Review
Endocrinology & Metabolism
Jordan C. Barone, Mitchell P. Butler, Ashley Ross, Anna Patterson, Melissa Wagner-Schuman, Tory A. Eisenlohr-Moul
Summary: Cyclic hormonal variations during the menstrual cycle contribute to multiple central nervous system disorders, such as premenstrual mood disorder, menstrual migraine, and catamenial epilepsy. However, these fields have operated independently without systematic communication. This scoping review examines existing research studies in these disorders to outline hormonal manipulation trials and identify gaps in the literature. Despite the heterogeneity of treatments and study designs, there is significant overlap in the neuroendocrine-based hormone sensitivity among these menstrual cycle-related disorders.
FRONTIERS IN NEUROENDOCRINOLOGY
(2023)
Article
Psychology, Clinical
Sibel Nayman, Theresa Beddig, Iris Reinhard, Christine Kuehner
Summary: In women with premenstrual dysphoric disorder (PMDD), habitual mindfulness and reappraisal have a positive effect on momentary mood, but do not protect against premenstrual mood deterioration. Additionally, habitual mindfulness seems to buffer blunted cortisol activity in women with PMDD, especially during the menstrual phase.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Tory Eisenlohr-Moul, Madeline Divine, Katja Schmalenberger, Laura Murphy, Brett Buchert, Melissa Wagner-Schuman, Alyssa Kania, Sabina Raja, Adam Bryant Miller, Jordan Barone, Jaclyn Ross
Summary: This study found high rates of self-injurious thoughts and behaviors in individuals reporting a diagnosis of PMDD, emphasizing the need for further research on understanding and preventing STBs in PMDD. Clinical practice guidelines for PMDD should address comorbidities and include frequent screenings for suicide risk. STBs should be considered for inclusion in future updates of the DSM PMDD diagnostic criteria.
Article
Clinical Neurology
Christophe Moderie, Philippe Boudreau, Ari Shechter, Paul Lesperance, Diane B. Boivin
Summary: The study found that intervention with exogenous melatonin increased urinary aMt6, reduced sleep onset latency, decreased slow-wave sleep, increased Stage 2 sleep, and improved symptoms in PMDD patients. Circadian parameters derived from 24-hour plasma melatonin and CBT did not differ significantly between intervention and baseline conditions, except for an increased melatonin mesor in the intervention condition. Ovarian hormones remained comparable between the two conditions.
Article
Clinical Neurology
Christophe Moderie, Philippe Boudreau, Ari Shechter, Paul Lesperance, Diane B. Boivin
Summary: The study suggests that exogenous melatonin can increase urinary melatonin levels, reduce sleep onset latency, decrease slow-wave sleep, and increase stage 2 sleep in women with premenstrual dysphoric disorder (PMDD). Additionally, melatonin intervention improves mood and symptoms in these patients.
Article
Nutrition & Dietetics
Cielo Garcia-Montero, Miguel A. Ortega, Miguel Angel Alvarez-Mon, Oscar Fraile-Martinez, Adoracion Romero-Bazan, Guillermo Lahera, Jose Manuel Montes-Rodriguez, Rosa M. Molina-Ruiz, Fernando Mora, Roberto Rodriguez-Jimenez, Javier Quintero, Melchor Alvarez-Mon
Summary: This article explores the role of malnutrition in the onset and course of major depressive disorder (MDD) in women. Women are twice as likely to suffer from MDD compared to men, which is related to fluctuations in sexual hormones and dietary habits and nutritional requirements during specific life periods. Nutritional intervention programs with a gender perspective may potentially improve women's mental health and quality of life.
Review
Psychiatry
Bethany Sander, Jennifer L. Gordon
Summary: Recent findings suggest that early menopause transition may exacerbate existing MRMDs due to hormonal changes, leading to depressive mood in some women. There is also evidence that some women with MRMD may have increased mood sensitivity to ovarian hormone withdrawal during late menopause transition and early postmenopausal phase. Further research is needed to clarify the trajectory of premenstrual dysphoria in the menopause transition and to be vigilant for potential worsening of symptoms in perimenopause for women with past or current premenstrual dysphoric disorder.
CURRENT PSYCHIATRY REPORTS
(2021)
Article
Psychiatry
Aysenur Turan, Iffet Guler Kaya, Hilal Basak Cakir, Secil Topaloglu
Summary: This study investigated the prevalence and correlates of PMS and PMDD in 1125 female college students aged 18-25. The findings showed that approximately 49.2% of participants had PMS and 48.0% had PMDD. Blood type B, lack of physical activity, longer menstrual cycle duration, and higher caffeine intake were associated with PMS and PMDD.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE
(2023)
Article
Psychiatry
Yola El Dahr, Taiane de Azevedo Cardoso, Sabrina K. Syan, Luisa Caropreso, Luciano Minuzzi, Mara Smith, Olivia R. Allega, Maha El-Tayebani, Jeronimo Mendes-Ribeiro, Luciano Dias de Mattos Souza, Ricardo Azevedo da Silva, Thaise Campos Mondin, Fernanda Pedrotti Moreira, Flavio Kapczinski, Karen Jansen, Benicio N. Frey
Summary: We investigated whether women diagnosed with comorbid bipolar disorder and premenstrual dysphoric disorder experience higher disruptions in biological rhythms. Two independent study samples were used. The results showed that all diagnostic groups had greater disruptions in biological rhythms compared to controls. Women with bipolar disorder experienced greater disruption in overall biological rhythms and in sleep, activity, and eating patterns compared to those with premenstrual dysphoric disorder. These findings suggest that the comorbidity between bipolar disorder and premenstrual dysphoric disorder may have a significant impact on biological rhythms.
ARCHIVES OF WOMENS MENTAL HEALTH
(2022)
Article
Clinical Neurology
Yuncheng Zhu, Xiaohui Wu, Hongmei Liu, Zhiang Niu, Jie Zhao, Fan Wang, Ruizhi Mao, Xiaoyun Guo, Chen Zhang, Zuowei Wang, Jun Chen, Yiru Fang
Summary: This study suggests the value of the Decision Tree models, using biochemical parameters as diagnostic predictors for BD and MDD. Backward stepwise multivariate regression analysis and CHAID segmentation analysis were used to determine the discrimination between BD and MDD. In the male patient model, DBIL was the first splitting variable, with LDH and IBIL as the second; in the female patient model, DBIL was also the first splitting variable, with UA, LDH, and IBIL as the second.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Ju-Yu Yen, Pai-Cheng Lin, Ching-Jung Hsu, Chi Lin, I-Ju Chen, Chih-Hung Ko
Summary: This study investigated cognitive function in women with premenstrual dysphoric disorder (PMDD) and found that attention and response inhibition were impaired in the late luteal phase. Additionally, associations were observed between cognitive functions and impulsivity, decision-making style, and irritability. These results reveal the different courses in different domains of cognitive impairment in PMDD.
ARCHIVES OF WOMENS MENTAL HEALTH
(2023)
Article
Psychiatry
Dian-Jeng Li, Shih-Jen Tsai, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang, Mu-Hong Chen
Summary: This study aimed to investigate the association between a history of premenstrual dysphoric disorder (PMDD) and the subsequent risk of major affective disorders. The results showed that women with PMDD had a higher risk of developing unipolar depression and bipolar disorder compared to those without PMDD.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Behavioral Sciences
Liisa Hantsoo, Jennifer L. Payne
Summary: Premenstrual dysphoric disorder (PMDD) is a severe mood disorder that is associated with hormonal fluctuations, and its underlying biology is not yet fully understood. Recent research suggests that abnormal central nervous system response to neuroactive steroid hormone fluctuations, alterations in serotonergic and GABA transmission, genetic heritability, and cellular vulnerability to sex hormones may contribute to PMDD. However, the findings have not yet been integrated into a complete description of PMDD's underlying biology, and a subtyping approach may be beneficial for future research.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Neurosciences
Inbal Reuveni, Rotem Dan, Laura Canetti, Atira S. Bick, Ronen Segman, Moria Azoulay, Carmel Kalla, Omer Bonne, Gadi Goelman
Summary: Premenstrual dysphoric disorder (PMDD) in women is associated with abnormal brain network connectivity, specifically decreased default mode network connectivity, increased salience network connectivity, and decreased central executive network connectivity.
BIOLOGICAL PSYCHIATRY
(2023)
Article
Computer Science, Cybernetics
Soyoung Ahn, Yongsoon Choi
Summary: This study developed a smart mirror called Smiley, which can only be seen when users smile, and evaluated its effects on women suffering from PMS. The results showed that smiling can change negative emotions caused by PMS and positively influence users' psychological stability and daily life.
INTERNATIONAL JOURNAL OF HUMAN-COMPUTER INTERACTION
(2023)