Article
Neurosciences
Alberto Fernandez-Pena, Francisco J. Navas-Sanchez, Daniel Martin de Blas, Luis Marcos-Vidal, Manuel Desco, Susanna Carmona
Summary: Surgical menopause causes cortical atrophy, while parity may mitigate the impact.
HUMAN BRAIN MAPPING
(2023)
Article
Obstetrics & Gynecology
Micaela Sundell, Jan Brynhildsen, Mats Fredrikson, Mikael Hoffmann, Anna-Clara Spetz Holm
Summary: This retrospective cohort study in Sweden investigated the use of menopausal hormone therapy (MHT) in premenopausal women after bilateral oophorectomy. The study found that only 69% of women without malignancy underwent MHT within 1 year after surgery, and the duration of treatment was limited. The authors suggest further research is needed to understand the reasons behind the low dispensation rate in this group and improve adherence to treatment guidelines.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Mary Kathryn, Tamandra Morgan, Alisha Othieno, Anne Angeles, Mindy Goldman
Summary: Survival rates of breast cancer patients have been increasing since the 1990s, highlighting the importance of addressing quality of life and gynecologic concerns. Breast cancer diagnosis and treatment uniquely impact women's health issues such as contraception, pregnancy, menopause, and sexual functioning. Hormone-sensitive breast cancer accounts for two-thirds of cases, and adjuvant hormonal therapies have significantly reduced disease recurrence and contralateral breast cancer risk. However, these therapies can lead to menopausal and sexual side effects, requiring healthcare providers to be knowledgeable about safe and effective treatment options.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Natalie Scime, Hilary K. Brown, Alison K. Shea, Erin A. Brennand
Summary: The study investigates the association between past infertility and the type and timing of menopause in midlife women. The results show that women with a history of infertility are more likely to experience surgical menopause and have an elevated risk of earlier surgical menopause until age 43, but there are no differences in the timing of natural menopause.
HUMAN REPRODUCTION
(2023)
Article
Medicine, General & Internal
Ching-Hsiang Chiang, Weishan Chen, I-Ju Tsai, Chung Y. Hsu, Jen-Hung Wang, Shinn-Zong Lin, Dah-Ching Ding
Summary: The study found that hysterectomy may increase the incidence of diabetes mellitus in East Asian women, but adding oophorectomy does not increase the risk. For women aged 30 to 49, undergoing hysterectomy may raise the risk of diabetes.
Article
Medicine, General & Internal
Duo Qian, Zu-feng Wang, Yi-chun Cheng, Ran Luo, Shu-wang Ge, Gang Xu
Summary: Both early natural and surgical menopause are associated with an increased risk of CKD. Early surgical menopause is a hazard factor for survival in the non-CKD group, but not in the CKD group. Further research is required to understand the mechanisms.
FRONTIERS IN MEDICINE
(2022)
Article
Geriatrics & Gerontology
Walter A. Rocca, Liliana Gazzuola Rocca, Carin Y. Smith, Ekta Kapoor, Stephanie S. Faubion, Elizabeth A. Stewart
Summary: This study aimed to investigate the prevalence and types of premature and early menopause in a geographically-defined American population. The results showed that the overall frequency of premature menopause was around 3%, with bilateral oophorectomy being the most common cause.
Article
Geriatrics & Gerontology
A. Gosset, M. Susini, F. Vidal, Y. Tanguy-Le-Gac, E. Chantalat, L. Genre, F. Tremollieres
Summary: This study evaluated the quality of life and associated factors among women who underwent bilateral oophorectomy for the treatment of deep infiltrating endometriosis before the age of 45. The results showed that although oophorectomy can relieve pain in severe DIE, premature menopause is associated with poor quality of life.
Review
Obstetrics & Gynecology
Ouma C. Pillay, Isaac Manyonda
Summary: Surgical menopause, caused by the removal of both ovaries before natural menopause, can lead to premature ovarian insufficiency in women before the age of 40. Hormone replacement therapy should be considered for women who have undergone bilateral salpingo-oophorectomy, with attention to androgen therapy for sexual function and desire.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2022)
Article
Neurosciences
Alana Brown, Nicole J. Gervais, Jenny Rieck, Anne Almey, Laura Gravelsins, Rebekah Reuben, Laurice Karkaby, M. Natasha Rajah, Cheryl Grady, Gillian Einstein
Summary: Women who undergo early bilateral salpingo-oophorectomy (BSO) have a higher risk of developing Alzheimer's disease (AD) compared to women who go through natural menopause. This study investigated the changes in associative memory in young women with BSO and whether these changes were similar to those observed in women with natural menopause. The results suggest that women with BSO without estrogen replacement therapy have similar brain function to women with natural menopause, indicating that early estrogen loss may lead to altered brain function and increased AD risk.
MOLECULAR NEUROBIOLOGY
(2023)
Article
Geriatrics & Gerontology
Ekta Kapoor, Stephanie S. Faubion, Liliana Gazzuola Rocca, Michelle M. Mielke, Carin Y. Smith, Walter A. Rocca
Summary: The study aimed to investigate the trajectories of metabolic parameters after bilateral oophorectomy. The results showed significant differences in weight, body mass index (BMI), and high-density lipoprotein cholesterol (HDL-C) among the three groups. Although there were baseline differences, the changes primarily occurred in the initial 4-5 years. Women who received estrogen therapy after bilateral oophorectomy had similar weight and BMI trends as the control group and experienced an increase in HDL-C over time.
Article
Oncology
Katrina M. Moss, Gita D. Mishra, Efrosinia O. Krejany, Martha Hickey
Summary: This study aimed to understand the clustering of symptoms after premenopausal risk-reducing salpingo-oophorectomy (RRSO), the changes in symptoms over time, and the effects of hormone therapy (HT). Three symptom profiles were identified: Most Symptoms, Few Symptoms, and Sexual Symptoms. Most non-HT users remained highly symptomatic with little chance of improvement by 12 months, while HT users had fewer symptoms and a higher chance of improvement.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Obstetrics & Gynecology
Yukio Suzuki, Yongmei Huang, Alexander Melamed, Caryn M. St Clair, June Y. Hou, Fady Khoury-Collado, Allison Gockley, Melissa Accordino, Dawn L. Hershman, Jason D. Wright
Summary: This study aimed to examine the use of estrogen therapy and patterns of follow-up evaluation in premenopausal women who underwent bilateral salpingo-oophorectomy for benign gynecologic diseases. The study found a substantial decline in estrogen therapy use over the past decade.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Ana-Maria Iancu, Ally Murji, Ovina Chow, Jodi Shapiro, Amanda Cipolla, Lindsay Shirreff
Summary: This study retrospectively reviewed hysterectomies conducted in Ontario, Canada from 2016 to 2019 to evaluate the proportion of justified BSO and determine the prevalence of avoidable BSO. The findings showed that most BSOs were justified based on pathologic diagnosis, with endometrial cancer being the most common indication. However, 5.6% of BSOs were considered avoidable, highlighting the need for standardized practice in BSO.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2022)
Article
Obstetrics & Gynecology
Jellena Wong, Ally Murji, Zahra Sunderji, Ovina Chow, Jodi Shapiro, Wendy Wolfman, Lindsay Shirreff
Summary: This study aimed to examine predictors of concurrent bilateral salpingo-oophorectomy at hysterectomy and found that in some cases, this procedure may not be necessary, with 8% of patients potentially being able to preserve their ovaries. Procedures performed by fellowship-trained surgeons were more likely to have preoperative indications.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2021)
