Journal
AMERICAN JOURNAL OF HEMATOLOGY
Volume 86, Issue 12, Pages 998-1000Publisher
WILEY
DOI: 10.1002/ajh.22168
Keywords
-
Categories
Funding
- University of Iowa/Mayo Clinic Lymphoma SPORE [CA97274]
- Paul Calabresi Award for Clinical Oncology [K12 CA90628]
- Henry J. Predolin Foundation
Ask authors/readers for more resources
The serum free light chain (FLC) assay quantitates free immunoglobulin kappa and lambda light chains, which has prognostic value in plasma cell dyscrasias. However, there is limited data on serum FLC in lymphoid malignancies. We analyzed the association of pretreatment FLC with event-free survival (EFS) and overall survival (OS) in 100 patients with Hodgkin lymphoma (HL). Elevated polyclonal FLC were present in 30% of patients; these patients had an inferior EFS (HR = 4.84; 95% CI: 1.8412.7) and OS (HR = 8.87; 95% CI: 2.3533.52) compared to patients with normal FLC. Further studies of FLC in HL are warranted. Am. J. Hematol., 2011. (c) 2011 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
