Article
Urology & Nephrology
Lilia Cervantes, Allison Tong, Claudia Camacho, Adriana Collings, Neil R. Powe
Summary: Providing healthcare access to standard dialysis for undocumented immigrants improved quality of life and mitigated debilitating symptoms, but brought new challenges in healthcare navigation, family burden, and work.
KIDNEY INTERNATIONAL
(2021)
Article
Cardiac & Cardiovascular Systems
Onkar Khullar, Aubriana Perez, Meredith Dixon, Jose N. Binongo, Manu S. Sancheti, Allan Pickens, Theresa Gillespie, Seth D. Force, Felix G. Fernandez
Summary: This study examined the success of routine patient-reported outcomes (PROs) assessment in an academic-based thoracic surgery practice. Results showed that out of 9725 thoracic surgery office visits, PROs data were obtained in 6899 visits from 3551 patients. The overall questionnaire completion rate was 65.7%, with a significant decline in April 2020. Rating: 8 out of 10.
ANNALS OF THORACIC SURGERY
(2023)
Review
Endocrinology & Metabolism
Per Karkov Cramon, Jakob Bue Bjorner, Mogens Groenvold, Victor Brun Boesen, Steen Joop Bonnema, Laszlo Hegedus, Ulla Feldt-Rasmussen, Ase Krogh Rasmussen, Torquil Watt
Summary: Patient-reported outcomes (PROs) are increasingly used in clinical practice to improve clinical care. However, successful implementation of PROs requires addressing barriers and challenges.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Janine Hawkins, Nigel Smeeton, Amanda Busby, David Wellsted, Beth Rider, Julia Jones, Retha Steenkamp, Catherine Stannard, Rachel Gair, Sabine N. van der Veer, Claire Corps, Ken Farrington
Summary: The study found that patient experience of care in advanced kidney disease patients undergoing maintenance haemodialysis is primarily determined by the characteristics of the treatment centre rather than the patients themselves. Further research is needed to identify the specific centre characteristics that impact patient experience.
Article
Gastroenterology & Hepatology
John E. Pandolfino, Dustin A. Carlson, Josie McGarva, Peter J. Kahrilas, Michael Vaezi, David Katzka, Tiffany H. Taft
Summary: The study developed a new Achalasia Patient-Reported Outcomes (APRO) Questionnaire, identified three subscales through investigation of patients with normal motility and achalasia, and found that symptom anxiety and hypervigilance moderate the relationship between APRO and quality of life.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Cardiac & Cardiovascular Systems
Adrienne H. Kovacs, Gerald Lebovic, Stavroula Raptis, Samuel Blais, Christopher A. Caldarone, Nagib Dahdah, Frederic Dallaire, Christian Drolet, Jasmine Grewal, Camille L. Hancock Friesen, Edward Hickey, Gauri Rani Karur, Paul Khairy, Benedetta Leonardi, Michelle Keir, Brian W. McCrindle, Syed Najaf Nadeem, Ming-Yen Ng, Ashish H. Shah, Edythe B. Tham, Judith Therrien, Andrew E. Warren, Isabelle F. Vonder Muhll, Alexander Van de Bruaene, Kenichiro Yamamura, Michael E. Farkouh, Rachel M. Wald
Summary: This study explored the relationship between pulmonary regurgitation and quality of life and health status in adults with Tetralogy of Fallot (TOF), and found that with advancing age, patients reported more problems in mobility and pain or discomfort. Factors associated with superior patient-reported outcomes include race, syndrome, employment, and left ventricular function, while being asymptomatic was found to have the greatest impact on quality of life and health status.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Urology & Nephrology
Qingyu Niu, Xinju Zhao, Liangying Gan, Xinling Liang, Zhaohui Ni, Xiaonong Chen, Yuqing Chen, Fan Fan Hou, Li Zuo
Summary: The study found that higher levels of self-reported physical function limitations were associated with increased risk of all-cause mortality and hospitalization in hemodialysis patients.
Article
Oncology
Myung-Kyung Lee, Jihyun Oh
Summary: Exercise can have a synergistic effect on improving health-related quality of life (HRQOL) and depression in patients with gastric cancer, by indirectly positively affecting depression and directly influencing HRQOL.
Article
Multidisciplinary Sciences
Xinju Zhao, Qingyu Niu, Liangying Gan, Fan Fan Hou, Xinling Liang, Zhaohui Ni, Yuqing Chen, Junhui Zhao, Brian Bieber, Bruce Robinson, Xiaonong Chen, Li Zuo
Summary: The number of hemodialysis patients in China is increasing rapidly, with most patients being older and primarily affected by chronic glomerulonephritis and diabetes. Some patients also have hepatitis B or C infections. The study provides insights into the demographic and clinical characteristics as well as treatment patterns of HD patients in China.
SCIENTIFIC REPORTS
(2021)
Review
Cardiac & Cardiovascular Systems
Gianluigi Savarese, Joann Lindenfeld, Davide Stolfo, Kirkwood Adams, Tariq Ahmad, Nihar R. R. Desai, Enrico Ammirati, Stephen S. S. Gottlieb, Mitchell A. A. Psotka, Giuseppe M. C. Rosano, Larry A. A. Allen
Summary: Heart failure is a complex syndrome that significantly impairs multiple aspects of daily activities and reduces the overall quality of life. Historically, the assessment of disease status and symptom severity has been solely based on physician evaluation, neglecting the patient's experience. Patient-reported outcomes (PROs) aim to shift towards a more patient-centered approach by involving patients in their own care. While PROs have shown precision in evaluating disease status and predicting prognosis in randomized controlled trials, their implementation in clinical practice remains limited. This review discusses the use of PROs in heart failure, the most commonly used PROs, their application in trials, and the potential for integrating PROs into routine clinical practice. By exploring the advantages, disadvantages, and strategies to promote their use, this review aims to encourage the systematic inclusion of the patient's perspective in heart failure care.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Oncology
Emily E. van Seventer, Madeleine G. Fish, Kathryn Fosbenner, Katie Kanter, Amirkasra Mojtahed, Jill N. Allen, Lawrence Blaszkowsky, Jeffrey W. Clark, Jon Dubois, Joseph W. Franses, Bruce J. Giantonio, Lipika Goyal, Samuel J. Klempner, Eric J. Roeland, David P. Ryan, Colin D. Weekes, Therese Mulvey, Areej El-Jawahri, Nora Horick, Ryan B. Corcoran, Aparna R. Parikh, Ryan D. Nipp
Summary: This study found that baseline patient-reported outcomes (PROs) are associated with treatment response, healthcare utilization, and survival in patients with advanced gastrointestinal cancer. Specifically, physical symptoms and functional quality of life were correlated with disease progression and survival.
Review
Dentistry, Oral Surgery & Medicine
Gotfredsen Klaus
Summary: Evidence-based dentistry involves using evidence from the literature, clinical expertise, and patient expectations to make decisions and assess treatment. Patient satisfaction can be evaluated using questionnaires or structured questions and includes affability, availability, and ability. Questionnaires such as the oral health impact profile (OHIP) or the dental impact on daily living (DIDL) can be used to assess patient perception and quality of life. Patient-reported outcome measures (PROMs) have shown to enhance patient engagement and should be integrated into clinical care.
PERIODONTOLOGY 2000
(2023)
Article
Surgery
S. R. Markar, V Sounderajah, A. Johar, G. Zaninotto, C. Castoro, P. Lagergren, J. A. Elliott, S. S. Gisbertz, C. Mariette, R. Alfieri, J. Huddy, E. Pinto, M. Scarpa, F. Klevebro, B. Sunde, C. F. Murphy, C. Greene, N. Ravi, G. Piessen, H. Brenkman, J. Ruurda, R. van Hillegersberg, S. M. Lagarde, B. P. Wijnhoven, M. Pera, J. Roigg, S. Castro, R. Matthijsen, J. Findlay, S. Antonowicz, N. Maynard, O. McCormack, A. Ariyarathenam, G. Sanders, E. Cheong, S. Jaunoo, W. Allum, J. van Lanschot, M. Nilsson, J. Reynolds, M. I. van Berge Henegouwen, G. B. Hanna
Summary: Long-term symptom burden is common after oesophageal cancer surgery, with symptoms clustering into six domains: lethargy, musculoskeletal pain, dumping, lower gastrointestinal symptoms, regurgitation/reflux, and swallowing problems. Factors associated with severe symptoms include surgical approach, neoadjuvant therapy, patient age, and sex.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Dermatology
Yael Renert-Yuval, Joel Correa da Rosa, Sandra Garcet, Ana B. Pavel, Jennifer Bares, Margot Chima, Jason E. Hawkes, Patricia Gilleaudeau, Mary Sullivan-Whalen, Giselle K. Singer, James G. Krueger, Emma Guttman-Yassky
Summary: This study investigated the utility of two different alopecia areata-targeted questionnaires, and found that the Alopecia Areata Symptom Impact Scale (AASIS) correlated strongly with alopecia areata severity and clinical response. Patients with <= 20% scalp hair loss after treatment reported improvement in multiple quality-of-life items, which may guide clinicians and improve the development of future clinical trials.
BRITISH JOURNAL OF DERMATOLOGY
(2022)
Article
Urology & Nephrology
Eiichiro Kanda, Daniel Muenz, Brian Bieber, Aleix Cases, Francesco Locatelli, Friedrich K. Port, Roberto Pecoits-Filho, Bruce M. Robinson, Jeffrey Perl
Summary: The study found a tenfold decrease in DRA-related hospitalization rates from 1998 to 2018. Even in the current era of high-flux HD, serum beta 2M remains positively associated with mortality, with mortality risk increasing monotonically with increasing beta 2M levels.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Urology & Nephrology
Tomoko Usui, Junhui Zhao, Douglas S. Fuller, Norio Hanafusa, Takeshi Hasegawa, Hiroshi Fujino, Takanobu Nomura, Jarcy Zee, Eric Young, Bruce M. Robinson, Masaomi Nangaku
Summary: In this study of 1044 haemodialysis patients, higher levels of FGF23 were associated with younger age, higher levels of various serum markers, and increased risks of ESA-hypo. The relationship between FGF23 and anaemia, particularly the elevated risks of ESA-hypo at low FGF23 levels, requires further confirmation in larger clinical studies.
Article
Urology & Nephrology
Ronald L. Pisoni, Lindsay Zepel, Junhui Zhao, Steven Burke, Charmaine E. Lok, Kenneth J. Woodside, Haimanot Wasse, Hideki Kawanishi, Douglas E. Schaubel, Jarcy Zee, Bruce M. Robinson
Summary: This study compared international differences in AVF patency and catheter dependence duration between the United States, Japan, and EUR/ANZ regions. Findings showed higher AVF patency in Japan, while longer catheter dependence duration was observed in the US and EUR/ANZ regions. The results emphasize the need to reevaluate practices for long-term access planning, especially in AVF maturation.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Transplantation
Nahid Tabibzadeh, Angelo Karaboyas, Bruce M. Robinson, Philipp A. Csomor, David M. Spiegel, Pieter Evenepoel, Stefan H. Jacobson, Pablo-Antonio Urena-Torres, Masafumi Fukagawa, Issa Al Salmi, Xinling Liang, Ronald L. Pisoni, Eric W. Young
Summary: The study found that patients with higher PTH levels before starting hemodialysis were more likely to be prescribed active vitamin D and calcimimetics during the first year of hemodialysis. Additionally, these patients had a higher risk of having PTH levels greater than 600pg/mL 9-12 months after starting hemodialysis.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Talerngsak Kanjanabuch, Pongpratch Puapatanakul, Guttiga Halue, Pichet Lorvinitnun, Kittisak Tangjittrong, Krit Pongpirul, Surapong Narenpitak, Chanchana Boonyakrai, Sajja Tatiyanupanwong, Rutchanee Chieochanthanakij, Worapot Treamtrakanpon, Uraiwan Parinyasiri, Niwat Lounseng, Phichit Songviriyavithaya, Suchai Sritippayawan, Jeffrey Perl, Roberto Pecoits-Filho, Bruce Robinson, Simon J. Davies, David W. Johnson, Kriang Tungsanga
Summary: The PD Outcomes and Practice Patterns Study in Thailand revealed high prevalence of hypokalaemia, anaemia, poor nutritional status and culture-negative peritonitis among PD patients in the country. Patients from Bangkok metropolitan region showed better outcomes compared to provincial regions, emphasizing the impact of the center on key success factors in PD.
PERITONEAL DIALYSIS INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Suguru Yamamoto, Brian A. Bieber, Hirotaka Komaba, Norio Hanafusa, Hiroki Kitabayashi, Takanobu Nomura, Aleix Cases, Christian Combe, Ronald L. Pisoni, Bruce M. Robinson, Masafumi Fukagawa
Summary: This study investigated the association between medical director's practice of recommending an increase in dietary protein intake and outcomes in hemodialysis patients. It found that this practice was associated with lower mortality and higher serum creatinine levels.
JOURNAL OF RENAL NUTRITION
(2022)
Article
Transplantation
Amelie Kurnikowski, Simon Krenn, Michal J. Lewandowski, Elisabeth Schwaiger, Allison Tong, Kitty J. Jager, Juan Jesus Carrero, Manfred Hecking, Sebastian Hoedlmoser
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Urology & Nephrology
Oskar Swartling, Yuanhang Yang, Catherine M. Clase, Edouard L. Fu, Manfred Hecking, Sebastian Hoedlmoser, Ylva Trolle-Lagerros, Marie Evans, Juan J. Carrero
Summary: This study evaluated the sex differences in CKD patients and found that the disparities may be explained by differences in healthcare.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Engineering, Biomedical
Daniel Schneditz, Sebastian Mussnig, Simon Krenn, Manfred Hecking
Summary: The current estimation of body fluid volumes in hemodialysis patients using bioimpedance analysis assumes constant specific electrical characteristics of biological tissues despite a large variation in plasma Na+ concentrations [Na+]. This study examined the potential effect of variable [Na+] on bioimpedance-derived volume overload and found that the increase in volume overload was abolished when the same bioimpedance data were analyzed under revised conditions that account for differences in tissue electrical properties using individual [Na+]. The overestimation in extracellular volume overload caused by the variation in [Na+] may become important when comparing data of larger patient groups.
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
(2023)
Article
Nutrition & Dietetics
Sebastian Mussnig, Michael Schmiedecker, Maximilian Waller, Janosch Niknam, Christopher Paschen, Daniel Schneditz, Manfred Hecking, Simon Krenn
Summary: This study aimed to compare the differences between two versions (3.2.5 and 3.3.3) of the Body Composition Monitor (BCM) in measuring body impedance, fat and lean tissue mass, fluid compartments, and overhydration. The results showed significant differences between the two versions of the BCM in terms of overhydration, with the newer version 3.3.3 tending to measure less overhydration. Therefore, it is important to check the version of the BCM device and use devices of the same version for each patient to ensure better within-patient consistency.
Article
Urology & Nephrology
Patrizia Natale, Manfred Hecking, Amelie Kurnikowski, Nicole Scholes-Robertson, Juan Jesus Carrero, Germaine Wong, Giovanni Strippoli, Allison Jaure
Summary: There is a gender disparity in access to kidney transplantation, with women being 20% less likely to receive a transplant compared to men across different backgrounds and socioeconomics. Nephrologists perceive that this disparity is exacerbated by gender norms, stigma, prejudice, and educational and financial disadvantages faced by women.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Editorial Material
Transplantation
Maximilian Waller, Simon Krenn, Sebastian Mussnig, Michael Schmiedecker, Janosch Niknam-Saeidi, Christopher C. Mayer, Peter Wabel, Daniel Schneditz, Charles Chazot, Manfred Hecking
Summary: This article provides a video link to watch the related content.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Review
Urology & Nephrology
Nicholas C. Chesnaye, Juan Jesus Carrero, Manfred Hecking, Kitty J. Jager
Summary: Improved understanding of gender differences in kidney disease epidemiology, management, and outcomes is crucial to provide better care to patients. Women have a higher prevalence of early-stage chronic kidney disease, while men have a higher risk of kidney function decline, kidney failure, and cardiovascular disease. However, the protective effect of female sex diminishes with disease progression. Women are less likely to be diagnosed and treated for kidney disease and have lower health-related quality of life. They face more barriers to access the transplant waiting list but have better survival after transplantation.
NATURE REVIEWS NEPHROLOGY
(2023)
Article
Urology & Nephrology
Daniel Schneditz, Peter Hofmann, Simon Krenn, Maximilian Waller, Sebastian Mussnig, Manfred Hecking
Summary: Short-term variability in body mass is common but data on this variability is limited. For individuals with impaired volume homeostasis, such as kidney failure patients, body mass variability should be taken into consideration during therapy. The study found that body mass relative differences remained constant over time.
Meeting Abstract
Surgery
Amelie Kurnikowski, Simon Krenn, Michal J. Lewandowski, Elisabeth Schwaiger, Allison Tong, Kitty J. Jager, Juan Jesus Carrero, Manfred Hecking, Sebastian Hoedlmoser
TRANSPLANT INTERNATIONAL
(2021)
Article
Urology & Nephrology
Carolin Berner, Rodrig Marculescu, Florian Frommlet, Amelie Kurnikowski, Benjamin Schairer, Christof Aigner, Christian Bieglmayer, Manfred Hecking
Summary: The study compared biointact and intact immunoassays for measuring PTH concentrations in hemodialysis patients. The results showed that wPTH concentrations were similar between the two types of assays, while iPTH concentrations were higher than wPTH concentrations. All tested immunoassays demonstrated good agreement in detecting changes in PTH concentrations, with the ability to accurately identify significant and insignificant changes.