Article
Public, Environmental & Occupational Health
Renee Lehane, Catherine Svensson, Jennifer A. Ormsby, Jenny Chan Yuen, Gregory P. Priebe, Thomas J. Sandora, Ana M. Vaughan-Malloy
Summary: The study implemented hospital-wide urinary catheter K-card rounding, which significantly improved the reliability of catheter maintenance bundle and reduced the CAUTI rates.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Article
Immunology
Jennifer A. Frontera, Erwin Wang, Michael Phillips, Martha Radford, Stephanie Sterling, Karen Delorenzo, Archana Saxena, Shadi Yaghi, Ting Zhou, D. Ethan Kahn, Aaron S. Lord, Joseph Weisstuch
Summary: The novel protocol for urine sampling and testing significantly reduced rates of CAUTI infection and urinary catheter days.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Moi Lin Ling, P. Ching, A. Apisarnthanarak, N. Jaggi, G. Harrington, S. M. Fong
Summary: The Asia Pacific Society of Infection Control launched a guide for the prevention of catheter-associated urinary tract infections in July 2022. It provides practical recommendations to assist healthcare facilities in the Asia Pacific region in achieving high standards in infection prevention and control.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2023)
Article
Infectious Diseases
Leyland Chuang, Paul Anantharajah Tambyah
Summary: This guideline provides updated recommendations on the management and prevention of CAUTIs by the Urological Association of Asia and the Asian Association of Urinary Tract Infection and Sexually Transmitted Infection.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2021)
Review
Public, Environmental & Occupational Health
Najla A. Obaid
Summary: CAUTI is a common infection that occurs in clinical practice in ICUs and non-ICU departments, with studies in Saudi Arabia mainly focusing on the ICU setting. More interventional and epidemiological studies are needed to understand the causes and factors affecting the rate of CAUTI in the area.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2021)
Article
Infectious Diseases
Osman Mohammed, Sisay Gedamu, Endalk Birrie, Ali Seid, Abebe Dires, Debrnesh Goshiye
Summary: A substantial proportion of health care workers in South Wollo zone public hospitals have inadequate knowledge and practice towards prevention of catheter-associated urinary tract infections. Training and educational qualifications are significantly associated with adequate knowledge, while higher qualifications, adequate knowledge, training, and longer work experience are significantly associated with adequate practice.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Medicine, General & Internal
Mohd Saleem, Azharuddin Sajid Syed Khaja, Ashfaque Hossain, Fahaad Alenazi, Kamaleldin B. Said, Soha Abdallah Moursi, Homoud Abdulmohsin Almalaq, Hamza Mohamed, Ehab Rakha, Sunit Kumar Mishra
Summary: Catheter-associated urinary tract infections (CAUTIs) are a common type of hospital-acquired infection, often occurring in ICU patients with catheters. This study provides information on CAUTI incidence rates and antibiogram patterns of causative organisms in a tertiary care hospital in Hail, Saudi Arabia, which can be used to develop effective antibiotic stewardship programs.
Article
Public, Environmental & Occupational Health
Curtis Warren, Jaclyn D. Fosnacht, Elizabeth E. Tremblay
Summary: The introduction of external female urinary catheters has successfully decreased the utilization of indwelling urinary catheters, particularly in intensive care units. Therefore, it is recommended that healthcare facilities focus on implementing this device first in ICUs.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Review
Medicine, General & Internal
Brett Mitchell, Cassie Curryer, Elizabeth Holliday, Claire M. Rickard, Oyebola Fasugba
Summary: The systematic review indicates that using antiseptic agents for meatal cleaning may help prevent bacteriuria and catheter-associated urinary tract infections (CAUTIs), with chlorhexidine and povidine-iodine showing potential benefits in reducing CAUTI incidence.
Review
Immunology
Shobana Rajaramon, Karthi Shanmugam, Rambabu Dandela, Adline Princy Solomon
Summary: Healthcare settings have made significant advancements in using urinary catheters (UC) to prevent and control infections. However, the continuous or intermittent flow of urine in the UC promotes the formation of biofilms and encrustations, increasing the risk of urinary tract infections (CAUTI). This review comprehensively discusses the challenges posed by CAUTI and its associated risks on patient morbidity and mortality. Furthermore, it provides detailed information on various strategies that modify the surface properties of UC to prevent fouling, kill bacteria, and reduce adhesion, offering insights on better management with futuristic solutions.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Immunology
Virginia Perez-Carrasco, Ana Soriano-Lerma, Miguel Soriano, Jose Gutierrez-Fernandez, Jose A. Garcia-Salcedo
Summary: The application of next generation sequencing techniques has revealed that the urinary tract is not sterile, contrary to previous beliefs. Microbial communities in the urinary tract play a crucial role in maintaining health and are associated with various urinary pathologies. Understanding the urinary microbiome in health and disease could lead to the development of new therapeutic strategies.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Ylva Kai-Larsen, Stefan Grass, Bhaumik Mody, Swati Upadhyay, Hargovind L. Trivedi, Dilip K. Pal, Santosh Babu, Bikash Bawari, Shrawan K. Singh
Summary: The study aimed to evaluate the efficacy of a noble metal alloy (NMA) coated BIP Foley Catheter in preventing symptomatic CAUTI in a large cohort of patients in India. The results showed a 69% reduction in CAUTI with the NMA-coated BIP Foley Catheter group compared to the control group, with fewer adverse events in the NMA-coated group.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2021)
Article
Public, Environmental & Occupational Health
Lindsey Rearigh, Gayle Gillett, Adrienne Sy, Terry Micheels, Luana Evans, Kelly Goetschkes, Trevor C. Van Schooneveld, Elizabeth Lyden, Mark E. Rupp
Summary: The study demonstrated that implementing EUCDs in women significantly reduced the use of indwelling catheters and showed a trend towards decreased CAUTI rates per 1,000 patient days.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Medicine, General & Internal
Jung Ki Jo, Dong Seob Kim, Younghun Sim, Soorack Ryu, Kyu Shik Kim
Summary: The study found that the severity of UTI is higher in patients with catheters, and the infecting strains vary depending on the presence of a catheter. Fosfomycin has a success rate of over 50% in treating UTIs, even in patients with catheters.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Hodam Rubi, Gargi Mudey, Radha Kunjalwar
Summary: Catheter-associated urinary tract infection (CAUTI) is one of the most prevalent health-related illnesses worldwide, accounting for nearly half of all hospital-acquired diseases. The use of catheter tubes is the primary cause of healthcare-acquired urinary tract infections. Minimizing catheter usage and removing them as soon as medically possible are crucial preventive measures. Infection control guidelines play a vital role in monitoring and implementing efforts to prevent catheter-acquired infections.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Statistics & Probability
Matteo Bonvini, Edward H. Kennedy
Summary: This article introduces a novel sensitivity analysis approach, with the sensitivity parameter set as the proportion of unmeasured confounding, to investigate the impact of unmeasured confounders on research outcomes. By making different probability assumptions, sharp boundaries on the average treatment effect are derived, and nonparametric estimators are proposed for flexible covariate adjustment. Additionally, a one-number summary is introduced to assess the robustness of the study to the number of confounded units.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
(2022)
Article
Public, Environmental & Occupational Health
Gabriel Conzuelo Rodriguez, Lisa M. Bodnar, Maria M. Brooks, Abdus Wahed, Edward H. Kennedy, Enrique Schisterman, Ashley Naimi
Summary: This study compared the performance of correctly specified parametric models and nonparametric models in evaluating effect modification. The findings suggest that generalized linear models have the highest power for detecting effect modification with binary exposures, while the DR-learner is comparable to flexible parametric models for continuous modifiers, especially in capturing quadratic and nonlinear monotonic functions.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Editorial Material
Public, Environmental & Occupational Health
Ashley Naimi, Alan E. Mishler, Edward H. Kennedy
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Mathematical & Computational Biology
Youjin Lee, Edward H. Kennedy, Nandita Mitra
Summary: This article proposes nonparametric estimators for addressing censored survival outcomes, providing estimates for the local average treatment effect on survival probabilities. The proposed estimators possess double-robustness properties and can easily incorporate nonparametric estimation using machine learning tools. Simulation studies demonstrate the flexibility and double robustness of the proposed estimators.
Article
Mathematical & Computational Biology
Asma Bahamyirou, Mireille E. Schnitzer, Edward H. Kennedy, Lucie Blais, Yi Yang
Summary: This paper proposes a two-stage procedure to automatically select effect modifying variables in a Marginal Structural Model (MSM), and verifies its performance through simulation studies and analysis of pregnancy data.
INTERNATIONAL JOURNAL OF BIOSTATISTICS
(2022)
Article
Public, Environmental & Occupational Health
Sanjay Saint, M. Todd Greene, Sarah L. L. Krein, Karen E. E. Fowler, Kathleen A. A. Linder, David Ratz, Jennifer Meddings
Summary: This study aimed to investigate the changes in device-associated infection prevention practices during the COVID-19 pandemic. Data collected mid-pandemic were used to assess the use of several infection prevention practices and compare them with historical data. The results showed that the use of preventive practices for CLABSI and VAE continued to increase or plateau, while the use of preventive practices for CAUTI decreased.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jonathan D. Baghdadi, Lyndsay M. O'Hara, J. Kristie Johnson, Sarah L. Krein, Anthony D. Harris, Daniel J. Morgan
Summary: This study described best practices in the implementation of multiplex PCR respiratory panels based on expert perspectives, and identified tools for diagnostic stewardship to enhance the usefulness of testing. The survey results showed that multiplex PCR respiratory panels were perceived as supporting accurate diagnoses, more efficient patient care, and improving patient outcomes. Diagnostic stewardship interventions, including structured order sets, restrictions on test ordering, and structured communication of results, were reported as effective measures to enhance the usefulness of testing.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Amanda L. Missel, Stephen R. Dowker, Drake Dzierwa, Sarah L. Krein, Emilee I. Coulter-Thompson, Michelle Williams, Brad Trumpower, Robert Swor, Nathaniel Hunt, Charles P. Friedman
Summary: Through group interviews with emergency responders, factors that affect the treatment of out-of-hospital cardiac arrest patients were studied, including issues in the areas of structure, process, system, and continuous quality improvement. Rapid implementation interventions or programs include improving prearrival communication between agencies, appointing patient care and logistical leadership on-scene, interstakeholder team training, and providing more standardized feedback to all responder groups to improve outcomes for out-of-hospital cardiac arrest patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Tiffany Christine Veinot, Brenda Gillespie, Marissa Argentina, Jennifer Bragg-Gresham, Dinesh Chatoth, Kelli Collins Damron, Michael Heung, Sarah Krein, Rebecca Wingard, Kai Zheng, Rajiv Saran
Summary: This study aims to evaluate the effectiveness of two interventions on reducing intradialytic hypotension (IDH) in hemodialysis facilities. The interventions include provider education and patient activation. The primary outcome is the proportion of treatments with IDH, and secondary outcomes include patient symptoms, hospitalizations, and mortality.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Public, Environmental & Occupational Health
Kimberly C. Claeys, Lauren E. Weston, Lisa Pineles, Daniel J. Morgan, Sarah L. Krein
Summary: This study aimed to identify the barriers to and facilitators of diagnostic stewardship implementation in urine-culture diagnostic practices for urinary tract infections (UTIs) by conducting interviews and comparing practices and perceptions across three Veterans' Affairs medical centers. The majority of participants recognized the importance of diagnostic stewardship, but perceptions of specific interventions varied widely across sites.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Karen M. Jones, Sarah L. Krein, Julia Mantey, Molly Harrod, Lona Mody
Summary: This study assessed the resources and practices of infection prevention and control programs in nursing homes in the United States, specifically related to the prevention of catheter and non-catheter-associated urinary tract infections. The findings showed that nursing homes had some awareness of urinary tract infections and implemented prevention practices, but there were challenges in terms of training and education for infection preventionists, as well as communication between nursing homes and hospitals.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Editorial Material
Oncology
Phoebe A. Tsao, Jesse R. Fann, Andrea L. Nevedal, Lindsey E. Bloor, Sarah L. Krein, Megan E. V. Caram
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Health Care Sciences & Services
Milan Patel, Hanna Berlin, Abishek Rajkumar, Sarah L. Krein, Rebecca Miller, Jessie DeVito, Jake Roy, Margaret Punch, Chad Ellimootti, Alex F. Peahl
Summary: Although telemedicine is a promising approach for improving access to care, its use has decreased in many medical specialties. Understanding the barriers and facilitators to web-based visits is critical for ensuring the continuous availability of telemedicine for patients.
JMIR HUMAN FACTORS
(2023)
Article
Nanoscience & Nanotechnology
Shipra Saini, Namita Bindal, Brajesh Kumar Kaushik
Summary: Using first-principle calculations, the authors observe variations in magnetic anisotropy energy and other magnetic properties for transition metal (TM) doped bismuth monolayer. The Mn-doped bismuthene exhibits half-metallicity with higher magnetic moment and magnetic anisotropy energy compared to Fe-doped and Ti-doped systems. The half-metal Mn-Bi can induce half-metallicity in CrI3 through charge transfer, making it the most favorable doped system for spintronic device development in Mn-Bi/CrI3 van der Waals heterostructure.
IEEE OPEN JOURNAL OF NANOTECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jacqueline E. Rudolph, Kwangho Kim, Edward H. Kennedy, Ashley I. Naimi
Summary: This study aims to assess the incremental effects of time-varying exposure, using data from an experiment on the impact of aspirin on pregnancy outcomes. The results suggest that increasing women's probability of taking aspirin has little impact on pregnancy rates.