Susan Redline, Shannon M. Hunter, Phyllis C. Zee, William A. Grobman, Robert M. Silver, Judette M. Louis, Grace W. Pien, Brian Mercer, Judith H. Chung, C. Noel Bairey Merz, David M. Haas, Chia-Ling Nhan-Chang, Hyagriv N. Simhan, Frank P. Schubert, Samuel Parry, Uma Reddy, George R. Saade, Matthew K. Hoffman, Lisa D. Levine, Ronald J. Wapner, Janet M. Catov, Corette B. Parker
Summary: There is a link between sleep-disordered breathing (SDB) during pregnancy and/or after delivery with hypertension (HTN) and metabolic syndrome (MS). This study found that an apnea-hypopnea index (AHI) >= 5 during pregnancy was associated with an increased risk of MS, while an oxygen desaturation index (ODI) >= 5 during pregnancy was significantly associated with both HTN and MS. Participants who had persistently elevated AHI and ODI during pregnancy and at 2-7 years after delivery had the highest risk for HTN and MS.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Obstetrics & Gynecology
Amir Lueth, Nathan Blue, Robert M. Silver, Amanda Allshouse, Matthew Hoffman, William A. Grobman, Hyagriv N. Simhan, Uma Reddy, David M. Haas
Summary: This study aimed to characterize risk factors and outcomes for placental abruption in nulliparous women. Results showed that the main risk factors for abruption were gravidity and the likelihood of preterm birth. Neonatal morbidities associated with abruption were primarily due to preterm birth.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Review
Public, Environmental & Occupational Health
Mark A. Klebanoff, Ewoud Schuit, Ronald F. Lamont, Per-Goeran Larsson, Hein J. Odendaal, Austin Ugwumadu, Herbert Kiss, Ljubomir Petricevic, William W. Andrews, Matthew K. Hoffman, Andrew Shennan, Paul T. Seed, Robert L. Goldenberg, Lynda M. Emel, Vinay Bhandaru, Steven Weiner, Michael D. Larsen
Summary: Using individual participant data (IPD), this study investigated whether treatment of bacterial vaginosis (BV) during pregnancy reduced the risk of preterm delivery (PTD). The results showed that clindamycin treatment was beneficial in studies providing IPD, but when data from studies without IPD were imputed, neither metronidazole nor clindamycin treatment reduced the risk of PTD or prolonged pregnancy. The timing of treatment and history of PTD did not affect treatment efficacy.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)
Article
Obstetrics & Gynecology
Avinash Kavi, Matthew K. Hoffman, Manjunath S. Somannavar, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Janet Moore, Eleanor Nielsen, Norman Goco, Elizabeth M. McClure, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Musaku Mwenechanya, Elwyn Chomba, Waldemar A. Carlo, Lester Figueroa, Nancy F. Krebs, Saleem Jessani, Sarah Saleem, Robert L. Goldenberg, Prabirkumar Das, Archana Patel, Patricia L. Hibberd, Fabian Esamai, Sherri Bucher, Marion Koso-Thomas, Robert Silver, Richard J. Derman
Summary: Assessing the impact of low-dose aspirin starting in early pregnancy, it was found that it can delay the occurrence of preterm hypertensive disorders of pregnancy. Compared with the placebo group, women who received aspirin had lower proportions of developing hypertensive disorders of pregnancy before 28 weeks, before 34 weeks, and before 37 weeks. The results of this study suggest that early administration of low-dose aspirin can delay the onset of hypertension.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Meeting Abstract
Obstetrics & Gynecology
Helen B. Gomez Slagle, Anthony C. Sciscione, Matthew Hoffman, Marwan Ma'ayeh
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Ghamar Bitar, Wei Liu, Jade Tunguhan, Kaveeta V. Kumar, Matthew K. Hoffman
Summary: This study developed a predictive algorithm using machine learning to predict all-cause preterm birth based on clinical, demographic, and laboratory data. The results showed that these information can predict preterm birth with moderate precision.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Health Care Sciences & Services
Helen B. Gomez Slagle, Matthew K. Hoffman, Richard Caplan, Philip Shlossman, Anthony C. Sciscione
Summary: The use of text-based screening for type 2 diabetes in the postpartum period has shown comparable accuracy and predictive value to the traditional 2-hour oral glucose tolerance testing. Remote text-based screening can serve as a feasible alternative to in-person screening, leading to increased follow-up rates for diabetes screening.
Article
Obstetrics & Gynecology
Helen B. Gomez Slagle, Matthew K. Hoffman, Yaneve N. Fonge, Richard Caplan, Anthony C. Sciscione
Summary: The study found that the number of cervical exams performed during term labor is associated with an increased risk of developing clinical chorioamnionitis. Therefore, unnecessary cervical exams should be avoided during term labor management.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Meeting Abstract
Obstetrics & Gynecology
C. K. Pfeuti, M. K. Hoffman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Sarah Al-Nafisee, Ronald J. Wapner, Cynthia Gyamfi-Bannerman, Qi Yan, Matthew Hoffman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Tracy Caroline Bank, Kathryn Vollum, Emily Nuss, Ghamar Bitar, Matthew Hoffman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Tracy Caroline Bank, Emily Nuss, Kathryn Vollum, Ghamar Bitar, Matthew Hoffman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
