Review
Medicine, General & Internal
Fabio Angeli, Gianpaolo Reboldi, Francesco Giuseppe Solano, Antonietta Prosciutto, Antonella Paolini, Martina Zappa, Claudia Bartolini, Andrea Santucci, Stefano Coiro, Paolo Verdecchia
Summary: Several outcome-based prospective investigations have shown the prognostic value of 24-hour ambulatory blood pressure monitoring in cardiovascular risk stratification. Average 24-hour, daytime, and nighttime blood pressures are essential components that improve risk assessment beyond traditional factors. However, the interpretation and clinical use of ambulatory blood pressure monitoring need standardization, and implementing its results in individual patient management remains challenging.
Article
Peripheral Vascular Disease
Kazuomi Kario, Hisashi Kai, Shinsuke Nanto, Hiroyoshi Yokoi
Summary: Maintaining medication adherence is crucial in treating hypertension, particularly resistant hypertension. This post-hoc analysis examined adherence in the REQUIRE trial, comparing the effects of ultrasound renal denervation (uRDN) versus sham in patients with resistant hypertension. The results showed that poorly adherent patients had different outcomes depending on the treatment group, highlighting the importance of monitoring and maintaining medication adherence in future studies.
HYPERTENSION RESEARCH
(2023)
Article
Medicine, General & Internal
Akshaya Srikanth Bhagavathula, Syed Mahboob Shah, Elhadi Husein Aburawi
Summary: The study found a high prevalence of TRH among newly treated hypertensive patients in the UAE, with suboptimal medication adherence and blood pressure control among participants, highlighting the urgent need for greater efforts to improve adherence to antihypertensive therapy and focus on TRH and blood pressure control.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Matthew J. J. Thompson, Melissa L. L. Anderson, Andrea J. J. Cook, Kelly Ehrlich, Yoshio N. N. Hall, Clarissa Hsu, Karen L. L. Margolis, Jennifer B. B. McClure, Sean A. A. Munson, Beverly B. B. Green
Summary: This study compared the acceptability and adherence of blood pressure (BP) measurement in clinic, home, kiosk, and ambulatory BP monitoring (ABPM) settings. The results showed that home BP measurement was the most acceptable, followed by clinic, kiosk, and ABPM. These findings support the routine use of home-based BP measurement in primary care practice in the US.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
Eline H. Groenland, Jean-Paul A. C. Vendeville, Remy H. H. Bemelmans, Houshang Monajemi, Michiel L. Bots, Frank L. J. Visseren, Wilko Spiering
Summary: This study evaluated the agreement between app-assisted home blood pressure monitoring and 24-hour ambulatory blood pressure monitoring, and found significant disagreement between the two methods. App-assisted home blood pressure monitoring had high sensitivity in diagnosing sustained and masked hypertension, and can be used as a complement to 24-hour ambulatory blood pressure monitoring.
Review
Medicine, General & Internal
Yibang Cheng, Yan Li, Jiguang Wang
Summary: Ambulatory blood pressure monitoring is crucial in the management of hypertension, as it aids in accurate diagnosis and cardiovascular risk assessment.
CHINESE MEDICAL JOURNAL
(2022)
Article
Peripheral Vascular Disease
Keisuke Narita, Satoshi Hoshide, Kazuomi Kario
Summary: This study analyzed the association between home and ambulatory blood pressure monitoring and cardiovascular risk in hypertensive outpatients, and found that both home blood pressure and ambulatory blood pressure were independently associated with cardiovascular risk. Home blood pressure had a modest superiority to predict cardiovascular prognosis compared to ambulatory blood pressure.
Article
Peripheral Vascular Disease
Ming-Hui Hung, Chin-Chou Huang, Chia-Min Chung, Jaw-Wen Chen
Summary: This study found that short-term blood pressure variability was not strongly associated with hypertensive nephropathy in Han Chinese individuals with hypertension, while 24-hour average blood pressure was more closely related to hypertensive nephropathy.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Article
Endocrinology & Metabolism
Leif Karlsson, Lena Wallensteen, Anna Nordenstrom, Rafael T. Krmar, Svetlana Lajic
Summary: This study analyzed ambulatory blood pressure measurements in children and adults who were treated with dexamethasone (DEX) prenatally. The results suggest that DEX treatment does not adversely affect blood pressure in individuals unaffected by congenital adrenal hyperplasia.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Peripheral Vascular Disease
Louise Keehn, Wendy L. Hall, Sarah E. Berry, Thomas A. B. Sanders, Phil Chowienczyk, Christopher N. Floyd
Summary: This study aimed to determine the reproducibility of ambulatory blood pressure monitoring (ABPM) in normotensive and well controlled hypertensive individuals. The results showed that single ABPM measurements have considerable variability, potentially leading to misclassification of hypertension status and incorrect treatment regimes. Therefore, repeated ABPM may be necessary to refine antihypertensive therapy.
JOURNAL OF HYPERTENSION
(2022)
Article
Medicine, General & Internal
Francesca Coccina, Paola Borrelli, Anna M. M. Pierdomenico, Jacopo Pizzicannella, Maria T. T. Guagnano, Chiara Cuccurullo, Marta Di Nicola, Giulia Renda, Oriana Trubiani, Francesco Cipollone, Sante D. D. Pierdomenico
Summary: The aim of this study was to provide prediction models for masked uncontrolled hypertension (MUCH) detected by ambulatory blood pressure (BP) monitoring in an Italian population. The study found that males, smokers, left ventricular hypertrophy, and high-normal clinic blood pressure are indicators of MUCH, and the models including these factors have good diagnostic accuracy.
Article
Peripheral Vascular Disease
Byron C. Jaeger, Oluwasegun P. Akinyelure, Swati Sakhuja, Joshua D. Bundy, Cora E. Lewis, Yuichiro Yano, George Howard, Daichi Shimbo, Paul Muntner, Joseph E. Schwartz
Summary: Measuring blood pressure three to four times during sleep may have high agreement with nocturnal hypertension status based on a full night of ambulatory blood pressure monitoring.
HYPERTENSION RESEARCH
(2021)
Review
Public, Environmental & Occupational Health
Simao Pinho, Mariana Cruz, Filipa Ferreira, Andre Ramalho, Rute Sampaio
Summary: The study conducted a scoping review of medication adherence interventions in hypertensive patients and developed an evidence-based categorization system for interventions. Through analyzing 45 articles, detailed evaluations were provided on research design, participant characteristics, adherence strategies, as well as medication adherence and blood pressure outcomes. This work is significant in advancing future research efforts and providing valuable information to clinicians.
PREVENTIVE MEDICINE
(2021)
Article
Clinical Neurology
Lourdes M. DelRosso, Jeremy Chan, Chris Ruth, Weston T. Powell, Michelle Arp, Coral Hanevold, Raffaele Ferri
Summary: ABPM is recommended for early detection of nocturnal hypertension in children at high risk, such as obesity or OSA. This study shows that concurrent use of ABPM during PSG can aid in early identification of nocturnal hypertension in this population.
JOURNAL OF SLEEP RESEARCH
(2021)
Review
Medicine, General & Internal
Walter G. Espeche, Martin R. Salazar
Summary: Hypertension disorders during pregnancy range from mild to life-threatening. Office BP is currently the main method for diagnosis, but has limitations. ABPM plays a role in evaluating BP levels in pregnant women, particularly before 20 weeks and between 20-30 weeks, to classify HDP and detect high-risk women. It can also help identify masked chronic hypertension in women with office BP > 125/75 mmHg and assess long-term cardiovascular risk in women with PE.
Article
Cardiac & Cardiovascular Systems
Fu Guan, Ardan M. Saguner, Daniel Hofer, Thomas Wolber, Alexander Breitenstein, Nazmi Krasniqi, Urs Eriksson, Jan Steffel, Corinna Brunckhorst, Firat Duru
Summary: This study aimed to investigate the characteristics of His bundle potentials in patients with symptomatic atrioventricular nodal reentrant tachycardia (AVNRT) and to determine whether they can provide clues for the identification of slow pathway (SP). The study found that the amplitude and duration of HBmax were higher and longer, respectively, in patients with AVNRT compared to those with atrioventricular reentrant tachycardia (AVRT).
CARDIOLOGY JOURNAL
(2023)
Article
Multidisciplinary Sciences
Ibrahim El-Battrawy, Boldizsar Kovacs, Tobias C. Dreher, Norbert Klein, Stephanie Rosenkaimer, Susanne Roger, Jurgen Kuschyk, Ardan Muammer Saguner, Jacqueline Kowitz, Julia W. Erath, Firat Duru, Ibrahim Akin
Summary: Patients at high risk for sudden cardiac death may benefit from wearable cardioverter defibrillators by avoiding immediate implantable cardioverter defibrillator implantation. Factors such as patient selection, compliance, and drug treatment play important roles. This study presents real world data from Germany and Switzerland, analyzing outcome data and patient characteristics.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Sarah Costa, Kristina Koch, Alessio Gasperetti, Deniz Akdis, Corinna Brunckhorst, Guan Fu, Felix C. Tanner, Frank Ruschitzka, Firat Duru, Ardan M. Saguner
Summary: This study investigated the exercise performance and ventricular function of ARVC patients during follow-up, taking into account their adherence to exercise restriction recommendations. The results showed that if intensive sports activities are not discontinued, exercise capacity and left ventricular function of athletes with ARVC deteriorates over time. Therefore, it is essential for all ARVC patients to strictly adhere to the recommendation to cease intense sports activity in order to halt disease progression.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mohammad Abumayyaleh, Tobias C. Dreher, Stephanie Rosenkaimer, Susanne Roeger, Julia W. Erath, Norbert Klein, Boldizsar Kovacs, Firat Duru, Ardan M. Saguner, Ibrahim El-Battrawy, Ibrahim Akin
Summary: Compliance for wearing WCD was excellent regardless of sex. Furthermore, mortality and the incidence of ICD implantations were comparable in both sexes. Appropriate WCD shocks were similar in both sexes.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Christian-H Heeger, Sorin Stefan Popescu, Christian Sohns, Alexander Pott, Andreas Metzner, Osamu Inaba, Florian Straube, Malte Kuniss, Arash Aryana, Shinsuke Miyazaki, Serkan Cay, Joachim R. Ehrlich, Ibrahim El-Battrawy, Martin Martinek, Ardan M. Saguner, Verena Tscholl, Kivanc Yalin, Evgeny Lyan, Wilber Su, Giorgi Papiashvili, Maichel Sobhy Naguib Botros, Alessio Gasperetti, Riccardo Proietti, Erik Wissner, Daniel Scherr, Masashi Kamioka, Hisaki Makimoto, Tsuyoshi Urushida, Tolga Aksu, Julian K. R. Chun, Kudret Aytemir, Ewa Jedrzejczyk-Patej, Karl-Heinz Kuck, Tillman Dahme, Daniel Steven, Philipp Sommer, Roland Richard Tilz
Summary: CB-based PVI is an effective treatment for AF, but the most common complication is PNI. Our study found a high rate of reconnection during repeat procedures. These findings can help identify the optimal dosing protocol in CB-based PVI procedures.
Article
Medicine, General & Internal
Alper Gok, Mehmet Altan, Ahmet Emin Dogan, Asir Eraslan, Fahrettin Samil Uysal, Ufuk Ozturk, Ardan Muammer Saguner, Muhammet Abdurrahim Imamoglu
Summary: This study aimed to examine the changes in the frequency of erectile dysfunction after COVID-19 and whether the condition improves over time. The results showed that there may be a deterioration in erectile function after COVID-19, but it tends to improve, especially from the first year after the initial infection.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Tolga Cimen, Argelia Medeiros-Domingo, Antonios Kolios, Deniz Akdis, Shehab Anwer, Felix C. C. Tanner, Corinna Brunckhorst, Firat Duru, Ardan M. M. Saguner
Summary: In this case report, a 58-year-old male patient with cardiomyopathy and palmoplantar keratosis is described. Genetic testing revealed a novel variant in the desmoplakin gene, suggesting the presence of Cardiocutaneous syndrome. Repeated genetic testing is clinically significant, especially in patients with a high probability of a specific inherited cardiac disease, to improve diagnostic accuracy.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Iva Krizanovic-Grgic, Shehab Anwer, Jan Steffel, Daniel Hofer, Ardan M. Saguner, Christina M. Spengler, Alexander Breitenstein, Felix C. Tanner
Summary: This study investigated the association of 2D and 3D left atrial strain with low-voltage area in relation to the recurrence of atrial fibrillation after pulmonary vein isolation. The results showed that 3D left atrial reservoir strain and pump strain were lower in patients with recurrent AF. Furthermore, the association of 3D left atrial strain with recurrence of AF was independent of other clinical and echocardiographic parameters, making it a potential predictor for outcomes in patients undergoing PVI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Stephanie M. van der Voorn, Mimount Bourfiss, Steven A. Muller, Tolga Cimen, Ardan M. Saguner, Firat Duru, Anneline S. J. M. te Riele, Carol Ann Remme, Toon A. B. van Veen
Summary: Arrhythmogenic cardiomyopathy (ACM) is characterized by a fibro-(fatty) replacement of the myocardium. However, current cardiac imaging modalities have limitations in detecting fibrosis patterns. In this study, serum samples were collected from 45 ACM patients and the levels of PICP and ICTP were measured. The results showed that diagnosed patients had higher levels of PICP and PICP/ICTP compared to preclinical variant carriers, indicating an increased collagen deposition. Furthermore, negative correlations were found between PICP/ICTP ratio and right ventricular ejection fractions, as well as significant correlations with left ventricular function. These findings suggest that PICP/ICTP levels may serve as potential biomarkers for ACM.
Article
Cardiac & Cardiovascular Systems
Claudia Herrera Siklody, Luis Schiappacasse, Raphael Jumeau, Tobias Reichlin, Ardan M. Saguner, Nicolaus Andratschke, Olgun Elicin, Frederic Schreiner, Boldizsar Kovacs, Michael Mayinger, Adrian Huber, Joost J. C. Verhoeff, Patrizio Pascale, Jorge Solana Munoz, Adrian Luca, Giulia Domenichini, Raphael Moeckli, Jean Bourhis, Esat M. Ozsahin, Etienne Pruvot
Summary: This study analyzed recurrences in patients after Stereotactic Arrhythmia Radioablation (STAR) treatment. It was found that VT recurrences were common, but no recurrences were observed inside the planning target volume (PTV), indicating the local efficacy of STAR.
Article
Biochemistry & Molecular Biology
Stephanie M. van der Voorn, Esmee van Drie, Virginnio Proost, Kristina Dimitrova, Robert F. Ernst, Cynthia A. James, Crystal Tichnell, Brittney Murray, Hugh Calkins, Ardan M. Saguner, Firat Duru, Patrick T. Ellinor, Connie R. Bezzina, Sean J. Jurgens, J. Peter van Tintelen, Toon A. B. van Veen
Summary: This study investigated the impact of the p.(Ser96Ala) polymorphism in the HRC gene on cardiomyopathy and found no association with life-threatening arrhythmias or heart failure-related events, suggesting a lack of evidence supporting its role as a modifier in cardiomyopathy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Valerie Schutz, Svetlana Dougoud, Katja Bracher, Markus Arnold, Juliane Schweizer, Christos Nakas, Laura P. Westphal, Corinne Inauen, Thomas Pokorny, Firat Duru, Jan Steffel, Andreas Luft, Katharina Spanaus, Ardan Muammer Saguner, Mira Katan
Summary: This study aimed to evaluate the predictive value of pre-determined ECG criteria for newly diagnosed atrial fibrillation (NDAF) in unselected AIS patients. It was found that advanced interatrial block (aIAB) is an independent predictor of NDAF, and adding it to a multivariable regression model improves the accuracy of prediction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Francois Diederik Regoli, Ardan M. Saguner, Angelo Auricchio, Andrea Demarchi, Elena Pasotti, Giulio Conte, Maria Luce Caputo, Tardu Ozkartal, Alexander Breitenstein
Summary: This study aimed to evaluate a standardized DOAC management regime for TPS implantations and identify patient clinical characteristics associated with this approach. The results showed that the standardized approach was more often implemented for elective TPS procedures and did not increase bleeding or thromboembolic adverse events.
JOURNAL OF CLINICAL MEDICINE
(2023)
Meeting Abstract
Medicine, General & Internal
M. F. Reiner, D. Schmidt, A. M. Saguner
SWISS MEDICAL WEEKLY
(2022)
Correction
Cardiac & Cardiovascular Systems
Julia Cadrin-Tourigny, Laurens P. Bosman, Anna Nozza, Weijia Wang, Rafik Tadros, Aditya Bhonsale, Mimount Bourfiss, Annik Fortier, Oyvind H. Lie, Ardan M. Saguner, Anneli Svensson, Antoine Andorin, Crystal Tichnell, Brittney Murray, Katja Zeppenfeld, Maarten P. van den Berg, Folkert W. Asselbergs, Arthur A. M. Wilde, Andrew D. Krahn, Mario Talajic, Lena Rivard, Stephen Chelko, Stefan L. Zimmerman, Ihab R. Kamel, Jane E. Crosson, Daniel P. Judge, Sing-Chien Yap, Jeroen F. van der Heijden, Harikrishna Tandri, Jan D. H. Jongbloed, Marie-Claude Guertin, J. Peter van Tintelen, Pyotr G. Platonov, Firat Duru, Kristina H. Haugaa, Paul Khairy, Richard N. W. Hauer, Hugh Calkins, Anneline S. J. M. Te Riele, Cynthia A. James
EUROPEAN HEART JOURNAL
(2022)