Article
Oncology
Lucas W. Thornblade, Ernest Han, Yuman Fong
Summary: Patients with colorectal cancer ovarian metastasis have favorable long-term survival. Survival rates are higher if the tumor is isolated to the ovary or if metachronous to the primary cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Oncology
Fangwen Zou, Xuemei Wang, Isabella C. Glitza, Jennifer L. McQuade, Jennifer Wang, Hao Chi Zhang, John A. Thompson, Anusha S. Thomas, Yinghong Wang
Summary: This study demonstrated that fecal calprotectin (FC) concentration can serve as a non-invasive biomarker to predict endoscopic and histologic remission in patients with immune-mediated diarrhea and colitis (IMDC). High FC concentrations were associated with endoscopic inflammation. FC concentrations decreased during the course of treatment in patients.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
Article
Biochemistry & Molecular Biology
Xin-Yu Li, Chuan Liu, Fang-Hua Liu, Gang Zheng, Hui-Juan Yang, Yi-Fan Wei, Xue Qin, Qian Xiao, Yu-Hong Zhao, Song Gao, Ting-Ting Gong, Qi-Jun Wu
Summary: This study investigated the relationship between diet quality and survival in patients with ovarian cancer using Chinese diet quality scores. The results showed that the Chinese Healthy Eating Index was associated with improved overall survival, while the Dietary Balance Index and Chinese Food Pagoda Score were not related to survival.
Article
Oncology
Bong Kyung Bae, Won Kyung Cho, Jeong-Won Lee, Tae-Joong Kim, Chel Hun Choi, Yoo-Young Lee, Won Park
Summary: This study reported the clinical outcomes of salvage radiotherapy for recurrent ovarian cancer and identified predictors of the outcomes. Salvage radiotherapy achieved local control and improved chemotherapy-free survival in carefully selected patients. Pre-radiotherapy platinum resistance and pre-radiotherapy CA-125 doubling time may help with patient selection.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2023)
Article
Oncology
Tianyi Wang, Danielle E. Jake-Schoffman, Mary K. Townsend, Christine Vinci, Walter C. Willett, Shelley S. Tworoger
Summary: Overall, there is not clear evidence to suggest a relationship between early life physical activity and risk of ovarian cancer during adulthood.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Sport Sciences
Morgan J. Farley, David B. Bartlett, Tina L. Skinner, Mia A. Schaumberg, David G. Jenkins
Summary: Exercise has been proven to improve physical and psychosocial well-being for cancer patients. The relationship between exercise and cancer outcomes is believed to be due to the release of anti-inflammatory myokines from skeletal muscle tissue. One important myokine, Interleukin-15 (IL-15), plays a key role in the immune response to cancer by supporting the growth and maturation of T cells and NK cells. Research is needed to better understand how exercise-induced increases in IL-15 can benefit cancer patients.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Oncology
Katrine Dam Olesen, Anja Tolstrup Raedkjaer Larsen, Lars Henrik Jensen, Karina Dahl Steffensen, Stine Rauff Sondergaard
Summary: A retrospective study conducted at Lillebaelt Hospital, University Hospital of Southern Denmark, revealed that treosulfan is a viable treatment option for end-stage ovarian cancer patients with limited treatment alternatives, showing response rates of approximately 15% and generally good tolerability.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Medicine, General & Internal
Lauren M. Hurwitz, Penelope M. Webb, Susan J. Jordan, Jennifer A. Doherty, Holly R. Harris, Marc T. Goodman, Yurii B. Shvetsov, Francesmary Modugno, Kirsten B. Moysich, Joellen M. Schildkraut, Andrew Berchuck, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Susan J. Ramus, Anna H. Wu, Celeste Leigh Pearce, Nicolas Wentzensen, Shelley S. Tworoger, Paul D. P. Pharoah, Britton Trabert
Summary: Frequent aspirin use is associated with reduced ovarian cancer risk, and genetic factors do not appear to modify this association according to a study. The findings suggest that aspirin use may be effective in preventing ovarian cancer regardless of genetic susceptibility.
Article
Medicine, General & Internal
Lauren M. Hurwitz, Penelope M. Webb, Susan J. Jordan, Jennifer A. Doherty, Holly R. Harris, Marc T. Goodman, Yurii B. Shvetsov, Francesmary Modugno, Kirsten B. Moysich, Joellen M. Schildkraut, Andrew Berchuck, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Susan J. Ramus, Anna H. Wu, Celeste Leigh Pearce, Nicolas Wentzensen, Shelley S. Tworoger, Paul D. P. Pharoah, Britton Trabert
Summary: This study suggests that genetic susceptibility to ovarian cancer based on currently identified common genetic variants does not appear to modify the protective association between frequent aspirin use and ovarian cancer risk.
Article
Genetics & Heredity
Amy Finch, Kelly Metcalfe, Mohammad Akbari, Eitan Friedman, Nadine Tung, Barry Rosen, Andrea Eisen, Beth Karlan, William Foulkes, Susan L. Neuhausen, Leigha Senter, Wendy McKinnon, Christine Elser, Ping Sun, Steven A. Narod
Summary: Approximately 1% of the Ashkenazi Jewish population carries the BRCA2 6174delT pathogenic variant, which is associated with the risks of breast and ovarian cancer. Women carrying the 6174delT variant have a significantly lower annual risk for developing breast cancer compared to those carrying other variants in the BRCA2 gene, but the difference in ovarian or fallopian tube cancer risk is not significant.
Article
Public, Environmental & Occupational Health
Tianyi Wang, Mary K. Townsend, Christine Vinci, Danielle E. Jake-Schoffman, Shelley S. Tworoger
Summary: Exposure to parental tobacco smoke in the home, rather than early initiation of smoking, was associated with a modest elevated risk of ovarian cancer. Further investigations are required to confirm these findings and elucidate underlying mechanisms.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Surgery
Hoon Choi, Wonjung Hwang
Summary: Surgical resection is the main treatment for solid tumors, but cancer recurrence after surgery is common. Maintaining anti-tumor cell activity and proper levels of inflammatory mediators are crucial for preventing recurrence. Surgery itself and perioperative interventions can affect these physiological responses.
FRONTIERS IN SURGERY
(2022)
Article
Biochemistry & Molecular Biology
Hiroshi Maruoka, Tomohito Tanaka, Hikaru Murakami, Hiromitsu Tsuchihashi, Akihiko Toji, Misa Nunode, Atsushi Daimon, Shunsuke Miyamoto, Ruri Nishie, Shoko Ueda, Sousuke Hashida, Shinichi Terada, Hiromi Konishi, Yuhei Kogata, Kohei Taniguchi, Kazumasa Komura, Masahide Ohmichi
Summary: This study identified cancer-specific miRNAs in tissue-exudative extracellular vesicles (Te-EVs) of ovarian clear cell carcinomas (OCCs). The levels of these miRNAs were significantly decreased in postoperative serum samples, indicating their potential as biomarkers for the early diagnosis and detection of OCC.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Joseph DeMari, Monica Hagan Vetter, Shruthi Chandra, John L. Hays, Ritu Salani
Summary: The study aimed to investigate practice patterns for surveillance of primary ovarian cancer after complete response to therapy, and to identify the percentage of clinicians who follow the surveillance guidelines endorsed by the Society of Gynecologic Oncology. Results showed that 78% of patients complied with the guidelines, but patients with early-stage cancer and non-serous histologies were more likely to be non-compliant.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Review
Oncology
Eli M. M. Soyfer, Angela G. G. Fleischman
Summary: Myeloproliferative Neoplasm (MPN) is a type of chronic blood cancer derived from a mutated hematopoietic stem cell clone with activated myeloid cytokine receptor signaling. MPN shares similarities with chronic non-cancerous inflammatory conditions in terms of chronicity, symptoms, immune system involvement, environmental triggers, and treatments. Despite being classified as a cancer, MPN behaves more like a chronic inflammatory disease, suggesting it should be positioned in a fluid/spectrum between auto-inflammatory disease and cancer.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medicine, Research & Experimental
Hilde Haugedal Nordal, Magne K. Fagerhol, Anne-Kristine Halse, Hilde Berner Hammer
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
(2018)
Article
Peripheral Vascular Disease
Kristin Angel, Sella A. Provan, Magne K. Fagerhol, Petter Mowinckel, Tore K. Kvien, Dan Atar
AMERICAN JOURNAL OF HYPERTENSION
(2012)
Article
Orthopedics
Hilde Haugedal Nordal, Johan G. Brun, Anne-Kristine Halse, Roland Jonsson, Magne K. Fagerhol, Hilde Berner Hammer
BMC MUSCULOSKELETAL DISORDERS
(2014)
Article
Immunology
Pal Berg-Hansen, Bodvar Vandvik, Magne Fagerhol, Trygve Holmoy
JOURNAL OF NEUROIMMUNOLOGY
(2009)
Article
Multidisciplinary Sciences
Samuel A. Curran, Ivana Hollan, Clett Erridge, David F. Lappin, Colin A. Murray, Gunnar Sturfelt, Knut Mikkelsen, Oystein T. Forre, Sven M. Almdahl, Magne K. Fagerhol, Carl S. Goodyear, Marcello P. Riggio
Article
Medicine, Research & Experimental
Magne K. Fagerhol, Annette Larsen, Johan G. Brun, Hilde B. Hammer, Kristin Angel, Tore K. Kvien, Ingebjorg Kinne, Tor M. Madland
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
(2012)
Letter
Rheumatology
H. H. Nordal, J. G. Brun, A-K Halse, T. M. Madland, M. K. Fagerhol, R. Jonsson
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
(2014)
Article
Rheumatology
Hilde Berner Hammer, Magne K. Fagerhol, Tale Norbye Wien, Tore K. Kvien
ARTHRITIS RESEARCH & THERAPY
(2011)
Article
Immunology
Magne Kristoffer Fagerhol, Egil Johnson, Jon-Magnus Tangen, Ivana Hollan, Mohammad Reza Mirlashari, Lise Sofie Haug Nissen-Meyer, Geir Hetland
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
(2020)
Article
Immunology
Geir Hetland, Magne Kristoffer Fagerhol, Markus Karl Hermann Wiedmann, Arne Vasli Lund Soraas, Mohammad Reza Mirlashari, Lise Sofie Haug Nissen-Meyer, Mette Stausland Istre, Pal Andre Holme, Nina Haagenrud Schultz
Summary: This study investigates prognostic factors for the severity of complications associated with ChAdOx1 vaccination. The levels of H3-NETs and calprotectin were significantly increased in VITT patients and correlated with the severity of vaccination side effects. These inflammatory markers may be used as confirmatory tests in diagnosing VITT.
Article
Rheumatology
Hilde Berner Hammer, Sigrid Odegard, Magne K. Fagerhol, Robert Landewe, Desiree van der Heijde, Till Uhlig, Petter Mowinckel, Tore K. Kvien
ANNALS OF THE RHEUMATIC DISEASES
(2007)
Article
Immunology
A. Larsen, I. B. Bronstein, O. Dahl, T. Wentzel-Larsen, E. K. Kristoffersen, M. K. Fagerhol
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
(2007)
Article
Neurosciences
Russell Foster, Apsara Kandanearatchi, Claire Beasley, Williams Brenda, Nadeem Khan, Magne K. Fagerhol, Ian P. Everall
EUROPEAN JOURNAL OF NEUROSCIENCE
(2006)
Article
Oncology
Annette Larsen, Benedikte Bjorge, Beate Klementsen, Lars Helgeland, Tore Wentzel-Larsen, Magne K. Fagerhol, Nils Hovdenak, Olav Dahl
