Article
Multidisciplinary Sciences
Dana A. Muin, Martina Kollmann, Jasmin Blatterer, Gregor Hoermann, Peter W. Husslein, Ingrid Lafer, Erwin Petek, Thomas Schwarzbraun
Summary: Investigating cardio-pathogenic variants in singleton fetuses after unexplained intrauterine fetal death revealed that most male fetuses died at a median gestational age of 34 weeks, with a high proportion of variants of uncertain significance in cardio-specific genes.
SCIENTIFIC REPORTS
(2021)
Article
Obstetrics & Gynecology
Inmaculada Duyos, Polan Ordas, Beatriz Herrero, Roberto Rodriguez, Miguel Jesus Cabrero, Amelia Fernandez-Zubillaga, Jesus Benito Diez Sebastian, Maria De La Calle, Jose Luis Bartha, Eugenia Antolin
Summary: This study aimed to evaluate the perinatal outcome of monochorionic twins with single intrauterine fetal death, both spontaneous and after fetal therapy, and to assess the antenatal events that increase the risk of cerebral injury. The study found that the risk of cerebral damage is higher in cases of spontaneous intrauterine fetal death, and gestational age at death, selective intrauterine growth restriction, and anemia of the surviving co-twin are the main predictors for prenatal lesions. The overall perinatal survival rate was 88.3% and abnormal neurological outcomes were related to extreme prematurity.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Obstetrics & Gynecology
Pelle G. Lindqvist, Mika Gissler, Birgitta Essen
Summary: Sweden and Finland have a high proportion of low plasma vitamin D levels. National vitamin D fortification was associated with a 15% drop in stillbirths. This finding could be a milestone in preventing stillbirths and reducing health inequalities.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Medicine, General & Internal
Anxia Xie, Yan Cui, Gang Luo, Xianxia Chen, Xuecheng Zhang, Jie Han, Li Tong, Yanming Ren, Xiaoxing Wei
Summary: This study systematically evaluated the cause of fetal death in a Han Chinese woman with monochorionic twinning following in vitro fertilization/embryo transfer. Discrepant karyotypes were discovered between the twins, with one fetus having an abnormal male karyotype (46, XY) and duplication (9) (p24.3-q13), and the other having a normal female karyotype (46, XX). The male fetus was considered to have died due to chromosome 9 aberration, while the female fetus died due to subsequent acute exsanguination through vascular anastomosis. This study highlights the importance of recognizing monochorionic dizygotic twinning and the challenges of clinical management for twins following IVF/double embryo transfer.
FRONTIERS IN MEDICINE
(2023)
Article
Immunology
Lydia L. Shook, Sara Brigida, James Regan, James P. Flynn, Abbas Mohammadi, Behzad Etemad, Molly R. Siegel, Mark A. Clapp, Jonathan Z. Li, Drucilla J. Roberts, Andrea G. Edlow
Summary: In this brief report, 2 cases of fetal demise and 1 case of severe fetal distress in maternal delta-variant SARS-CoV-2 infection are presented. SARS-CoV-2 placentitis may be a potential mechanism for the increased risk of stillbirth observed in delta-variant COVID-19. Limited information is available on the specific impact of maternal infection with the SARS-CoV-2 B.1.617.2 (delta) variant on pregnancy outcomes.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Obstetrics & Gynecology
Maartje C. Snoep, Bo B. Bet, Fleur Zwanenburg, Ingmar Knobbe, Ingeborg H. Linskens, Eva Pajkrt, Lieke Rozendaal, Lotte E. Van der Meeren, Sally-Ann Clur, Monique C. Haak
Summary: This study analyzed the factors related to fetal demise in cases of fetal congenital heart disease. The findings showed that, in addition to cardiac failure and other (genetic) diagnoses, placental factors also play an important role in fetal demise, especially in cases of isolated heart defects. These results support the importance of regular ultrasound assessment of fetal growth and placental function in fetal congenital heart disease.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Erica Testani, Kristen Latta, Emily Barker, Sloane L. York, Laura Laursen
Summary: This study compared the complication rates of medical termination for fetal anomalies with medical termination for intrauterine fetal demise in the second trimester. The results showed that both groups had similar complication rates.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Medicine, General & Internal
Camelia Oualiken, Olivia Martz, Nadia Idrissi, Fara Tanjona Harizay, Laurent Martin, Emmanuel De Maistre, Lou Ricaud, Georges Tarris
Summary: Complicated pregnancies are a major concern due to the potential risks for both the mother and the fetus. Blood coagulation disorders and hypertensive gestational disorders are well-known contributors to poor outcomes, and placental vascular malformations can also lead to serious complications. This case study highlights the association between a heterozygous factor V Leiden mutation and umbilical artery aneurysm, which may have led to fetal demise.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Dana Anais Muin, Janina Sophie Erlacher, Stephanie Leutgeb, Anna Felnhofer
Summary: The study found that diagnosing fetal death is associated with moderate to high stress levels for obstetricians, with coping strategies including reliance on clinical knowledge, support from colleagues, and debriefing. Female, resident, and younger obstetricians are more likely to seek professional support and training when delivering difficult news. Both external and internal facilitators are important for obstetricians in communicating the diagnosis of fetal death.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Rinat Levi, Gali Pariente, Eyal Sheiner, Tamar Wainstock
Summary: This study identified risk factors in first pregnancy for perinatal mortality in the subsequent pregnancy, concluding that complications in first pregnancy ending with live birth are associated with increased risk for perinatal mortality in a subsequent pregnancy.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Obstetrics & Gynecology
Shinsuke Tokoro, Shigeki Koshida, Shunichiro Tsuji, Daisuke Katsura, Tetsuo Ono, Takashi Murakami, Kentaro Takahashi
Summary: This retrospective study reviewed all stillbirths in Shiga Prefecture, Japan, from 2007 to 2016 and found that only 39% of cases with fetal growth restriction (FGR) were identified antenatally. The antenatal identification of FGR was associated with the severity of growth restriction.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Medical Laboratory Technology
Irene Maria Beune, Stefanie Elisabeth Damhuis, Wessel Ganzevoort, John Ciaran Hutchinson, Teck Yee Khong, Eoghan E. Mooney, Neil James Sebire, Sanne Jehanne Gordijn
Summary: This study established a consensus-based definition for fetal growth restriction in fetal death through a modified online Delphi survey with an international panel of experts. The consensus definition included antenatal clinical diagnosis, birth weight criteria, and contributory variables, aiming to improve management and outcomes of subsequent pregnancies.
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2021)
Article
Multidisciplinary Sciences
Lucile Abiola, Guillaume Legendre, Andrew Spiers, Elsa Parot-Schinkel, Jean-Francois Hamel, Philippe Duverger, Pierre-Emmanuel Bouet, Philippe Descamps, Caroline Quelen, Philippe Gillard, Elise Riquin
Summary: Late-term fetal demise may lead to post-traumatic stress disorder (PTSD) symptoms, with factors such as peritraumatic dissociation, seeing the fetus, holding the fetus, and organizing a funeral service being associated. Care providers should exercise caution in high-risk situations to offer appropriate care.
SCIENTIFIC REPORTS
(2022)
Article
Virology
David A. Schwartz
Summary: Stillbirth in pregnant women with COVID-19 may occur due to placental infection, resulting in placental dysfunction and subsequent fetal death. The pathological lesions include increased fibrin deposition, trophoblast necrosis, and chronic histiocytic intervillositis. This destructive placental process can lead to stillbirth and neonatal death, independent of fetal infection. Maternal vaccination may help prevent viremia and consequent placental infection.
Article
Medicine, General & Internal
Giulia Ottaviani, Simone G. Ramos
Summary: Sudden unexpected death (SUD) is a fatal event that occurs suddenly in apparently healthy individuals without any prediction. SUD can occur as the first manifestation of an unknown underlying disease or within a few hours of the presentation of a disease. The study examined 75 SUD victims and found frequent congenital alterations of the cardiac conduction system in fetuses and infants.
Article
Anesthesiology
Beth A. VanderWielen, Ronen Harris, Richard E. Galgon, Lynn M. VanderWielen, Kristopher M. Schroeder
JOURNAL OF CLINICAL ANESTHESIA
(2015)
Article
Veterinary Sciences
K. R. Viviano, S. N. Lavergne, L. Goodman, B. VanderWielen, L. Grundahl, M. Padilla, L. A. Trepanier
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2009)
Article
Veterinary Sciences
K. R. Viviano, B. VanderWielen
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2013)
Article
Dermatology
Jenny Liu, Phillip T. Hsu, Beth A. VanderWielen, Joyce M. Teng
PEDIATRIC DERMATOLOGY
(2012)
Article
Anesthesiology
Beth VanderWielen, Lindsay Rubenstein, Marc Shnider, Cindy Ku, Jason Wakakuwa
A & A CASE REPORTS
(2017)