Dual Blockade of the Renin-Angiotensin-Aldosterone System: Beyond the ACE Inhibitor and Angiotensin-II Receptor Blocker Combination

Plasma Renin Test-Guided Drug Treatment Algorithm for Correcting Patients With Treated but Uncontrolled Hypertension: A Randomized Controlled Trial

(2009) B. M. Egan et al.   AMERICAN JOURNAL OF HYPERTENSION

Effect of the Direct Renin Inhibitor Aliskiren, the Angiotensin Receptor Blocker Losartan, or Both on Left Ventricular Mass in Patients With Hypertension and Left Ventricular Hypertrophy

(2009) Scott D. Solomon et al.   CIRCULATION

Design of Combination Angiotensin Receptor Blocker and Angiotensin-Converting Enzyme Inhibitor for Treatment of Diabetic Nephropathy (VA NEPHRON-D)

(2009) L. F. Fried et al.   Clinical Journal of the American Society of Nephrology

Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial

(2009) Karl Andersen et al.   JOURNAL OF HYPERTENSION

Drug Dosing for Renoprotection: Maybe It's Time for a Drug Efficacy-Safety Score?

(2009) D. de Zeeuw et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Supramaximal Dose of Candesartan in Proteinuric Renal Disease

(2009) E. Burgess et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design

(2009) H.-H. Parving et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Renal and Retinal Effects of Enalapril and Losartan in Type 1 Diabetes

(2009) Michael Mauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aliskiren Fails to Lower Blood Pressure in Patients Who Have Either Low PRA Levels or Whose PRA Falls Insufficiently or Reactively Rises

(2008) J. E. Sealey et al.   AMERICAN JOURNAL OF HYPERTENSION

Change in Proteinuria After Adding Aldosterone Blockers to ACE Inhibitors or Angiotensin Receptor Blockers in CKD: A Systematic Review

(2008) Andrew S. Bomback et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Triple Pharmacological Blockade of the Renin-Angiotensin-Aldosterone System in Nondiabetic CKD: An Open-Label Crossover Randomized Controlled Trial

(2008) Leszek Tylicki et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Aliskiren

(2008) Morris J. Brown   CIRCULATION

Effects of the Oral Direct Renin Inhibitor Aliskiren in Patients With Symptomatic Heart Failure

(2008) John J.V. McMurray et al.   Circulation-Heart Failure

Optimal dose of lisinopril for renoprotection in type 1 diabetic patients with diabetic nephropathy: a randomised crossover trial

(2008) K. J. Schjoedt et al.   DIABETOLOGIA

Effect of Renin-Angiotensin-Aldosterone System Triple Blockade on Non-Diabetic Renal Disease: Addition of an Aldosterone Blocker, Spironolactone, to Combination Treatment with an Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker

(2008) Yoshiyuki FURUMATSU et al.   HYPERTENSION RESEARCH

Safety and Tolerability of Angiotensin-Converting Enzyme Inhibitor Versus the Combination of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker in Patients With Left Ventricular Dysfunction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2008) Rachid Lakhdar et al.   JOURNAL OF CARDIAC FAILURE

Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial

(2008) Johannes FE Mann et al.   LANCET

Aliskiren: the first renin inhibitor for clinical treatment

(2008) Chris Jensen et al.   NATURE REVIEWS DRUG DISCOVERY

Maximizing inhibition of the renin-angiotensin system with high doses of converting enzyme inhibitors or angiotensin receptor blockers

(2008) T. Berl   NEPHROLOGY DIALYSIS TRANSPLANTATION

Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy

(2008) Hans-Henrik Parving et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Renal aspirin: will all patients with chronic kidney disease one day take spironolactone?

(2008) Andrew S Bomback et al.   Nature clinical practice. Nephrology