Article
Cardiac & Cardiovascular Systems
Bryan S. Benn, Cameron G. Gmehlin, Jonathan S. Kurman, John Doan
Summary: Electromagnetic navigation guided bronchoscopy with transbronchial lung cryobiopsy may improve diagnostic yield for small, peripheral lung nodules. In this study, sequential biopsies were performed using transbronchial needle aspiration, forceps biopsy, and cryobiopsy, with cryobiopsy contributing the highest diagnostic yield. The procedure was safe, with no significant complications. Future studies should focus on identifying nodule characteristics and comparing biopsy tools to optimize diagnostic yield and minimize risk.
RESPIRATORY MEDICINE
(2022)
Article
Oncology
Samy Lachkar, Loic Perrot, Diane Gervereau, Marielle De Marchi, Helene Morisse Pradier, Edouard Dantoing, Nicolas Piton, Luc Thiberville, Florian Guisier, Mathieu Salaun
Summary: This study evaluated the standardized procedure of first-line radial-endobronchial ultrasound (r-EBUS) and virtual bronchoscopy planner for the diagnosis of peripheral lung cancer. The results showed that r-EBUS and VB planner can be used as a first-line procedure to assess peripheral lung cancer due to its ease of perform, cost-effectiveness, and efficiency.
Article
Oncology
Fawad Aleem Chaudry, Maureen Thivierge-Southidara, Juan Carlos Molina, Samid M. Farooqui, Syed Talal Hussain, Moishe Libermen
Summary: With the increasing incidence of finding lung nodules since the advent of lung cancer screening, this study compared the diagnostic accuracy and safety profile of two commonly used techniques: Electromagnetic navigational bronchoscopy (ENB) and CT-guided transthoracic needle aspiration (TTNA). The study found that CT-guided TTNA had a higher diagnostic accuracy but also a higher rate of complications compared to ENB.
Review
Oncology
Samuel T. Freyaldenhoven, Hisashi Tsukada
Summary: The diagnosis of small lung lesions by electromagnetic navigational bronchoscopy is less effective compared to CT guided percutaneous transthoracic needle lung biopsy. Robotic bronchoscopy is a promising new technology that may revolutionize the diagnosis of small lung lesions. Real-time tools such as electromagnetic navigation, radial-endobronchial ultrasound, and cone beam CT have the potential to further improve the diagnostic yield rate.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Cameron G. Gmehlin, Jonathan S. Kurman, Bryan S. Benn
Summary: The novel system combining fluoroscopic navigation with digital tomosynthesis and continuous catheter tip tracking provides an overall improved diagnostic accuracy compared to historical controls for guiding lung nodule biopsies, even for small, bronchus sign negative lesions. Future studies are needed to determine the optimal modality for patients with different nodules to provide tailored procedures for each individual lesion's unique characteristics.
RESPIRATORY MEDICINE
(2022)
Article
Medicine, General & Internal
Ju Hyun Oh, Chang-Min Choi, Seulgi Kim, Se Jin Jang, Sang Young Oh, Mi Young Kim, Hee Sang Hwang, Wonjun Ji
Summary: ENB-guided biopsy showed a high success rate and good accuracy in obtaining tissue samples for molecular testing in patients with peripheral lung lesions. Despite one case failing to reach the target lesion, the overall diagnostic accuracy was 68.0%. Molecular testing was successfully performed in 92.3% of patients diagnosed with NSCLC.
Article
Medicine, General & Internal
Ju Yeun Song, Sun Hye Shin, Hongseok Yoo, Byeong-Ho Jeong, Sang-Won Um, Hojoong Kim, O. Jung Kwon, Kyungjong Lee
Summary: Combining ENB-TBLB/TBNA with R-EBUS-TBLB improves sensitivity and diagnostic accuracy for lung nodules.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Micah Z. Levine, Sam Goodman, Robert J. Lentz, Fabien Maldonado, Otis B. Rickman, James Katsis
Summary: Interventional pulmonology has evolved from a niche subspecialty to a standard component in advanced medical centers, with a focus on diagnosing and treating pulmonary nodules. Distinguishing benign from malignant nodules can be clinically challenging, but accurate differentiation is crucial for patients and the healthcare system as a whole.
Article
Respiratory System
Chang-Hao Zhong, Zhu-Quan Su, Wei-Zhan Luo, Wan-Yuan Rao, Jia-Xin Feng, Chun-Li Tang, Yu Chen, Xiao-Bo Chen, Ming-Yue Fan, Shi-Yue Li
Summary: The study demonstrates that hierarchical clock-scale hand-drawn mapping can serve as a feasible and economical method for guiding peripheral pulmonary nodule biopsy. Compared with virtual bronchoscopic navigation, this method provides a comparable diagnostic yield and requires less planning pathway time, total operation time, and operating cost.
RESPIRATORY RESEARCH
(2022)
Article
Critical Care Medicine
Tejaswi R. Nadig, Nina Thomas, Paul J. Nietert, Jessica Lozier, Nichole T. Tanner, Jessica S. Wang Memoli, Nicholas J. Pastis, Gerard A. Silvestri
Summary: A systematic review found that the diagnostic yield of guided bronchoscopy in diagnosing peripheral pulmonary lesions (PPLs) has not improved over the past decade, and there is no significant difference in yield between different technologies. However, larger lesion size, presence of bronchus sign, and higher malignancy prevalence in the study population were associated with a higher diagnostic yield.
Article
Oncology
Barak Pertzov, Evgeni Gershman, Shimon Izhakian, Moshe Heching, Shai Moshe Amor, Dror Rosengarten, Mordechai Reuven Kramer
Summary: This study evaluated the diagnostic yield and safety among patients undergoing peripheral pulmonary nodule biopsy with the LungVision system. The system showed good feasibility and safety, with a diagnostic yield of 81.8% overall and 72.2% for lesions smaller than 20 mm. Cryobiopsy with the system showed added diagnostic value, with malignant cells detected in tissue that was not found with other sampling tools. No major complications were reported, except for one patient who required chest tube treatment for pneumothorax.
Review
Respiratory System
Satish Kalanjeri, Anna Abbasi, Munish Luthra, Jeremy C. Johnson
Summary: This review discusses various invasive diagnostic modalities for lung nodules, including CT-guided lung nodule biopsy and bronchoscopy. While CT-guided biopsy has a high diagnostic yield, it comes with the risk of pneumothorax; bronchoscopy is safer but less diagnostically effective. Emerging technologies like cone-beam CT scan and robotic bronchoscopy show promise in improving diagnostic yield.
EXPERT REVIEW OF RESPIRATORY MEDICINE
(2021)
Article
Oncology
Yichen Zhang, Michael J. Simoff, David Ost, Oliver J. Wagner, James Lavin, Beth Nauman, Mei-Chin Hsieh, Xiao-Cheng Wu, Brian Pettiford, Lizheng Shi
Summary: This research analyzed the clinical pathway and characteristics of patients with lung cancer and solitary pulmonary nodules (SPN). The study found that the majority of lung cancer patients were in stages III or IV, and some SPN patients did not receive diagnostic work-up.
Review
Respiratory System
Jennifer D. D. Duke, Janani Reisenauer
Summary: Robotic bronchoscopy has advanced the detection and diagnosis of pulmonary nodules by providing improved navigation and maneuverability. This review highlights the technological advancements and future directions in the field of interventional pulmonary for the treatment of lung cancer through robotic bronchoscopy.
EXPERT REVIEW OF RESPIRATORY MEDICINE
(2023)
Article
Oncology
Jiabi Zhao, Lin Sun, Ke Sun, Tingting Wang, Bin Wang, Yang Yang, Chunyan Wu, Xiwen Sun
Summary: By establishing a radiomics nomogram model based on CT scans, combined with clinical characteristics and imaging features, pulmonary cryptococcosis and lung adenocarcinoma can be effectively distinguished, providing significant clinical benefits in the diagnosis of solitary pulmonary solid nodules.
FRONTIERS IN ONCOLOGY
(2021)